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Table 3 Molecular docking of JQ1 and GSK2801 against downregulated proteins

From: Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

Protein

Glide Score

JQ1

GSK2801

PTPRC

-1.76

-2.32

MUC19

-1.04

-1.60

KCNB1

-0.95

-2.08

TAGLN

-1.60

-1.69

KISS1

-2.60

-3.01

  1. Glide docking scores of docking complexes of JQ1 and GSK2801 with downregulated proteins in TNBC. These docking scores predict the binding efficiency of drugs.