Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global Cancer Statistics. CA Cancer J Clin. 2011, 61: 69-90. 10.3322/caac.20107.
Article
PubMed
Google Scholar
Cancer Research UK: UK Oesophageal Cancer Statistics. Cancer Research UK. 2011, Accessed 7-9-2011, [http://www.cancerresearchuk.org/statistics]
Google Scholar
Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE: Long term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol. 2009, 27: 5062-5067. 10.1200/JCO.2009.22.2083.
Article
PubMed
Google Scholar
The National Oesophago-Gastric Cancer Audit: An audit of the care received by people with Oesophago-gastric Cancer in England and Wales. Third Annual Report. 2010, London, NHS Information Centre
Google Scholar
Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson JA, Al-Sarraf M, Byhardt R, Russell AH, Beitler JJ, Spencer S, Asbell SO, Graham MV, Leichman LL: Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospectice randomized trial (RTOG 85-01). Journal of the American Medical Association. 1999, 281 (17): 1623-7. 10.1001/jama.281.17.1623.
CAS
PubMed
Google Scholar
Wong R, Malthaner R: Combined chemotherapy and radiotherapy (without surgery) compared with radiotherapy alone in localized carcinoma of the esophagus. Cochrane Database Systematic Review. 2006, CD002092-
Google Scholar
Bedenne L, Michel P, Bouche O, Triboulet J-P, Conroy T, Pezet D, Roullet B, Seitz J-F, Lacourt J, Milan C: Randomized phase III trial in locally advanced esophageal cancer: radiochemotherapy followed by surgery versus radiochemotherapy alone (FFCD 9102). Proceedings of American Society of Clinical Oncology. 2002, 21: abstr 519-Journal of Oncology
Google Scholar
Gwynne S, Hurt C, Evans M, Holden C, Vout L, Crosby T: Definitive chemoradiation for oesophageal cancer--a standard of care in patients with non-metastatic oesophageal cancer. Clinical Oncology (Royal College of Radiologists (Great Britain)). 2011, 23 (3): 182-188. 10.1016/j.clon.2010.12.001.
Article
CAS
Google Scholar
Denham JW, Steigler A, Kilmurray J, Wratten C, Burmeister B, Lamb DS, Joseph D, Delaney G, Christie D, Jamieson G, Smithers BM, Ackland S, Walpole E: Relapse patterns after chemo-radiation for carcinoma of the oesophagus. Clinical Oncology (Royal College of Radiologists (Great Britain)). 2003, 15 (3): 98-108. 10.1053/clon.2003.0212.
Article
CAS
Google Scholar
Minsky BD, Pajak TF, Ginsberg RJ, Pisansky TM, Martenson J, Komaki R, Okawara G, Rosenthal SA, Kelsen DP: INT 0123 (Radiation Therapy Oncology Groups 94-05) phase III trials of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy. Journal of Clinical Oncology. 2002, 20 (5): 1167-74. 10.1200/JCO.20.5.1167.
Article
CAS
PubMed
Google Scholar
Herskovic A, Martz K, al-Sarraf M, Leichman L, Brindle J, Vaitkevicius V, Cooper J, Byhardt R, Davis L, Emami B: Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. New England Journal of Medicine. 2006, 326 (24): 1593-8.
Article
Google Scholar
Stahl M, Wilke H, Walz MK: A Randomized phase III trial in locally advanced squamous cell carcinoma (SCC) of the esophagus: Chemoradiation with and without surgery. Proceeding of the Annual Meeting of the American Society of Clinical Oncology (ASCO), Journal of Oncology. 2003, 22: abstr 1001-
Google Scholar
Gill V, Melcher A, Crellen A: Chemoradiotherapy for Oesophageal Cancer: The Leeds Cancer Centre Experience. Clinical Oncology (Royal College of Radiologists (Great Britain)). 2003, 15:
Google Scholar
Tsutsumi K, Yasuda M, Nishioka T: X-ray irradiation altered chemosensitivity of a p53-null non-small cell lung cancer cell line. Cell Structure and Function. 2006, 31 (2): 47-52. 10.1247/csf.31.47.
