Skip to main content

Retraction Note: Identification of novel signaling components in N,N’-Dinitrosopiperazine-mediated metastasis of nasopharyngeal Carcinoma by quantitative phosphoproteomics

The Original Article was published on 05 April 2014

Retraction Note: BMC Cancer 14, 243 (2014)

https://doi.org/10.1186/1471-2407-14-243

The Editors have retracted this Article. After publication, concerns were raised regarding the data presented in Figs. 2 and 8. Specifically:

  • Fig. 2A(c) appears highly similar to Fig. 2c in [1, retracted] and Fig. 2B(b) in [2].

  • Subpanels of Fig. 8A appear highly similar to Fig. 6d and f in [1], Fig. 4a (3rd row, 1st column) in [3], Fig. 8c in [4, retracted] and Fig. 6B(c) in [5].

The authors provided the raw data to address these concerns, but the cell images contained further overlap with the raw data submitted for another paper under investigation. The Editors therefore no longer have confidence in the presented data.

Author Faqing Tang has not specifically stated whether they agree with the retraction. Authors Yuejin Li, Na Liu, Zhenlin Zhang, Zhengke Peng, Chaojun Duan and Gongjun Tan have not responded to any correspondence from the Editor or Publisher about this retraction. The Publisher has not been able to obtain current email addresses for authors Guangrong Yan, Damao Huang and Xiaowei Tang.

References

  1. Tan G, Tang X, et al. Dinitrosopiperazine-mediated phosphorylated-proteins are involved in nasopharyngeal carcinoma metastasis. Int J Mol Sci. 2014;15(11):20054–71. https://doi.org/10.3390/ijms151120054.

  2. Lu J, Zhang ZL, et al. Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis. Oncotarget. 2016;7(6):7012. https://doi.org/10.18632/oncotarget.6875.

  3. Tang F, Wang D, et al. Berberine inhibits metastasis of nasopharyngeal carcinoma 5–8F cells by targeting Rho kinasemediated Ezrin phosphorylation at threonine 567. J Biol Chem. 2009;284(40):27456–66. https://doi.org/10.1074/jbc.M109.033795.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Zhou S, Lu J, Li Y, et al. RETRACTED ARTICLE: MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance. J Exp Clin Cancer Res. 2018;37:284. https://doi.org/10.1186/s13046-018-0956-3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Peng Z, Liu N, et al. N, N'-dinitrosopiperazine–mediated heat-shock protein 70-2 expression is involved in metastasis of nasopharyngeal carcinoma. PLoS one. 2013;8(5):e62908. https://doi.org/10.1371/journal.pone.0062908.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Faqing Tang.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

About this article

Verify currency and authenticity via CrossMark

Cite this article

Huang, D., Li, Y., Liu, N. et al. Retraction Note: Identification of novel signaling components in N,N’-Dinitrosopiperazine-mediated metastasis of nasopharyngeal Carcinoma by quantitative phosphoproteomics. BMC Cancer 22, 324 (2022). https://doi.org/10.1186/s12885-022-09365-y

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s12885-022-09365-y