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Table 3 Risk allele load and risk for cervical cancer

From: Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study

SNP’s −590 (IL-4)/-573 (IL-6)/-592 (IL-10)/-819 (IL-10)/-509 (TGFB1)
Number of alleles associated with CC n ORa CI 95 % P value
  Total CC Controls    
0 312 119 193 1 -  
1 116 60 56 1.4 0.832–2.386 0.2
2 133 69 64 1.75 1.072–2.881 0.02
3 137 85 52 2.54 1.563–4.159 0.0001
≥4 99 66 33 2.86 1.608–5.098 0.0001
P trend 0.0001
  1. n = Number of alleles
  2. aOdds Ratio adjusted by age, CC history and smoking history
  3. Bold text denotes significant p values (p < 0.05)
  4. Trend p value adjusted by age, CC history and smoking history