Article
CAS
PubMed
Google Scholar
Byfield JE, Calabro-Jones P, Klisak I, Kulhanian F: Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-Fluorouracil or ftorafur and × rays. International Journal of Radiation Oncology, Biology, Physics. 1982, 8 (11): 1923-33. 10.1016/0360-3016(82)90451-5.
Article
CAS
PubMed
Google Scholar
Button M, Staffurth J, Crosby T: National variations in the treatment of oesophageal carcinoma with chemo-radiotherapy. Clinical Oncology. 2007, 19 (3 Suppl): S25.-
Google Scholar
Cunningham D, Rao S, Starling N, Iveson T, Nicolson M, Coxon F, Middleton G, Daniel F, Oates J, Norman AR, NCRI Upper GI Study Group: Randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric (OG) cancer: The REAL 2 trial. Proceeding of the Annual Meeting of the American Society of Clinical Oncology (ASCO), Journal of Clinical Oncology. 2006, 24: abstrLBA4017-
Google Scholar
Das P, Wolff RA, Abbruzzese JL, Krishnan S, Varadhachary GR, Xiong HQ, Evans DB, Vauthey JN, Baschnagel A, Crane CH: Concurrent capecitabine and upper abdominal radiation therapy is well-tolerated. Proceeding of the American Society of Clinical Oncology (ASCO)GI cancers symposium. Journal of Clinical Oncology. 2006, abstr106-
Google Scholar
Morgan C, Brewster AE, Maughan TS, Harvey-Jones A, Crosby TDL: Patterns of failure after definitive chemo-radiation for inoperable carcinoma of the oesophagus. Clinical Oncology. 2004, 16: S15.2-
Article
Google Scholar
Steel GG: Basic Clinical Radiobiology. Edited by: Gordon Steel G. 2002, 3
Google Scholar
Baumann M, Krause M: Targeting the epidermal growth factor receptor in radiotherapy: radiological mechanism, preclinical and clinical results. Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology. 2004, 72 (3): 257-66. 10.1016/j.radonc.2004.07.007.
Article
CAS
Google Scholar
Schmidt-Ullrich RK, Mikkelsen RB, Dent P, Todd DG, Valerie K, Kavanagh BD, Contessa JN, Rorrer WK, Chen PB: Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene. 1997, 15 (10): 1191-7. 10.1038/sj.onc.1201275.
Article
CAS
PubMed
Google Scholar
Bonner JA, Harari PM, Giralt JL, Azarnia N, Shin DM, Cohen RB, Joes CU, Sur R, Raben D, Jassem J, Ove R, Kies MS, Baselga J, Youssoufian H, Amella N, Rowinsky EK, Ang KK: Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. New England Journal of Medicine. 2006, 354 (6): 567-78. 10.1056/NEJMoa053422.
Article
CAS
PubMed
Google Scholar
Kies MS, Harris J, Rotman MZ, et al: Phase II randomized trial of postoperative chemoradiation plus cetuximab for high-risk squamous cell carcinoma of the head and neck (RTOG 0234). International Journal of Radiation Oncology Biology Physics. 2009, 75 (3): S15-
Article
Google Scholar
Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E: Cetuximab monotherapy and Cetuximab plus irinotecan in irinotecan-refractory metastic colorectal cancer. The New England Journal of Medicine. 2004, 351 (4): 337-45. 10.1056/NEJMoa033025.
Article
CAS
PubMed
Google Scholar
Dewdney A, Capdevila J, Glimelius B, Cervantes A, Tait DM, Brown G, Wotherspoon A, Gonzalez de Castro D, Chua YJ, Wong R, Barbachano Y, Oates JR, Chau I, Cunningham D: EXPERT-C: A randomized, phase II European multicenter trial of neoadjuvant capecitabine plus oxaliplatin chemotherapy (CAPOX) and chemoradiation (CRT) with or without cetuximab followed by total mesorectal excision (TME) in patients with MRI-defined, high-risk rectal cancer. Journal Clinical Oncology. 2011, 29: abstr 3513-
Article
Google Scholar
Rischin D, Burmeister B, Mitchell P, Boyer M, Macmanus M, Walpole E, Feigen M, Tin MM, Ball D: Phase I trial of gefitinib (ZD1839) in combination with concurrent carboplatin, paclitaxel and radiation therapy in patients with stage III non-small cell lung cancer. Journal of Clinical Oncology. 2004, 22 (14S): abstract7077-
Google Scholar
Blumenschein GR, Paulus R, Curran WJ, Robert F, Fossella F, Werner-Wasik M, Herbst RS, Doescher PO, Choy H, Komaki R: Phase II study of cetuximab in combination with chemoradiation in patients with stage IIIA/B non-small-cell lung cancer: RTOG 0324. Journal of Clinical Oncology. 2011, 29 (17): 2312-8. 10.1200/JCO.2010.31.7875.
