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Figure 2 | BMC Cancer

Figure 2

From: Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients

Figure 2

Detection of DDR2 gene mutation in lung SCC tissues. Conventional Sanger sequencing was performed to analysis the DRR2 gene mutation. (A) In addition to reported DDR2 mutations, three novel DDR2 muatations were found in chinese lung SCC patients. (B, C and D) The S131C mutation was identified in the exon5, G531V and T681I mutations were found in exon13 and exon15, respectively. (E) Analyse of amino acid conservation of DDR2 among human, mouse, and zebrafish homologs.

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