Edmondson RJ, Monaghan JM: The epidemiology of ovarian cancer. Int J Gynecol Cancer. 2001, 11: 423-429. 10.1046/j.1525-1438.2001.01053.x.
Article
CAS
PubMed
Google Scholar
Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58,209 women with breast cancer and 101,986 women without the disease. Lancet. 2001, 358: 1389-1399. 10.1016/S0140-6736(01)06524-2.
Pharoah PD, Ponder BA: The genetics of ovarian cancer. Best Pract Res Clin Obstet Gynaecol. 2002, 16: 449-468. 10.1053/beog.2002.0296.
Article
PubMed
Google Scholar
Ponder BA: Cancer genetics. Nature. 2001, 411: 336-341. 10.1038/35077207.
Article
CAS
PubMed
Google Scholar
Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Anglian Breast Cancer Study Group. Br J Cancer. 2000, 83: 1301-1308. 10.1054/bjoc.2000.1407.
Dite GS, Jenkins MA, Southey MC, Hocking JS, Giles GG, McCredie MR, Venter DJ, Hopper JL: Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations. J Natl Cancer Inst. 2003, 95: 448-457.
Article
CAS
PubMed
Google Scholar
Peto J, Collins N, Barfoot R, Seal S, Warren W, Rahman N, Easton DF, Evans C, Deacon J, Stratton MR: Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. J Natl Cancer Inst. 1999, 91: 943-949. 10.1093/jnci/91.11.943.
Article
CAS
PubMed
Google Scholar
Easton DF: How many more breast cancer predisposition genes are there?. Breast Cancer Res. 1999, 1: 14-17. 10.1186/bcr6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pharoah PD, Antoniou A, Bobrow M, Zimmern RL, Easton DF, Ponder BA: Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet. 2002, 31: 33-36. 10.1038/ng853.
Article
CAS
PubMed
Google Scholar
Gayther SA, Russell P, Harrington P, Antoniou AC, Easton DF, Ponder BA: The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes. Am J Hum Genet. 1999, 65: 1021-1029. 10.1086/302583.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T: EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell. 2003, 115: 523-535. 10.1016/S0092-8674(03)00930-9.
Article
CAS
PubMed
Google Scholar
King MC: A novel BRCA2-binding protein and breast and ovarian tumorigenesis. N Engl J Med. 2004, 350: 1252-1253. 10.1056/NEJMcibr033528.
Article
CAS
PubMed
Google Scholar
Livingston DM: EMSY, a BRCA-2 partner in crime. Nat Med. 2004, 10: 127-128. 10.1038/nm0204-127.
Article
CAS
PubMed
Google Scholar
Rodriguez C, Hughes-Davies L, Valles H, Orsetti B, Cuny M, Ursule L, Kouzarides T, Theillet C: Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome. Clin Cancer Res. 2004, 10: 5785-5791.
Article
CAS
PubMed
Google Scholar
Nordling M, Karlsson P, Wahlstrom J, Engwall Y, Wallgren A, Martinsson T: A large deletion disrupts the exon 3 transcription activation domain of the BRCA2 gene in a breast/ovarian cancer family. Cancer Res. 1998, 58: 1372-1375.
CAS
PubMed
Google Scholar
Risch NJ: Searching for genetic determinants in the new millennium. Nature. 2000, 405: 847-856. 10.1038/35015718.
Article
CAS
PubMed
Google Scholar
Tabor HK, Risch NJ, Myers RM: Opinion: Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet. 2002, 3: 391-397. 10.1038/nrg796.
Article
CAS
PubMed
Google Scholar
Rebbeck TR, Ambrosone CB, Bell DA, Chanock SJ, Hayes RB, Kadlubar FF, Thomas DC: SNPs, haplotypes, and cancer: applications in molecular epidemiology. Cancer Epidemiol Biomarkers Prev. 2004, 13: 681-687.
CAS
PubMed
Google Scholar
Freedman ML, Penney KL, Stram DO, Le Marchand L, Hirschhorn JN, Kolonel LN, Altshuler D, Henderson BE, Haiman CA: Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort. Hum Mol Genet. 2004, 13: 2431-2441. 10.1093/hmg/ddh270.
Article
CAS
PubMed
Google Scholar
Cardon LR, Abecasis GR: Using haplotype blocks to map human complex trait loci. Trends Genet. 2003, 19: 135-140. 10.1016/S0168-9525(03)00022-2.
Article
CAS
PubMed
Google Scholar
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D: The structure of haplotype blocks in the human genome. Science. 2002, 296: 2225-2229. 10.1126/science.1069424.
Article
CAS
PubMed
Google Scholar
Pharoah PD, Dunning AM, Ponder BA, Easton DF: Association studies for finding cancer-susceptibility genetic variants. Nat Rev Cancer. 2004, 4: 850-860. 10.1038/nrc1476.