Article
CAS
PubMed
PubMed Central
Google Scholar
Enzinger PC, Yock T, Suh W, et al: Phase II cisplatin, irinotecan, cetuximab and concurrent radiation therapy followed by surgery for locally advanced esophageal cancer. Journal of Clinical Oncology. 2006, 24 (18): abstr 4064-
Google Scholar
Thomas CR, Goldman BH, Benedetti JK, Lenz HJ, Beeker T, Abbruzzese JL, Blanke CD: Cetuximab plus cisplatin, irinotecan and thoracic radiotherapy (TRT) as definitive treatment for locally advanced, unresectable esophageal cancer (EC): a SWOG (S0414) phase II trial. Proceedings of the. 2010, Orlando, abstract no. 72, Jan 15-17. 2010 (Poster presentation), Gastrointestinal Cancers Symposium
Google Scholar
Suntharalingam M, Dipetrillo T, Akerman P, Wanebo H, Daly B, Doyle LA, Krasna MJ, Kennedy T, Safran H: Cetuximab, paclitaxel, carboplatin and radiation for esophageal and gastric cancer. Proceeding of the Annual Meeting of the American Society of Clinical Oncology (ASCO). Journal of Clinical Oncology. 2006, 24 (18S): Abstr4029-
Google Scholar
Dobelbower MC, Russo SM, Raisch KP, Seay LL, Clemons LK, Suter S, Posey J, Bonner JA: Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: a phase I study. Anticancer Drugs. 2006, 17 (1): 95-102. 10.1097/01.cad.0000185178.26862.4c.
Article
CAS
PubMed
Google Scholar
Gibson MK, Catalano P, Kleinberg LR, Staley CA, Montgomery EA, Song W, Mulcahy MF, Leichman LP, Benson AB: E2205: A phase II study to measure response rate and toxicity of neoadjuvant chemoradiotherapy (CRT) with oxaliplatin (OX) and infusional 5-fluorouracil (5-FU) plus cetuximab (C) followed by postoperative docetaxel (DT) and C in patients with operable adenocarcinoma of the esophagus. Journal of Clinical Oncology. 2010, 28 (15s): Abst.4064-
Google Scholar
Lledo G, Michel P, Dahan L, et al: Chemoradiation with FOLFOX plus cetuximab in locally advanced cardia or esophageal cancer: Final results of a GERCOR phase II trial (ERaFOX). Journal of Clinical Oncology. 2011, 29 (4): abstr 8-
Google Scholar
Lim JT, Truong PT, Berthelet E, Pai H, Joe H, Wai E, Larsson S, Kader HA, Weinerman B, Wilson K, Olivotto IA: Endoscopic response predicts for survivial and organ preservation after primary chemoradiotherapy for esophageal cancer. International Journal of Radiation Oncology, Biology, Physics. 2003, 57 (5): 1328-35. 10.1016/S0360-3016(03)00751-X.
Article
PubMed
Google Scholar
Hui R, Bull CA, Gebski V, O'Rouke I: Radiotherapy and concurrent chemotherapy for oesophageal carcinoma. Australas Radiology. 1994, 38 (4): 315-9. 10.1111/j.1440-1673.1994.tb00208.x.
Article
CAS
Google Scholar
Gill PG, Jamieson GG, Denham J, Devitt PG, Ahmed A, Yeoh E, Jones AM: Treatment of adenocarcinoma of the cardia with synchronous chemotherapy and radiotherapy. British Journal of Surgery. 1990, 77: 1020-1023. 10.1002/bjs.1800770922.
