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Correction: Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study

The Original Article was published on 08 March 2021

Correction to: BMC Cancer 21, 248 (2021)

https://doi.org/10.1186/s12885-021-07939-w

Following publication of the original article [1], an error was discovered in table 3 “Logistic regression model for use of antidepressants, sedatives and anti-epileptics, respectively, at one year following index date, for patients with LGG.” In this table, the numbers presented for anti-epileptics are equal to the numbers for the sedatives. There has been a copy error and numbers need to be adjusted. The new results do not change the conclusions. The updated table 3 is given below and the changed values are displayed in bold typeface.

Covariate Univariable Multivariable
OR (95 % CI) p-value OR (95 % CI) p-value
ANTIDEPRESSANTS
 Index year (per year) 1.22 (1.07-1.39) 0.002** 1.31 (1.11-1.55) 0.002**
 Female (vs. male) 2.99 (1.60-5.60) 0.001** 3.41 (1.71-6.80) 0.001**
 Age (per year) 1.02 (1.00-1.05) 0.027* 1.02 (1.00-1.05) 0.11
 Income (per 100.000 SEK) 0.96 (0.76-1.20) 0.69 1.07 (0.83-1.39) 0.60
 Higher education (vs. lower education) 0.94 (0.78-1.15) 0.56 0.97 (0.78-1.21) 0.78
 History of depression 7.61 (3.88-14.94) <0.001*** 6.12 (2.96-12.63) <0.001***
 Use of antidepressants preoperatively 14.15 (5.88-34.08), <0.001***   
 Elixhauser comorbidity index (0, 1, 2, >3) 1.33 (0.96-1.84) 0.09 1.09 (0.75-1.59) 0.65
 Functional level (per WHO performance status category) 0.98 (0.92-1.03) 0.38 0.96 (0.88-1.06) 0.42
 Tumour size (6) 1.08 (0.96-1-21) 0.22 0.92 (0.79-1.07) 0.30
SEDATIVES
 Index year (per year) 1.13 (0.99-1.29) 0.07 1.12 (0.97-1.30) 0.14
 Female (vs. male) 1.23 (0.66-2.30) 0.51 1.13 (0.58-2.19) 0.73
 Age (per year) 1.02 (1.00-1.04) 0.09 1.02 (0.99-1.04) 0.24
 Income (per 100.000 SEK) 0.87 (0.67-1.13) 0.30 0.90 (0.62-1.22) 0.49
 Higher education (vs. lower education) 0.81 (0.66-1.00) 0.05 0.90 (0.71-1.13) 0.35
 History of anxiety and/or sleeping difficulties 2.58 (1.36-4.90) 0.004** 2.14 (1.09-4.20) 0.027*
 use of sedatives preoperatively 3.05 (1.60-5.82), <0.001***   
 Elixhauser comorbidity index (0, 1, 2, >3) 1.37 (0.98-1.92) 0.07 1.17 (0.80-1.70) 0.41
 Functional level (per WHO performance status category) 0.97 (0.91-1.04) 0.42 0.97 (0.89-1.05) 0.43
 Tumour size (6) 1.09 (0.97-1.23) 0.17 1.00 (0.87-1.16) 0.98
ANTI-EPILEPTICS
 Index year (per year) 1.00 (0.92-1.08) 1.00 1.01 (0.92-1.12) 0.83
 Female (vs. male) 1.11 (0.75-1.64) 0.60 1.13 (0.71-1.82) 0.60
 Age (per year) 1.00 (0.98-1.01) 0.64 1.00 (0.98-1.02) 0.93
 Income (per 100.000 SEK) 1.02 (0.88-1.18) 0.79 0.94 (0.79-1.12) 0.49
 Higher education (vs. lower education) 1.04 (0.92-1.19) 0.53 1.04 (0.87-1.23) 0.69
 History of AED-use and/or seizure/epilepsy preoperatively 12.16 (7.15-20.69) <0.001*** 12.98 (7.53-22.37) <0.001***
 Elixhauser comorbidity index (0, 1, 2, >3) 0.90 (0.69-1.17) 0.42 0.93 (0.67-1.28) 0.64
 Functional level (per WHO performance status category) 1.00 (0.99-1.01) 0.85 1.00 (0.98-1.01) 0.85
 Tumour size (6) 1.03 (0.94-1.12) 0.58 1.00 (0.90-1.13) 0.94
 Biopsy vs resection 0.78 (0.49-1.25) 0.30 0.67 (0.38 –1.19) 0.17
  1. *p <0.05, **p < 0.01, ***p < 0.001

Reference

  1. Rydén I, Thurin E, Carstam L, et al. Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study. BMC Cancer. 2021;21:248. https://doi.org/10.1186/s12885-021-07939-w.

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Correspondence to Isabelle Rydén.

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Rydén, I., Thurin, E., Carstam, L. et al. Correction: Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study. BMC Cancer 22, 350 (2022). https://doi.org/10.1186/s12885-022-09400-y

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