Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study

Table 3 Risk allele load and risk for cervical cancer

SNP’s −590 (IL-4)/-573 (IL-6)/-592 (IL-10)/-819 (IL-10)/-509 (TGFB1)
Number of alleles associated with CC	n			OR^a	CI 95 %	P value
	Total	CC	Controls
0	312	119	193	1	-
1	116	60	56	1.4	0.832–2.386	0.2
2	133	69	64	1.75	1.072–2.881	0.02
3	137	85	52	2.54	1.563–4.159	0.0001
≥4	99	66	33	2.86	1.608–5.098	0.0001
P trend						0.0001

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