Figure 5

Quantification of TAM and vascular markers. (A) Representative cytoplasmic expression of MØ marker F4/80 in a MMTV-PyMT tumour section. (B) Total positive staining area of F4/80 was significantly higher in AH than AC treated animals (P < 0.05; *). (C) Representative staining pattern of vascular marker CD31 in MMTV-PyMT tumours. (D) Total CD31 positive area was significantly reduced following hypoxia exposure (P < 0.01; **). AH = acute hypoxia, AC = air control. Bars: mean with SEM. Scale bars: 50 μm.