Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: Direct bone marrow injection of human bone marrow-derived stromal cells into mouse femurs results in greater prostate cancer PC-3 cell proliferation, but not specifically proliferation within the injected femurs

Fig. 1

Live animal IVIS imaging. (a) Bioluminescence signal from representative mice that received hBMSC-Luc/GFP (image time point was two weeks after transplant). (b) Graphical representation of bioluminescence hBMSC-Luc/GFP signal overtime for animals that did or did not receive PC-3-DsRed injections (8 mice with hBMSC-Luc/GFP (green), and 18 mice with hBMSC-Luc/GFP + PC-3-DsRed (red)). (c) Fluorescence signal from PC-3-DsRed, minus background fluorescence, for select mice from each group at 4 weeks (14 mice with PC-3-DsRed and 18 mice with hBMSC-Luc/GFP + PC-3-DsRed). (d) Graphical representation of PC-3-DsRed fluorescence signal from mice overtime after PC-3-DsRed injection. Pooled experiments of three biological repeats. All IVIS images are found in Supplementary Figs. 5 and 7. Statistics were not significant between curves after using linear-regression calculation and fit determined by Alkaines Information Criterion (AICc) or multiple t-tests with the Holm-Sidak method (Supplementary Fig. 6).

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us