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Table 2 Univariate and multivariate analysis of baseline predictors of survival in 133 patients with transitional cell carcinoma of the renal pelvis and/or ureter

From: Radiotherapy may improve overall survival of patients with T3/T4 transitional cell carcinoma of the renal pelvis or ureter and delay bladder tumour relapse

Variables n Survival status pvalue Correlation with histology
   3-y 5-y Univariate Multivariate coefficient p
Age       0.130 0.136
   < 60 years 31 66.8 66.8 0.029 0.015   
   ≥ 60 years 102 52.5 37.4     
Sex       0.136 0.119
   Female 50 59.3 48.4 0.402 0.153   
   Male 83 53.6 35.8     
Tumor location       -0.064 0.463
   Renal pelvis 42 59.3 59.3 0.912 0.346   
   Ureter 91 57.0 38.9     
Tumor lesions       0.024 0.785
   Solitary 117 55.0 42.9 0.612 0.340   
   Multiple nodules 16 52.9 26.4     
pT stage       0.404 < 0.001
   T1 or T2 81 76.1 61.6 < 0.001 0.001   
   T3 or T4 52 22.2 16.7     
Synchronous LN       0.143 0.100
   - 124 61.7 47.8 < 0.001 0.002   
   + 9 0 0     
Resection modalities       -0.250 0.004
   Local resection 22 33.7 33.7 0.024 0.178   
   Nephroureterectomy 111 63.4 50.0     
Residual Disease       0.347 < 0.001
   R0 108 65.9 52.2 < 0.001 0.077   
   R1 or R2 25 10.7 10.7     
Histological grade        
   Grade I or II 79 71.1 56.0 < 0.001 0.465   
   Grade III or IV 54 33.2 28.4     
EBRT       0.116 0.182
   No 66 53.6 41.0 0.198 0.024   
   Yes 67 57.5 49.6     
  1. LN: Lymph Node; EBRT: External Beam Radiation Therapy