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Table 1 Characteristics of control and lung cancer cases and association between cigarette smoking and risk of lung cancer

From: Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population

 

Control n = 150

Lung cancer n = 150

P value

Age(years) Mean + SD

43.3 ± 11.1

56.7 ± 9.79

<  0.001

Sex n(%)

 Male

73 (48.7%)

114 (76%)

< 0.0001

 Female

77 (51.3%)

36 (24%)

 

Histological Types n (%)

 SCLC

20 (13.3%)

 NSCLC

130 (87.7%)

  Adenocarcinoma

73 (56.2%)

  Squamous cell carcinoma

18 (13.8%)

  Othersa

39 (30%)

 

Control n (%)

Lung cancer n (%)

OR (95% C.I.)

P value

Smoking Status

 Smoker n (%)

30(20%)

93(62%)

2.78 (2.0–3.86)

0.0001

 Non-smoker n (%)

120(80%)

57(38%)

  

Pack-year

  < 20 n (%)

16(53.3%)

37(39.8%)

0.58 (0.25–1.32)

NS

  > 20 n (%)

14(46.7%)

56(60.2%)

  
  1. SCLC small cell lung cancer, NSCLC non- small cell lung cancer
  2. aLarge cell carcinoma, undifferentiated, spindle, mucinous, Broncho alveolar carcinoma, carcinoid, sarcomatoid carcinoma, anaplastic