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Table 3 Odds ratio (OR) and corresponding 95 % confidence interval (CI) for urothelial carcinoma of the bladder (UCB), according to indicators of the metabolic syndrome (MetS) in strata of selected variables. Italy, 2003-2014

From: Metabolic syndrome and the risk of urothelial carcinoma of the bladder: a case-control study

Variables

Indicator of MetS

OR (95 % CI)a

χ2 for heterogeneity; p-value

No

Yes

Ca:Co

Ca:Co

Sex

    

  Men

381:359

75:32

2.49 (1.56-3.96)

 

  Women

69:72

8:10

0.81 (0.25-2.60)

3.08; P = 0.08

Age (years)

    

  <65

183:199

25:14

2.53 (1.21-5.29)

 

  ≥65

267:232

58:28

1.97 (1.18-3.29)

0.31; P = 0.59

Education (years)b

    

  <7

178:185

43:24

2.07 (1.14-3.75)

 

  ≥7

271:246

40:18

2.16 (1.17-3.97)

0.01; P = 0.92

Geographical area

    

  North

307:311

64:31

2.31 (1.42-3.74)

 

  South

143:120

19:11

1.56 (0.66-3.67)

0.61; P = 0.43

Smoking habitb

    

  Never

67:150

7:16

1.16 (0.43-3.14)

 

  Ever <20 cig./day

190:174

34:13

2.45 (1.23-4.91)

 

  Ever ≥20 cig./day

186:104

41:13

1.85 (0.93-3.70)

1.37; P = 0.51

Histological subtypeb

    

  Non-papillary

82:431

7:42

0.86 (0.36-2.09)

 

  Papillary

299:431

69:42

2.61 (1.68-4.04)

4.82; P = 0.03

Invasivenessb

    

  pTa/Tis

183:431

41:42

2.32 (1.42-3.79)

 

  pT1-T4

221:431

38:42

2.13 (1.28-3.57)

0.16; P = 0.69

  1. aAdjusted for sex, age (<55; 55-59; 60-64; 65-69; 70-74; ≥75 years), study centre, education (<7; 7-11; ≥12 years), and tobacco smoking (never; former; current: <20; 20+ cigarettes/day); bThe sum does not add up to the total because of missing values