Table 6 Prevalence of biomarker mutations in previous large population studies of lung adenocarcinoma
Molecular biomarker | Author (reference) | Frequency | Total number | Population | Remarks |
|---|---|---|---|---|---|
ALK | Paik et al. [23] | 6.8% | 395 | Korean | Surgically resected |
| Â | Choi et al. [25] | 5.4% | 331 | Korean | Underwent FDG-PET |
| Â | Koh et al. [26] | 20.4% | 221 | Korean | Advanced disease |
| Â | Takeuchi et al. [31] | 3.9% | 1121 | Japanese | Surgically resected |
| Â | Fukui et al. [29] | 3.9% | 720 | Japanese | Surgically resected |
| Â | Wang et al. [32] | 8.6% | 151 | Chinese | Advanced disease |
| Â | Rodig et al. [30] | 5.6% | 358 | American | Surgically resected, partially |
| Â | This study | 2.8% | 217 | Korean | nGGO only |
EGFR | Choi et al. [25] | 47.1% | 331 | Korean | Underwent FDG-PET |
| Â | Kim et al. [46] | 43.5% | 200 | Korean | - |
| Â | Sun et al. [49] | 53.1% | 358 | Korean | - |
| Â | Kosaka et al. [47] | 49.1% | 224 | Japanese | Surgically resected |
| Â | Uramoto et al. [50] | 37.8% | 437 | Japanese | Surgically resected |
| Â | Huang et al. [45] | 38.1% | 858 | Chinese | - |
| Â | Liam et al. [48] | 39.5% | 812 | Malaysian | - |
| Â | This study | 54.8% | 217 | Korean | nGGO only |