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Table 4 The association of HBV infection with the risk of CRC (exclude participants who occurred HCC within 1 year)

From: Associations between hepatitis B virus infection and risk of colorectal Cancer: a population-based prospective study

 

HBsAg Seronegative

HBsAg Seropositive

Adjusted Hazard Ratios

(95% CI)

Cases

Person-years

Cases

Person-years

Model 1

391

1,042,341

18

28,600

1.68(1.05 ~ 2.69)

Model 2

391

1,042,341

18

28,600

1.98(1.23 ~ 3.17)

Model 3

391

1,042,341

18

28,600

2.05(1.28 ~ 3.30)

  1. Note:
  2. Model 1: Univariate analysis
  3. Model 2: Adjusted for age (every 10 years), sex based on model 1
  4. Model 3: Further adjusted for BMI (normal, overweight, obesity), hypercholesterolemia, hypertriglyceridemia, hs-CRP (< 1 mg/L, 1–3 mg/L, > 3 mg/L), hyperbilirubinemia, elevated alanine aminotransferase, diabetes, family income, educational background, marital status, salt consumption, current smoker, drinking status, physical activity and family history of cancer based on model 2