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Table 1 In vivo orthotopic growth and metastasis of DU145 sublines

From: Identification of genes regulating migration and invasion using a new model of metastatic prostate cancer

Cell line injected

% Tumor incidence

Mean tumor weight (g) (±SD)

Mean tumor diameter (mm) (range)

% Metastatic incidence*

DU145

100

0.66 (0.09)

7.3 (6.3-9.3)

0

DU145-LN1

100

0.99 (0.25)

11.9 (8.3-14.1)

50

DU145-LN2

100

1.80 (0.37)

15.8 (12.9-18.2)

75

DU145-LN3

100

1.16 (0.45)

12.1 (5.5-16.1)

83

DU145-LN4

100

n.d.

10.2 (7.3-12.8)

75

  1. Cells were injected into the prostate. After 5 weeks, tumors and lymph nodes were removed. *K18-positive metastatic foci in lymph nodes. All available lymph nodes were evaluated.