Article
CAS
PubMed
Google Scholar
Gibbs RA, Belmont JW, Hardenbol P, Willis TD, Yu F, Yang H, Ch'ang LY, Huang W, Liu B, Shen Y, Tam PK, Tsui LC, Waye MM, Wong JT, Zeng C, Zhang Q, Chee MS, Galver LM, Kruglyak S, Murray SS, Oliphant AR, Montpetit A, Hudson TJ, Chagnon F, Ferretti V, Leboeuf M, Phillips MS, Verner A, Kwok PY, Duan S, Lind DL, Miller RD, Rice JP, Saccone NL, Taillon-Miller P, Xiao M, Nakamura Y, Sekine A, Sorimachi K, Tanaka T, Tanaka Y, Tsunoda T, Yoshino E, Bentley DR, Deloukas P, Hunt S, Powell D, Altshuler D, Gabriel SB, Zhang H, Matsuda I, Fukushima Y, Macer DR, Suda E, Rotimi CN, Adebamowo CA, Aniagwu T, Marshall PA, Matthew O, Nkwodimmah C, Royal CD, Leppert MF, Dixon M, Stein LD, Cunningham F, Kanani A, Thorisson GA, Chakravarti A, Chen PE, Cutler DJ, Kashuk CS, Donnelly P, Marchini J, McVean GA, Myers SR, Cardon LR, Abecasis GR, Morris A, Weir BS, Mullikin JC, Sherry ST, Feolo M, Altshuler D, Daly MJ, Schaffner SF, Qiu R, Kent A, Dunston GM, Kato K, Niikawa N, Knoppers BM, Foster MW, Clayton EW, Wang VO, Watkin J, Gibbs RA, Belmont JW, Sodergren E, Weinstock GM, Wilson RK, Fulton LL, Rogers J, Birren BW, Han H, Wang H, Godbout M, Wallenburg JC, L'Archeveque P, Bellemare G, Todani K, Fujita T, Tanaka S, Holden AL, Lai EH, Collins FS, Brooks LD, McEwen JE, Guyer MS, Jordan E, Peterson JL, Spiegel J, Sung LM, Zacharia LF, Kennedy K, Dunn MG, Seabrook R, Shillito M, Skene B, Stewart JG, Valle DL, Jorde LB, Belmont JW, Chakravarti A, Cho MK, Duster T, Foster MW, Jasperse M, Knoppers BM, Kwok PY, Licinio J, Long JC, Marshall PA, Ossorio PN, Wang VO, Rotimi CN, Royal CD, Spallone P, Terry SF, Lander ES, Lai EH, Nickerson DA, Altshuler D, Bentley DR, Boehnke M, Cardon LR, Daly MJ, Deloukas P, Douglas JA, Gabriel SB, Hudson RR, Hudson TJ, Kruglyak L, Kwok PY, Nakamura Y, Nussbaum RL, Royal CD, Schaffner SF, Sherry ST, Stein LD, Tanaka T: The International HapMap Project. Nature. 2003, 426: 789-796. 10.1038/nature02168.
Article
CAS
Google Scholar
Dicioccio RA, Song H, Waterfall C, Kimura MT, Nagase H, McGuire V, Hogdall E, Shah MN, Luben RN, Easton DF, Jacobs IJ, Ponder BA, Whittemore AS, Gayther SA, Pharoah PD, Kruger-Kjaer S: STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2004, 13: 1589-1594.
CAS
PubMed
Google Scholar
Day N, Oakes S, Luben R, Khaw KT, Bingham S, Welch A, Wareham N: EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer. Br J Cancer. 1999, 80 Suppl 1: 95-103.
CAS
PubMed
Google Scholar
Stram DO, Haiman CA, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE, Pike MC: Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered. 2003, 55: 27-36. 10.1159/000071807.
Article
PubMed
Google Scholar
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet. 2002, 70: 425-434. 10.1086/338688.
Article
PubMed
Google Scholar
Ding K, Zhou K, He F, Shen Y: LDA--a java-based linkage disequilibrium analyzer. Bioinformatics. 2003, 19: 2147-2148. 10.1093/bioinformatics/btg276.
Article
CAS
PubMed
Google Scholar
Armitage P, Berry G: The size of a statistical investigation. Statistical Methods in Medical Research. 1994, Oxford, Blackwell Scientific Publications, 6.6: 195-206. 3rd edition
Google Scholar
Cox DG, Hankinson SE, Kraft P, Hunter DJ: No association between GPX1 Pro198Leu and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2004, 13: 1821-1822.
CAS
PubMed
Google Scholar
Zondervan KT, Cardon LR: The complex interplay among factors that influence allelic association. Nat Rev Genet. 2004, 5: 89-100. 10.1038/nrg1270.
Article
CAS
PubMed
Google Scholar
Ahmadi KR, Weale ME, Xue ZY, Soranzo N, Yarnall DP, Briley JD, Maruyama Y, Kobayashi M, Wood NW, Spurr NK, Burns DK, Roses AD, Saunders AM, Goldstein DB: A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nat Genet. 2005, 37: 84-89.
Article
CAS
PubMed
Google Scholar
Klein B, Weirich G, Brauch H: DHPLC-based germline mutation screening in the analysis of the VHL tumor suppressor gene: usefulness and limitations. Hum Genet. 2001, 108: 376-384. 10.1007/s004390100500.
Article
CAS
PubMed
Google Scholar
CHEK2*1100delC and Susceptibility to Breast Cancer: A Collaborative Analysis Involving 10,860 Breast Cancer Cases and 9,065 Controls from 10 Studies. Am J Hum Genet. 2004, 74: 1175-1182. 10.1086/421251.
Rebbeck TR, Martinez ME, Sellers TA, Shields PG, Wild CP, Potter JD: Genetic variation and cancer: improving the environment for publication of association studies. Cancer Epidemiol Biomarkers Prev. 2004, 13: 1985-1986.
PubMed
Google Scholar
Colhoun HM, McKeigue PM, Davey SG: Problems of reporting genetic associations with complex outcomes. Lancet. 2003, 361: 865-872. 10.1016/S0140-6736(03)12715-8.
Article
PubMed
Google Scholar
Cui J, Zhou X, Chazaro I, DeStefano AL, Manolis AJ, Baldwin CT, Gavras H: Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites. Am J Hypertens. 2003, 16: 859-863. 10.1016/S0895-7061(03)01026-4.
Article
CAS
PubMed
Google Scholar
Ioannidis JP, Ntzani EE, Trikalinos TA: 'Racial' differences in genetic effects for complex diseases. Nat Genet. 2004, 36: 1312-1318. 10.1038/ng1474.
Article
CAS
PubMed
Google Scholar