Table 1 A selected list of genes associated with replication and DNA Repair

ATR

ATR Serine/Threonine Kinase

3q23

ATRIP

ATR Interacting Protein

3p21.31

BAP1

BRCA1 Associated Protein 1

3p21.1

CDC45

Cell Division Cycle 45

22q11.21

CHEK1

Checkpoint Kinase 1

11q24.2

CIZ1

CDKN1A Interacting Zinc Finger Protein 1

9q34.11

EXO1

Exonuclease 1

1q43

FEN1

Flap Structure-Specific Endonuclease 1

11q12.2

GINS1

GINS Complex Subunit 1

20p11.21

GINS2

GINS Complex Subunit 2

16q24.1

GINS3

GINS Complex Subunit 3

16q21

GINS4

GINS Complex Subunit 4

8p11.21

HUS1

HUS1 Checkpoint Clamp Component

7p12.3

LIG1

DNA Ligase 1

19q13.33

MCM2

Minichromosome Maintenance Complex Component 2

3q21.3

MCM3

Minichromosome Maintenance Complex Component 3

6p12.2

MCM4

Minichromosome Maintenance Complex Component 4

8q11.21

MCM5

Minichromosome Maintenance Complex Component 5

22q12.3

MCM6

Minichromosome Maintenance Complex Component 6

2q21.3

MCM7

Minichromosome Maintenance Complex Component 7

7q22.1

MCM10

Replication Initiation Factor

10p13

MLH1

MutL Homolog 1

3p22.2

MLH3

MutL Homolog 3

14q24.3

MSH2

MutS Homolog 2

2p21 -p16.3

MSH3

MutS Homolog 3

5q14.1

MSH6

MutS Homolog 6

2p16.3

PCNA

Proliferating Cell Nuclear Antigen

20p12.3

PMS1

PMS1 Homolog 1, Mismatch Repair System Component

2q32.2

PMS2

PMS1 Homolog 2, Mismatch Repair System Component

7p22.1

POLD1

DNA Polymerase Delta 1, Catalytic Subunit

19q13.33

POLE

DNA Polymerase Epsilon, Catalytic Subunit

12q24.33

RAD1

RAD1 Checkpoint DNA Exonuclease

5p13.2

RAD17

RAD17 Checkpoint Clamp Loader Component

5q13.2

RAD9A

RAD9 Checkpoint Clamp Component A

11q13.2

RFC4

Replication Factor C Subunit 4

3q27.3

RPA1

Replication Protein A1

17p13.3

RPS19

Ribosomal Protein S19

19q13.2