Risk factors for esophageal fistula in thoracic esophageal squamous cell carcinoma invading adjacent organs treated with definitive chemoradiotherapy: a monocentric case-control study

Table 3 Multivariate analysis for the incidence of esophageal fistula

Characteristics	EF+ (N = 28)	EF− (N = 88)	OR	95% CI	P-value
Total circumferential lesion	20	40	3.09	1.14–8.39	0.027
Aorta invasion	16	38	2.56	0.97–6.75	0.058
CRP ≥ 1.00 mg/dL^a	19	29	5.19	1.93–13.9	0.001

Abbreviations: EF esophageal fistula, OR odds ratio, CI confidence interval, CRP C reactive protein
^aData missing for two patients

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