Fig. 9From: 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cellsThe possibility of development of a new alternative strategy that can utilize COX-2 or 5-LO activity itself in cancer cells. Considering our observation that DHEA and NALA produced more ROS through the 5-LO pathway than AA, we suggest the possibility of development of a new alternative strategy that can utilize COX-2 or 5-LO activity itself in cancer cells but is different from direct inhibition of COX-2 or 5-LOBack to article page