Table 3 Multivariate analysis of survival for patients with ANPC
From: Leucopenia and treatment efficacy in advanced nasopharyngeal carcinoma
All population | Cycles <4 population | Cycles > =4 population | ||||
|---|---|---|---|---|---|---|
Variable | OS | DMFS | OS | DMFS | OS | DMFS |
Leucopenia | ||||||
Mild VS Absent | ||||||
HR(95 %CI)a | 0.69(0.56-0.85) | 0.77(0.61-0.96) | 0.70(0.55-0.89) | 0.88(0.63-1.23) | 0.73(0.46-1.15) | 0.61(0.40-0.94) |
P | <0.001 | 0.023 | 0.003 | 0.452 | 0.174 | 0.025 |
Severe VS Absent | ||||||
HR(95 %CI)a | 0.75(0.59-0.95) | 0.99(0.77-1.29) | 0.82(0.60-1.11) | 0.79(0.61-1.03) | 0.97(0.74-1.27) | 0.84(0.53-1.32) |
P | 0.019 | 0.995 | 0.204 | 0.083 | 0.828 | 0.446 |
Mild VS Severe | ||||||
HR(95 %CI)a | 0.93(0.77-1.11) | 0.77(0.64-0.93) | 0.85(0.66-1.09) | 0.90(0.68-1.19 | 0.71(0.46-1.07 | 0.73(0.56-0.96) |
P | 0.416 | 0.006 | 0.204 | 0.469 | 0.108 | 0.026 |
Gender | ||||||
HR(95 %CI) | 0.67(0.55-0.81) | 0.70(0.58-0.86) | 0.66(0.52-0.84) | 0.73(0.57-0.93) | 0.66(0.48-0.91) | 0.68(0.49-0.94) |
P | <0.001 | <0.001 | 0.001 | 0.013 | 0.010 | 0.019 |
Age | ||||||
HR(95 %CI) | 1.82(1.57-2.12) | 1.05(0.89-1.23) | 1.88(1.55-2.28) | 1.09(0.89-1.34 | 1.71(1.34-2.17) | 1.03(0.81-1.33) |
P | <0.001 | 0.532 | <0.001 | 0.367 | <0.001 | 0.783 |
T-classification | ||||||
HR(95 %CI) | 1.49(1.35-1.66) | 1.33(1.19-1.47) | 1.51(1.33-1.72) | 1.36(1.19-1.56) | 1.49(1.26-1.76) | 1.27(1.08-1.51) |
P | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.005 |
N-classification | ||||||
HR(95CI) | 1.77(1.62-1.93) | 1.78(1.62-1.97) | 1.92(1.71-2.16) | 1.92(1.68-2.18) | 1.56(1.35-1.80) | 1.63(1.40-1.90) |
P | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |