Table 1 Correlations between the expression of STX4 and clinicopathologic characteristics in KIRC
Characteristic | n (%) | Expression of STX4 (%) | P-value | |
|---|---|---|---|---|
High | Low | |||
Total | 535 (100) | 267 (49.91) | 268 (50.09) | |
Age | 0.437 | |||
ZA ≤ 60 years | 267 (49.91) | 138 (51.7) | 129 (48.1) | |
> 60 years | 268 (50.09) | 129 (48.3) | 139 (51.9) | |
Gender | 0.277 | |||
Female | 186 (34.77) | 99 (37.1) | 87 (32.5) | |
Male | 349 (65.23) | 168 (62.9) | 181 (67.5) | |
Cancer status | 0.003 | |||
Tumor free | 336 (62.8) | 155 (58.1) | 181 (67.5) | |
With tumor | 148 (27.66) | 90 (33.7) | 58 (21.6) | |
Unknow | 51 (9.53) | 22 (8.2) | 29 (10.8) | |
Race | 0.191 | |||
White | 463 (86.54) | 226 (84.6) | 237 (88.4) | |
Asian | 8 (1.5) | 4 (1.5) | 4 (1.5) | |
Black | 57 (10.65) | 35 (13.1) | 22 (8.2) | |
Unknow | 7 (1.31) | 2 (0.7) | 5 (1.9) | |
Grade | < 0.001 | |||
G1 | 14 (2.62) | 8 (3.0) | 6 (2.2) | |
G2 | 231 (43.18) | 91 (34.1) | 140 (52.2) | |
G3 | 207 (38.69) | 119 (44.6) | 88 (32.8) | |
G4 | 75 (14.02) | 48 (18.0) | 27 (10.1) | |
Unknow | 8 (1.5) | 1 (0.4) | 7 (2.6) | |
T stage | < 0.001 | |||
T1 | 275 (51.4) | 164 (61.4) | 111 (41.4) | |
T2 | 70 (13.08) | 32 (12.0) | 38 (14.2) | |
T3 | 179 (33.46) | 70 (26.2) | 109 (40.7) | |
T4 | 11 (2.06) | 1 (0.4) | 10 (3.7) | |
N stage | 0.616 | |||
N0 | 240 (44.86) | 118 (44.2) | 122 (45.5) | |
N1 | 16 (2.99) | 9 (3.4) | 7 (2.6) | |
Unknow | 279 (52.15) | 140 (52.4) | 139 (51.9) | |
M stage | < 0.001 | |||
M0 | 424 (79.25) | 188 (70.4) | 236 (88.1) | |
M1 | 78 (14.58) | 52 (19.5) | 26 (9.7) | |
Unknow | 33 (6.17) | 27 (10.1) | 6 (2.2) | |
AJCC stage | < 0.001 | |||
Stage I | 269 (50.28) | 110 (41.2) | 159 (59.3) | |
Stage II | 58 (10.84) | 29 (10.9) | 29 (10.8) | |
Stage III | 123 (22.99) | 72 (27.0) | 51 (19.0) | |
Stage IV | 82 (15.33) | 54 (20.2) | 28 (10.4) | |
Unknow | 3 (0.56) | 2 (0.7) | 1 (0.4) | |