Yoon JY, Lee JD, Joo SW, et al. Indoor radon exposure and lung cancer: a review of ecological studies. Ann Occup Environ Med. 2016;28:15.
Darby S, Hill D, Auvinen A, et al. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ. 2005;330:223.
Kendall GM, Smith TJ. Doses to organs and tissues from radon and its decay products. J Radiol Prot. 2002;22:389–406.
Robertson A, Allen J, Laney R, et al. The cellular and molecular carcinogenic effects of radon exposure: a review. Int J Mol Sci. 2013;14:14024–63.
Jostes RF. Genetic, cytogenetic, and carcinogenic effects of radon: a review. Mutat Res. 1996;340:125–39.
Evans HH, Mencl J, Hui TE, et al. Cytotoxic and mutagenic effects of radon and radon daughters on murine L5178Y lines differing in DNA repair. Radiat Res. 1993;136:57–64.
Lindholm C, Makelainen I, Paile W, et al. Domestic radon exposure and the frequency of stable or unstable chromosomal aberrations in lymphocytes. Int J Radiat Biol. 1999;75:921–8.
Meenakshi C, Mohankumar MN. Relative biological effectiveness of radon: an in vitro study using chromosome aberrations as a biomarker. Int J Radiat Biol. 2015;91:681–5.
Lehnert BE, Goodwin EH, Deshpande A. Extracellular factor(s) following exposure to alpha particles can cause sister chromatid exchanges in normal human cells. Cancer Res. 1997;57:2164–71.
Lehnert BE, Goodwin EH. A new mechanism for DNA alterations induced by alpha particles such as those emitted by radon and radon progeny. Environ Health Perspect. 1997;105(Suppl 5):1095–101.
Brooks AL, Khan MA, Duncan A, et al. Effectiveness of radon relative to acute 60Co gamma-rays for induction of micronuclei in vitro and in vivo. Int J Radiat Biol. 1994;66:801–8.
Lorenzo-Gonzalez M, Ruano-Ravina A, Torres-Duran M, et al. Residential radon, genetic polymorphisms in DNA damage and repair-related. Lung Cancer. 2019;135:10–5.
Minina VI, Sinitsky MY, Druzhinin VG, et al. Chromosome aberrations in peripheral blood lymphocytes of lung cancer patients exposed to radon and air pollution. Eur J Cancer Prev. 2018;27:6–12.
Druzhinin VG, Sinitsky MY, Larionov AV, et al. Assessing the level of chromosome aberrations in peripheral blood lymphocytes in long-term resident children under conditions of high exposure to radon and its decay products. Mutagenesis. 2015;30:677–83.
Oestreicher U, Braselmann H, Stephan G. Cytogenetic analyses in peripheral lymphocytes of persons living in houses with increased levels of indoor radon concentrations. Cytogenet Genome Res. 2004;104:232–6.
Barbosa-Lorenzo R, Barros-Dios JM, Raices Aldrey M, et al. Residential radon and cancers other than lung cancer: a cohort study in Galicia, a Spanish radon-prone area. Eur J Epidemiol. 2016;31:437–41.
VoPham T, DuPre N, Tamimi RM, et al. Environmental radon exposure and breast cancer risk in the Nurses' health study II. Environ Health. 2017;16:97.
De Bacco F, Luraghi P, Medico E, et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. J Natl Cancer Inst. 2011;103:645–61.
Bravata V, Minafra L, Russo G, et al. High-dose ionizing radiation regulates gene expression changes in the MCF7 breast Cancer cell line. Anticancer Res. 2015;35:2577–91.
Pucci M, Bravata V, Forte GI, et al. Caveolin-1, breast cancer and ionizing radiation. Cancer Genomics Proteomics. 2015;12:143–52.
Eliassen AH, Colditz GA, Rosner B, et al. Adult weight change and risk of postmenopausal breast cancer. JAMA. 2006;296:193–201.
Poole EM, Tworoger SS, Hankinson SE, et al. Body size in early life and adult levels of insulin-like growth factor 1 and insulin-like growth factor binding protein 3. Am J Epidemiol. 2011;174:642–51.
Price PN. Predictions and maps of county mean indoor radon concentrations in the mid-Atlantic states. Health Phys. 1997;72:893–906.
Price PNA. Joint analysis of long- and short-term radon monitoring data from the northern U.S. Environ Int. 1996:699–714.
Tamimi RM, Baer HJ, Marotti J, et al. Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer. Breast Cancer Res. 2008;10:R67.
Sisti JS, Collins LC, Beck AH, et al. Reproductive risk factors in relation to molecular subtypes of breast cancer: results from the nurses' health studies. Int J Cancer. 2016;138:2346–56.
Kensler KH, Sankar VN, Wang J, et al. PAM50 molecular intrinsic subtypes in the Nurses' health study cohorts. Cancer Epidemiol Biomark Prev. 2019;28:798–806.
