Morrison PF, Allegra CJ: Folate cycle kinetics in human breast cancer cells. J Biol Chem. 1989, 264 (18): 10552-10566.
CAS
PubMed
Google Scholar
Curtin NJ, Hughes AN: Pemetrexed disodium, a novel antifolate with multiple targets. Lancet Oncol. 2001, 2 (5): 298-306. 10.1016/S1470-2045(00)00325-9.
Article
CAS
PubMed
Google Scholar
Shih C, Habeck LL, Mendelsohn LG, Chen VJ, Schultz RM: Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA). Adv Enzyme Regul. 1998, 38: 135-152. 10.1016/S0065-2571(97)00017-4.
Article
CAS
PubMed
Google Scholar
Yin MB, Guimaraes MA, Zhang ZG, Arredondo MA, Rustum YM: Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor. Cancer Res. 1992, 52 (21): 5900-5905.
CAS
PubMed
Google Scholar
Spiegelman S, Sawyer R, Nayak R, Ritzi E, Stolfi R, Martin D: Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. Proc Natl Acad Sci USA. 1980, 77 (8): 4966-4970.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ross ME, Zhou X, Song G, Shurtleff SA, Girtman K, Williams WK, Liu HC, Mahfouz R, Raimondi SC, Lenny N, Patel A, Downing JR: Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. Blood. 2003, 102 (8): 2951-2959. 10.1182/blood-2003-01-0338.
Article
CAS
PubMed
Google Scholar
Yeoh EJ, Ross ME, Shurtleff SA, Williams WK, Patel D, Mahfouz R, Behm FG, Raimondi SC, Relling MV, Patel A, Cheng C, Campana D, Wilkins D, Zhou X, Li J, Liu H, Pui CH, Evans WE, Naeve C, Wong L, Downing JR: Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. 2002, 1 (2): 133-143. 10.1016/S1535-6108(02)00032-6.
Article
CAS
PubMed
Google Scholar
Jen KY, Cheung VG: Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Res. 2003, 13 (9): 2092-2100. 10.1101/gr.1240103.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zheng PZ, Wang KK, Zhang QY, Huang QH, Du YZ, Zhang QH, Xiao DK, Shen SH, Imbeaud S, Eveno E, Zhao CJ, Chen YL, Fan HY, Waxman S, Auffray C, Jin G, Chen SJ, Chen Z, Zhang J: Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci U S A. 2005
Google Scholar
Oppenheim AV, Willsky AS, Young IT: Signals and Systems. 1983, Prentice Hall, Englewood Cliffs, NJ, 763-763.
Google Scholar
Ihaka R, Gentleman R: R:a language for data analysis and graphics. Journal of Computational and graphical statistics. 1996, 5: 299-314.
Google Scholar
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J: Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004, 5 (10): R80-10.1186/gb-2004-5-10-r80.
Article
PubMed
PubMed Central
Google Scholar
Radivoyevitch T: SBMLR. [http://www.bioconductor.org/repository/devel/package/html/SBMLR.html]
Radivoyevitch T: Radivoyevitch Lab. [http://epbi-radivot.cwru.edu/]
Systems Biology Markup Language. [http://sbml.org]
Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J: The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics. 2003, 19 (4): 524-531. 10.1093/bioinformatics/btg015.
Article
CAS
PubMed
Google Scholar
Finney A, Hucka M: Systems biology markup language: Level 2 and beyond. Biochem Soc Trans. 2003, 31 (Pt 6): 1472-1473.
Article
CAS
PubMed
Google Scholar
Dervieux T, Brenner TL, Hon YY, Zhou Y, Hancock ML, Sandlund JT, Rivera GK, Ribeiro RC, Boyett JM, Pui CH, Relling MV, Evans WE: De novo purine synthesis inhibition and antileukemic effects of mercaptopurine alone or in combination with methotrexate in vivo. Blood. 2002, 100 (4): 1240-1247. 10.1182/blood-2002-02-0495.
Article
CAS
PubMed
Google Scholar
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U: Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet. 2004, 36 (2): 147-150. 10.1038/ng1293.
Article
CAS
PubMed
Google Scholar
Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature. 2000, 404 (6773): 42-49. 10.1038/35003506.
Article
CAS
PubMed
Google Scholar
Kuo ML, Kinsella TJ: Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells. Cancer Res. 1998, 58 (10): 2245-2252.
CAS
PubMed
Google Scholar
Kuo ML, Hwang HS, Sosnay PR, Kunugi KA, Kinsella TJ: Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivity. Cancer J. 2003, 9 (4): 277-285.
Article
CAS
PubMed
Google Scholar
Tai N, Schmitz JC, Liu J, Lin X, Bailly M, Chen TM, Chu E: Translational autoregulation of thymidylate synthase and dihydrofolate reductase. Front Biosci. 2004, 9: 2521-2526.
Article
CAS
PubMed
Google Scholar