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Fig. 9 | BMC Cancer

Fig. 9

From: 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells

Fig. 9

The possibility of development of a new alternative strategy that can utilize COX-2 or 5-LO activity itself in cancer cells. Considering our observation that DHEA and NALA produced more ROS through the 5-LO pathway than AA, we suggest the possibility of development of a new alternative strategy that can utilize COX-2 or 5-LO activity itself in cancer cells but is different from direct inhibition of COX-2 or 5-LO

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