Table 2 Odds ratios (OR), population attributable risks (PAR) and confidence intervals (95 % CI) for oral cavity cancer associated with body mass index, family history of head and neck cancer, history of oral candidiasis, and tea consumption, overall and by subsite, gender and age. ICARE study

 Oral cavity overall

408/253

1405/1944

2.4 (1.8–3.0)

35.3 % (25.7–43.6)

 By subsite

Base of tongue

67/56

1405/1944

2.9 (1.8–5.0)

42.4 % (20.5–58.2)

Mobile tongue

91/64

1405/1944

1.9 (1.2–2.9)

25.8 % (5.1–42.1)

Gums

23/13

1405/1944

4.2 (1.5–12.2)

55.1 % (4.7–78.9)

Floor of mouth

110/71

1405/1944

2.4 (1.6–3.6)

35.3 % (17.9–49.1)

Soft palate

49/22

1405/1944

2.6 (1.4–4.8)

37.6 % (9.6–56.9)

Other parts of the mouth

56/22

1405/1944

2.7 (1.4–5.1)

39.1 % (10.1–58.8)

 By gender

Male

332/203

1022/1600

2.8 (2.1–3.6)

39.9 % (30.0–48.3)

Female

76/50

383/344

1.1 (0.6–2.0)

4.2 % (−38.4–33.7)

 By age

<45

33/12

222/177

3.1 (1.0–9.1)

47.3 % (2.1–72.8)

45–60

272/144

601/797

2.6 (1.8–3.6)

40.4 % (27.3–51.2)

>60

103/97

582/970

2.1 (1.4–3.1)

26.7 % (11.3–39.5)

 Oral cavity overall

68/462

157/2784

1.9 (1.3–2.8)

5.8 % (0.6–10.8)

 By subsite

Base of tongue

17/73

157/2784

2.6 (1.3–5.3)

11.2 % (−0.9–21.9)

Mobile tongue

17/106

157/2784

2.5 (1.3–4.8)

8.6 % (−0.9–17.3)

Gums

1/24

157/2784

0.9 (0.1–7.5)

- **

Floor of mouth

13/138

157/2784

1.6 (0.8–3.3)

3.4 % (−5.0–11.1)

Soft palate

9/50

157/2784

2.4 (0.9–6.1)

7.0 % (−6.1–18.6)

Other parts of the mouth

5/58

157/2784

1.1 (0.3–3.3)

0.6 % (−12.5–12.2)

 By gender

Male

54/375

120/2184

2.1 (1.4–3.3)

6.8 % (1.0–12.2)

Female

10/87

37/600

1.3 (0.4–3.9)

2.1 % (−12.9–15.1)

 By age

<45

3/35

16/353

4.9 (0.9–27.2)

8.5 % (−14.1–26.7)

45–60

41/293

67/1189

2.0 (1.1–3.6)

6.7 % (−0.4–13.3)

>60

20/134

74/1242

1.6 (0.8–3.0)

4.0 % (−4.1–11.5)

 Oral cavity overall

14/645

80/3224

4.2 (1.7–10.5)

1.9 % (−2.1–5.7)

 By subsite

Base of tongue

3/120

80/3224

1.7 (0.2–17.3)

0.6 % (−7.1–7.7)

Mobile tongue

5/145

80/3224

9.2 (2.9–29.1)

4.9 % (−1.8–11.3)

Gums

0/36

80/3224

not estimated

Floor of mouth

3/180

80/3224

3.9 (0.8–20.2)

1.2 % (−5.2–7.3)

Soft palate

1/71

80/3224

3.3 (0.3–35.9)

1.4 % (−7.8–9.9)

Other parts of the mouth

1/77

80/3224

3.6 (0.4–32.9)

1.6 % (−7.3–9.7)

 By gender

Male

10/526

41/2548

2.9 (0.8–10.1)

1.2 % (−3.2–5.3)

Female

4/119

39/676

5.2 (1.1–24.8)

4.6 % (−6.9–14.8)

 By age

<45

0/41

21/389

not estimated

45–60

10/403

27/1341

9.8 (2.7–35.9)

2.9 % (−2.2–7.8)

>60

4/201

32/1494

1.6 (0.3–8.6)

0.6 % (−5.1–5.9)

 Oral cavity overall

443/150

2025/1334

1.7 (1.3–2.2)

30.3 % (14.4–43.3)

 By subsite

Base of tongue

80/37

2025/1334

1.0 (0.6–1.7)

0.1 % (−44.6–30.9)

Mobile tongue

102/36

2025/1334

1.5 (0.9–2.5)

23.2 % (−13.2–47.9)

Gums

20/10

2025/1334

1.9 (0.6–6.0)

36.1 % (−57.3–74.0)

Floor of mouth

128/38

2025/1334

1.5 (0.9–2.3)

23.6 % (−7.1–45.4)

Soft palate

48/13

2025/1334

4.3 (1.7–10.7)

67.5 % (29.3–85.0)

Other parts of the mouth

55/13

2025/1334

4.2 (1.6–11.1)

67.6 % (24.1–86.2)

 By gender

Male

377/99

1692/928

1.9 (1.4–2.6)

38.0 % (21.3–51.2)

Female

66/51

333/406

1.3 (0.7–2.4)

13.9 % (−18.1–37.3)

 By age

<45

231/172

28/14

2.3 (0.7–7.8)

45.7 % (−37.1–78.5)

45–60

848/561

284/93

1.4 (0.9–2.1)

22.2 % (−3.22–41.2)

>60

946/601

131/43

1.9 (1.3–3.1)

38.2 % (13.0–56.1)