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Table 3 Performances of SCARNA10 and AFP for the diagnosis of HCC patients

From: Serum long non-coding RNA SCARNA10 serves as a potential diagnostic biomarker for hepatocellular carcinoma

 

Sensitivity

Specificity

Cut-off

PPV

NPV

AUC

z-test

p-value

HCC vs HC

 SCARNA10

0.70

0.77

2.83 (2-△△Ct)

0.82

0.65

0.82*

5.143

< 0.01

 AFP

0.69

0.91

12.40 (ng/ml)

0.97

0.63

0.83*

3.255

< 0.01

 SCARNA10 + AFP

0.88

0.80

   

0.92

  

HCC vs BLD

 SCARNA10

0.66

0.84

1.74 (2-△△Ct)

0.82

0.63

0.80*

4.847

< 0.01

 AFP

0.67

0.89

31.20 (ng/ml)

1.00

0.45

0.82*

3.588

< 0.01

 SCARNA10 + AFP

0.89

0.82

   

0.91

  
  1. *p < 0.01 in comparison with SCARNA10 + AFP
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BMC Cancer

ISSN: 1471-2407

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