Fig. 3

Relative risk prediction based on quantitative assessment of methylation. a The amount of methylated BCAT1 and IKZF1 as a percentage of total DNA per specimen was used to compute empirical density plots (thin lines) and fitted Gaussian curves (bold lines) from non-cancers (green), early stage cancer (yellow, stage I + II) and late stage cancer (red, stage III + IV). b Relative risk calculations for a given value of methylated BCAT1 and IKZF1 DNA. The minus infinity (-∞) is the log of no methylation (zero values)