Table 4 Number and percentage of guideline violations (GV) among non-TNBC and TNBC age subgroups (complete sample, <50, 50–64, and ≥65) stratified for all adjuvant treatment modalities (surgery, chemotherapy, and radiotherapy)

≥1 GV

29.8%

2476/8312

56.0%

473/844

<0.001

GV radiotherapy

8.1%

671/8312

10.0%

84/844

0.059

GV surgery

13.2%

1095/8312

13.5%

114/844

0.785

GV chemotherapy

13.4%

1117/8312

46.6%

393/844

<0.001

Patients < 50

Non-TNBC

TNBC

N = 1,784 (86.3%)

N = 283 (13.7%)

%

N

%

N

p-value

≥1 GV

20.9%

372/1784

42.0%

119/283

<0.001

GV radiotherapy

5.0%

90/1784

7.1%

20/283

0.159

GV surgery

15.8%

281/1784

13.8%

39/283

0.395

GV chemotherapy

1.9%

34/1784

30.0%

85/283

<0.001

Patients 50-64

Non-TNBC

TNBC

N = 3,046 (91.7%)

N = 274 (8.3%)

%

N

%

N

p-value

≥1 GV

25.1%

766/3046

51.1%

140/274

<0.001

GV radiotherapy

5.0%

153/3046

6.6%

18/274

0.267

GV surgery

13.8%

420/3046

14.6%

40/274

0.710

GV chemotherapy

9.2%

281/3046

39.8%

109/274

<0.001

Patients ≥65

Non-TNBC

TNBC

N = 3,482 (92.4%)

N = 287 (7.6%)

%

N

%

N

p-value

≥1 GV

38.4%

1338/3482

74.6%

214/287

<0.001

GV radiotherapy

12.3%

428/3482

16.0%

46/287

0.067

GV surgery

11.3%

394/3482

12.2%

35/287

0.652

GV chemotherapy

23.0%

802/3482

69.3%

199/287

<0.001