Fig. 4

Inhibition of melanoma cells after treatment with compound 9. A Representative experiment of the Wound Healing test at 0, 24 and 48 h of treatment with compound 9 (2.6, 5.3 and 10.3 μM). 40x magnification. 100 μm scale bar. B Percentage wound closure. Data represent mean ± SD of three independent experiments. Doxorubicin (10 μM) was used as positive control. Analysis between groups was performed with Anova Two-Way, followed by a Dunnett post-test. Comparisons were made between treatments and control of different times (*) p < 0.05, (**) p < 0.01