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Table 4 List of other adverse events

From: Distribution of chimeric antigen receptor-modified T cells against CD19 in B-cell malignancies

Adverse events

Grade

I

II

III

IV

Blood

 Decrease of leukocyte count

 

3

5

3

 Decrease of lymphocyte count

 

3

 

4

 Decrease of neutrophil count

 

3

1

7

 Decrease of platelet count

1

3

1

 

 Increase of C-reactive protein

2

   

 Degree III leukocyte bone marrow suppression

  

1

 

 Anemia

2

3

2

 

 Increase of serum ferritin

1

   

Liver

 Elevated Alanine aminotransferase

1

   

 Elevated Aspartate aminotransferase

1

   

Pain

 Pain in the jaws

   

1

 Muscular soreness

1

   

 Pain in the left ilium

 

1

  

Immune globulin

 Decrease of immunoglobulin A

3

   

 Decrease of immunoglobulin G

3

   

 Decrease of immunoglobulin M

3

   

Digestive tract

 Diarrhea

 

2

  

 Gastrointestinal reaction

1

   

 Sick

  

1

 

 Vomit

  

1

 

 Dental ulcer

1

   

Respiratory tract

 Cough

1

   

 Upper respiratory infection

1

1

  

 Pneumonia

  

3

 

Cardiovascular

 Nodal tachycardia

2

   

Others

 Insomnia

 

1

  

 Elevated urinary white blood cells

 

1

  

 Feeble

1

   

 Headache

1

   

 Elevated thyroid stimulating hormone

1

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