Article
CAS
PubMed
Google Scholar
Bates BA, Detterbeck FC, Bernard SA, Qaqish BF, Tapper JE: Concurrent radiation therapy and chemotherapy followed by esophagectomy for localized esophageal carcinoma. Journal of Clinical Oncology. 1996, 14 (1): 156-63.
CAS
PubMed
Google Scholar
John MJ, Flam MS, Mowry PA, Podolsky WJ, Xavier AM, Wittlinger PS, Padmanabhan A: Radiotherapy alone and chemoradiation for nonmetastatic esophageal carcinoma. A critical review of chemoradiation. Cancer. 1989, 63 (12): 2397-403. 10.1002/1097-0142(19890615)63:12<2397::AID-CNCR2820631204>3.0.CO;2-S.
Article
CAS
PubMed
Google Scholar
Poplin EA, Khanuja PS, Kraut MJ, Herskovic AM, Lattin PB, Cummings G, Gaspar LE, Kinzie JL, Steiger Z, Vaitkevicius VK: Chemoradiotherapy of esophageal carcinoma. Cancer. 1994, 74 (4): 1217-24. 10.1002/1097-0142(19940815)74:4<1217::AID-CNCR2820740407>3.0.CO;2-O.
Article
CAS
PubMed
Google Scholar
Seitz JF, Perrier H, Monges G, Giovannini M, Gouvernet J: Multivariate analysis of the prognostic and predictive factors of response to concomitant radiochemotherapy in epidermoid cancers of the esophagus. Value of immunodetection of protein p53. Gastroenterolgie Clinique et Biologique. 1995, 19 (5): 465-74.
CAS
Google Scholar
Brown WA, Thomas J, Gotley D, Burmeister B, Lim KH, Martin I, Walpole ET, Thomson DB, Harvey JA, Smithers BM: Use of oesophagogastroscopy to assess the response of oesophageal carcinoma to neoadjuvant therapy. British Journal of Surgery. 2004, 91 (2): 199-204. 10.1002/bjs.4411.
Article
CAS
PubMed
Google Scholar
Downey RJ, Akhurst T, Ilson D, Ginsberg R, Bains MS, Gonen M, Koong H, Gollub M, Minsky BD, Zakowski M, Turnbull A, Larson SM, Rusch V: Whole Body 18FDG-PET and the Response of Esophageal Cancer to Induction Therapy: Results of a Prospective Trial. Journal of Clinical Oncology. 2003, 21 (3): 428-32. 10.1200/JCO.2003.04.013.
Article
PubMed
Google Scholar
Barthel FMS, Royston P, Babiker A, UK Medical Research Council: A menu-driven facility for complex sample size calculation in randomized controlled trials with a survival or a binary outcome: update. The Stata Journal. 2005, 5 (1): 129-9.
Google Scholar
Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, Kaasa S, Klee M, Osoba D, Razavi D, Rofe PE, Schraub S, Sneeuw K, Sullivan M, Takeda F: The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. Journal of National Cancer Inst. 1993, 85 (5): 365-376. 10.1093/jnci/85.5.365.
Article
CAS
Google Scholar
Blazeby JM, Conroy T, Hammerlid E, Fayers P, Sezer O, Koller M, Arraras J, Bottomley A, Vickery CW, Etienne PL, Alderson D, European Organisation for Research and Treatment of Cancer Gastrointestinal and Quality of Life Groups: Clinical and psychometric validation of an EORTC questionnaire module, the EORTC QLQ-OES18, to assess quality of life in patients with oesophageal cancer. European Journal of Cancer. 2003, 39 (10): 1384-94. 10.1016/S0959-8049(03)00270-3.
Article
CAS
PubMed
Google Scholar
Finlay AY, Khan GK: Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clinical and Experimental Dermatology. 1994, 19 (3): 210-6. 10.1111/j.1365-2230.1994.tb01167.x.
Article
CAS
PubMed
Google Scholar
Lewis V, Finlay AY: 10 years experience with the dermatology life quality index (DLQI). Journal of the Investigational Dermatological Symposium Porceedings. 2004, 9 (2): 169-80. 10.1111/j.1087-0024.2004.09113.x.
Article
Google Scholar
Fayers P, Aaronson NK, Bjordal K, Groenvold M, Curran D, Bottomley A: EORTC QLQ-C30 Scoring Manual. 2001, 0-86.
Google Scholar