Figure 4From: Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients The effect of DDR2 mutation on lung SCC cells migration and invasion in vitro. HBE, H1703 and SK-MES-1 cells were transfected with pEGFP-DDR2, pEGFP-DDR2-S131C, pEGFP-DDR2-T681I or empty vector. (A, B, C) Transwell assays were used to investigate the changes in migratory and invasive abilities of cells. *P < 0.05 and **P < 0.01.Back to article page