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Table 1 Agreement in classification between microarray-based and microscopic grading in five published data sets

From: A simple method for assigning genomic grade to individual breast tumours

  

Histo-patological grade

Cohort

Genomic grade

G1

G2

G3

Uppsala

G1

63

(93%)

80

(62%)

4

(7.3%)

( N = 251)

G3

5

(7.4%)

48

(38%)

51

(93%)

Stockholm

G1

26

(93%)

44

(76%)

9

(15%)

( N = 147)

G3

2

(7.1%)

14

(24%)

52

(85%)

Guys Hospital

G1

16

(94%)

16

(43%)

0

 

(N = 70)

G3

1

(5.9%)

21

(57%)

16

(100%)

Oxford

G1

15

(83%)

24

(48%)

1

(7.1%)

(N = 82)

G3

3

(17%)

26

(52%)

13

(93%)

NKI

G1

64

(85%)

68

(67%)

31

(26%)

(N = 295)

G3

11

(15%)

33

(33%)

88

(74%)

  1. In bold: concordance in low and high grade (G1 and G3) assignments, describing the accuracy of microarray-based grading. Per cent per column and data set. Genomic grade determined with the optimized signature (reduced from 128 to 91 probe sets) and mean rank. NKI, the Netherlands Cancer Institute.