Wang J, Heng YJ, Eliassen AH, et al. Alcohol consumption and breast tumor gene expression. Breast Cancer Res. 2017;19:108.
Heng YJ, Wang J, Ahearn TU, et al. Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues. Breast Cancer Res Treat. 2018.
Kensler KH, Sankar VN, Wang J, et al. PAM50 molecular intrinsic subtypes in the Nurses' health study cohorts. Cancer Epidemiol Biomark Prev. 2018;28:798.
Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007;8:118–27.
Viswanathan AN, Feskanich D, De Vivo I, et al. Smoking and the risk of endometrial cancer: results from the Nurses' health study. Int J Cancer. 2005;114:996–1001.
Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3.
EPA. A Citizen's Guide to Radon: The Guide to Protecting Yourself and Your Family from Radon. EPA402/K-12/002|2016| www.epa.gov/radon. https://www.epa.gov/sites/production/files/2016-12/documents/2016_a_citizens_guide_to_radon.pdf.
EPA Assessment of Risks fromRadon in Homes in Agency USEP (ed). Office of Radiation and Indoor Air United States Environmental Protection Agency Washington, DC 20460, 2003.
Leek JT, Storey JD. Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet. 2007;3:1724–35.
YH YB. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Series B. 1995;57:289–300.
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102:15545–50.
Luch A. Nature and nurture - lessons from chemical carcinogenesis. Nat Rev Cancer. 2005;5:113–25.
Harley NH, Harley JH. Potential lung cancer risk from indoor radon exposure. CA Cancer J Clin. 1990;40:265–75.
Lubin JH, Boice JD Jr, Edling C, et al. Lung cancer in radon-exposed miners and estimation of risk from indoor exposure. J Natl Cancer Inst. 1995;87:817–27.
Schoenberg J. KJ: a case-control study of radon and lung cancer among New Jersey women, Phase I: New Jersey State Department of Health; 1989.
Auvinen A, Makelainen I, Hakama M, et al. Indoor radon exposure and risk of lung cancer: a nested case-control study in Finland. J Natl Cancer Inst. 1996;88:966–72.
Schoenberg JB, Klotz JB, Wilcox HB, et al. Case-control study of residential radon and lung cancer among New Jersey women. Cancer Res. 1990;50:6520–4.
Barros-Dios JM, Barreiro MA, Ruano-Ravina A, et al. Exposure to residential radon and lung cancer in Spain: a population-based case-control study. Am J Epidemiol. 2002;156:548–55.
Lorenzo-Gonzalez M, Ruano-Ravina A, Torres-Duran M, et al. Lung cancer and residential radon in never-smokers: a pooling study in the northwest of Spain. Environ Res. 2019;172:713–8.
National Research Council, Evaluation of Guidelines for Exposures to Technologically Enhanced Naturally Occurring Radioactive Materials. Washington (DC), 1999.
Suzuki K, Kodama S, Watanabe M. Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells. Cancer Res. 2001;61:5396–401.
Kutanzi K, Kovalchuk O. Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats. Cancer Biol Ther. 2013;14:564–73.
Wang X, McGowan CH, Zhao M, et al. Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest. Mol Cell Biol. 2000;20:4543–52.
Haimovitz-Friedman A, Kan CC, Ehleiter D, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med. 1994;180:525–35.
Katz-Brull R, Seger D, Rivenson-Segal D, et al. Metabolic markers of breast cancer: enhanced choline metabolism and reduced choline-ether-phospholipid synthesis. Cancer Res. 2002;62:1966–70.
Xu X, Gammon MD, Zeisel SH, et al. High intakes of choline and betaine reduce breast cancer mortality in a population-based study. FASEB J. 2009;23:4022–8.
Cho E, Holmes MD, Hankinson SE, et al. Choline and betaine intake and risk of breast cancer among post-menopausal women. Br J Cancer. 2010;102:489–94.
Dusaban SS, Purcell NH, Rockenstein E, et al. Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proc Natl Acad Sci U S A. 2013;110:3609–14.
Citro S, Malik S, Oestreich EA, et al. Phospholipase Cepsilon is a nexus for rho and rap-mediated G protein-coupled receptor-induced astrocyte proliferation. Proc Natl Acad Sci U S A. 2007;104:15543–8.
Aran D, Camarda R, Odegaard J, et al. Comprehensive analysis of normal adjacent to tumor transcriptomes. Nat Commun. 2017;8:1077.
Cook NR, Rosner BA, Hankinson SE, et al. Mammographic screening and risk factors for breast cancer. Am J Epidemiol. 2009;170:1422–32.
Turner MC, Krewski D, Chen Y, et al. Radon and lung cancer in the American Cancer Society cohort. Cancer Epidemiol Biomark Prev. 2011;20:438–48.