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Table 1 Clinicopathological features of 378 patients who were treated with preoperative chemotherapy

From: Clinical verification of body mass index and tumor immune response in patients with breast cancer receiving preoperative chemotherapy

Parameters (n = 378)

Number of patients (%)

Age (years old)

56 (24–78)

Tumor size (mm)

28.7 (9.2–119.8)

Skin infiltration Negative / Positive

318 (84.1%) / 60 (15.9%)

Lymph node metastasis N0 / N1 / N2 / N3

132 (34.9%) / 140 (37.0%) / 71 (18.8%) / 35 (9.3%)

Estrogen receptor Negative / Positive

223 (59.0%) / 155 (41.0%)

Progesterone receptor Negative / Positive

301 (79.6%) / 77 (20.4%)

HER2 Negative / Positive

238 (63.0%) / 140 (37.0%)

Ki67 ≤ 14% / > 14%

121 (32.0%) / 257 (68.0%)

Intrinsic subtype HRBC / HER2BC / TNBC

159 (42.1%) / 93 (24.6%) / 126 (33.3%)

Objective response rate Non-Responders / Responders

41 (10.8%) / 337 (89.2%)

Pathological response Non-pCR / pCR

250 (66.1%) / 128 (33.9%)

TILs Low / High

209 (55.3%) / 169 (44.7%)

Body mass index (kg/m2)

21.9 (14.3–38.5)

Body mass index categorized Underweight / Normal / Overweight / Obese

49 (13.0%) / 244 (64.5%) / 66 (17.5%) / 19 (5.0%)

  1. HER: human epidermal growth factor receptor. HRBC: hormone receptor-positive breast cancer (ER+ and/or PgR+). HER2BC: human epidermal growth factor receptor 2-enriched breast cancer (ER-, PgR-, and HER2+). TNBC: triple negative breast cancer (ER-, PgR-, and HER2-). pCR: pathological complete response. TILs: tumor-infiltrating lymphocytes