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Table 5 Clinicopathological characteristics according to molecular biomarkers in nGGO

From: Epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements in lung cancer with nodular ground-glass opacity

 

EGFR

ALK

P value*

N

119

6

 

Age

63.50 ± 9.11

60.00 ± 12.05

0.571

Sex

M:F = 43:76

M:F = 2:4

0.889

PYR

5.805 ± 14.426

0.750 ± 1.173

0.942

Pathologic stage

117†

6

0.001

  0

6

0

 

  IA

87

1

 

  IB

18

3

 

  IIA

1

1

 

  IIB

2

0

 

  IIIA

3

1

 

  IIIB

0

0

 

Nodal involvement

5

2

0.003

Histologic invasiveness

118**

6

0.351

  AIS

6

0

 

  MIA

11

0

 

  IA

101

6

 

Maximal diameter

22.387 ± 9.876

33.583 ± 13.736

0.032

Solid diameter

11.133 ± 11.229

23.217 ± 16.906

0.032

TDR

0.702 ± 0.295

0.533 ± 0.327

0.225

  1. *P value: EGFR vs. ALK.
  2. †Data for pathologic stage were unavailable for 2 patients.
  3. **Data for histologic invasiveness were unavailable for 1 patient.
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BMC Cancer

ISSN: 1471-2407

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