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Fig. 2 | BMC Cancer

Fig. 2

From: Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling

Fig. 2

Autophagy regulation by Obatoclax in 3D long term cell culture. a HT29 cells were seeded on glass slides, grown for 7 days and treated with 0.25 μM obatoclax. Immunhistochemical staining was done for p62 and LC3b. b HT29 cells in scaffolds after 7 days treatment with obatoclax. Immunhistochemical staining for p62 and LC3b. Representative pictures for at least 3 experiments are shown. Scale bar indicates 200 μm for longitudinal sections and 50 μM for corresponding insets. DMSO served as vehicle

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BMC Cancer

ISSN: 1471-2407

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