Figure 6From: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism MG-132 does not interfere with DNA-PK directly. Lysates of untreated PC-3 cells were incubated with MG-132. There was no decrease in DNA-PK activity, excluding any direct interaction with the drug (n = 3, data expressed as mean ± standard error mean).Back to article page