Skip to main content

Table 3 Summary of compound cytotoxicity in HeLa cells

From: The interactions of novel mononuclear platinum-based complexes with DNA

Compound IC50 (μM)α Drug concentration at which complete cell death was obtained (μM)
Cisplatin 9.3 ± 0.2 30
[Pt(RR-DACH)Cl2] 12.3 ± 4.0 100
[Pt(RR-DACP)Cl2] 6.9 ± 1.0 50
[Pt(SS-DACP)Cl2] 13.7 ± 2.0 50
[Pt(4FH)Cl2] 28.8 ± 1.6 >  200
  1. αThese IC50 values represent the drug concentration at which a cell viability of 50% was obtained and were determined by non-linear regression. Each IC50 value was determined from the average of three separate experimental values and is reported along with its corresponding SEM value
\