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  • Correction
  • Open Access

Correction to: Epigenetic regulation of L1CAM in endometrial carcinoma: comparison to cancer–testis (CT-X) antigens

  • 1,
  • 2,
  • 1,
  • 2,
  • 2,
  • 3,
  • 3 and
  • 1Email author
BMC Cancer201818:1047

https://doi.org/10.1186/s12885-018-4928-y

  • Received: 10 October 2018
  • Accepted: 10 October 2018
  • Published:

The original article was published in BMC Cancer 2013 13:156

Correction

Following publication of the original article [1], we have been alerted to errors in Figs. 2 and 8. In Fig. 2b, the GAPDH loading control for Hec1A cells is shown twice in error (in Fig. 2b and Fig. 2c). In Fig. 8, in testis case 1 (first column) the MAGE-A4 staining panel was repeated and also appears as the NY-ESO-1 staining panel in error. The corrected versions of Fig. 2 and Fig. 8 are shown below. We apologize for this inconvenience.
Fig. 2
Fig. 2

Regulation of L1CAM expression by epigenetic mechanisms. (a) RT-PCR analysis of cells treated for 5 days with the indicated concentration of 5-AzaC, TSA or both compounds. DMSO was used as a mock control. Cells were lysed and mRNA was isolated and transcribed into cDNA. β-actin served as internal standard. (b) Cells were treated as described above and cell lysates were prepared for Western blot analysis. MAb L1-11A was used as a primary antibody followed by peroxidase conjugated Goat anti mouse IgG and ECL detection. (c) TSA and VA up-regulate L1CAM expression. Cells were treated and analyzed as described in (b)

Fig. 8
Fig. 8

IHC analysis of testis and EC tissues. Expression of NY-ESO-1 and MAGE-A4 but absence of L1CAM in normal human testis tissue. Conversely, L1CAM is expressed in type II EC but NY-ESO-1 and MAGE-A4 are undetectable. Note that a representative case of n = 5 is shown. Sequential tissue sections were analysed by IHC

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of Translational Immunology, German Cancer Research Center, D015, D 69120 Heidelberg, Germany
(2)
Department of Gynecology and Obstetrics, Medical University of Innsbruck, A 6020 Innsbruck, Austria
(3)
Institute of Surgical Pathology, University Hospital Zürich, Zürich, Switzerland

Reference

  1. Schirmer U, et al. Epigenetic regulation of L1CAM in endometrial carcinoma: comparison to cancer–testis (CT-X) antigens. BMC Cancer. 2013;13:156. https://doi.org/10.1186/1471-2407-13-156.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s). 2018

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