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Table 1 Demographics and disease characteristics

From: A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-to-intermediate risk acute myeloid leukemia: results from a randomized, double-blind, phase 2 trial

 

Pegfilgrastim 6 mg

Filgrastim 5 μg/kg/day

No. of Patients

42

41

Age

  

   Median (range), years

51 (18–74)

54 (19–79)

   < 55 years, n (%)

22 (52%)

21 (51%)

   ≥ 55 years, n (%)

20 (48%)

20 (49%)

Male, n (%)

22 (52%)

17 (41%)

Baseline ANC, × 109/L

  

   Mean (SD)

2.2 (5.4)

2.3 (4.0)

   Median (range)

0.4 (0.0–33.8)

1.0 (0.0–17.4)

Most common FAB Type, n (%)

  

   M1

9 (21%)

9 (22%)

   M2

8 (19%)

11 (27%)

   M4

12 (29%)

4 (10%)

   M4eo

3 (7%)

3 (7%)

   M5

4 (10%)

6 (15%)

Cytogenetics, n (%)

  

   Intermediate

34 (81%)

38 (93%)

   Favorable

7 (17%)

3 (7%)

   Unfavorablea

1 (2%)

0 (0%)

Bone marrow cellularity, n (%)

  

   Hypoplastic

4 (10%)

5 (12%)

   Normoplastic

4 (10%)

8 (20%)

   Hyperplastic

33 (79%)

28 (68%)

   Unknown

1 (2%)

0 (0%)

  1. ANC, absolute neutrophil count; SD, standard deviation; FAB, French American British.
  2. aCytogenetic classification re-evaluated after randomization; patient ineligible, but included in analyses consistent with intent-to-treat principles.