Fig. 1From: MTHFD2 is a potential oncogene for its strong association with poor prognosis and high level of immune infiltrates in urothelial carcinomas of bladderMTHFD2 expression in various cancers notably in bladder cancer (ns, p ≥ 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001). A Differential expression of MTHFD2 in various types of cancer analyzed by TIMER2.0. B The volcano plot of RNA-Seq analysis of differential expression in UCB tissues and normal bladder tissues. C Higher expression of MTHFD2 in 5637, BIU-87, EJ, T24, and TCCSUP cells than in SV-HUC-1 cells validated by western blot analysis. D Differential expression of MTHFD2 in UCB tissue samples and normal bladder tissue samples. E Differential expression of MTHFD2 in UCB tissue samples and their paired normal bladder tissue samples. F Immunohistochemistry (IHC) for the tumor and normal tissues of three BLCA patients. MTHFD2 was used for stainingBack to article page