A) Representative G-banded metaphases from the OV-1946 (cell 1) cell line. Arrows indicate the abnormal chromosomes, mar: marker chromosome. B) Representative metaphases from OV-1946 (cell 11) cell line analyzed by SKY. The origin of several marker chromosomes (mar) is defined by SKY analysis. Other examples of G-banded metaphases and the combined inverted-DAPI and SKY images of different cells are presented (see additional Files 5).