Table 2 Results of 67 genes that showed significant relationship between methylation in the non-promoter region and gene expression
Gene | Mean of Δβ values of probes in the non-promoter region averaged over all patients | log2 fold-change of gene-expression values averaged over all patients |
|---|---|---|
ABCA3 | −0.242 | −2.740 |
ADAMTS17 | −0.235 | −1.418 |
ADCY2 | − 0.282 | −4.311 |
ADCYAP1R1 | −0.231 | −3.227 |
AFAP1L2 | 0.278 | 1.749 |
AGRN | 0.299 | 1.830 |
ANGPT1 | −0.255 | −1.084 |
ANK2 | −0.292 | −3.425 |
ARNT2 | −0.257 | −1.056 |
ATP8A1 | −0.263 | −1.419 |
BCL11B | 0.344 | 1.154 |
BMPER | −0.226 | −2.030 |
BNC2 | −0.284 | − 2.276 |
CACNA1D | −0.261 | −2.461 |
CACNA2D1 | −0.256 | −2.616 |
CADM1 | −0.256 | −1.519 |
CDCA7 | 0.235 | 1.265 |
CIT | 0.274 | 1.201 |
CLIC5 | −0.264 | −3.547 |
COBL | −0.283 | −3.073 |
COL27A1 | 0.323 | 1.918 |
DNAH17 | 0.228 | 3.230 |
EEPD1 | −0.245 | −1.291 |
EGFR | 0.240 | 1.147 |
EPHB2 | 0.285 | 2.239 |
EPSTI1 | 0.269 | 2.851 |
EXT1 | 0.272 | 1.068 |
FAM13C | −0.340 | −1.862 |
FAM171A1 | −0.232 | −1.712 |
FGD5 | −0.266 | −1.149 |
FHIT | −0.289 | −2.022 |
GFI1 | 0.318 | 1.787 |
ICAM5 | 0.301 | 1.476 |
IGDCC4 | −0.296 | −2.178 |
KCNAB1 | −0.279 | −1.560 |
LAMB4 | −0.206 | − 1.731 |
LDB2 | −0.268 | −1.250 |
LRP8 | 0.227 | 1.393 |
MCF2L | −0.242 | −2.238 |
MEGF11 | −0.257 | −1.094 |
NCS1 | 0.290 | 1.266 |
NDRG1 | 0.208 | 1.343 |
NKAIN1 | −0.241 | −1.384 |
NTRK3 | −0.298 | −3.202 |
PALM | −0.274 | −2.500 |
PAPPA | 0.258 | 1.324 |
PARK2 | −0.278 | −2.854 |
PDZRN3 | −0.250 | −1.409 |
PLCL1 | −0.243 | −1.626 |
PML | 0.220 | 1.562 |
PPM1L | −0.303 | −2.386 |
PRKD1 | −0.276 | −1.051 |
RGS20 | 0.221 | 2.582 |
RTKN | 0.235 | 1.183 |
SCIN | −0.278 | −3.784 |
SDK2 | 0.247 | 2.410 |
SLC6A17 | −0.240 | −1.586 |
SLC7A5 | 0.241 | 1.367 |
SOBP | −0.286 | −2.687 |
SPRED3 | 0.280 | 1.989 |
SUSD4 | −0.319 | −1.780 |
TECTA | −0.286 | −1.007 |
TENM2 | 0.275 | 2.951 |
TMEM232 | −0.213 | −1.995 |
TRAM2 | 0.264 | 1.327 |
WNK2 | −0.217 | −3.895 |
ZNF423 | −0.254 | −1.799 |