Table 1 Mutations detected with OncoCarta
ABL1-G250E | EGFR-L747_E749del, A750P | KIT-P585P |
ABL1-Q252H | EGFR-E746_A750del | KIT-D579del |
ABL1-Y253H | EGFR-L747_E749del, A750P | KIT-K642E |
ABL1-Y253F | EGFR-L747_S752del, P753S | KIT-D816V |
ABL1-E255K | EGFR-E746_T751del, V ins | KIT-D816H/D816Y |
ABL1-E255V | EGFR-L747_S752del, Q ins | KIT-V825A |
ABL1-D276G | EGFR-L747_S752del, Q ins | KIT-E839K |
ABL1-F311L | EGFR-E746_T751del, S752D/SNP C2255T | KIT-M552L |
ABL1-T315I | EGFR-D770_N771>AGG/V769_D770insASV/V769_D770insASV | KIT-Y568D |
ABL1-F317L | EGFR-D770_N771insG | KIT-F584S |
ABL1-M351T | EGFR-L747_T750del, P ins | KIT-P551_V555del |
ABL1-E355G | EGFR-E746_A750del | KIT-P551_V555del |
ABL1-F359V | EGFR-E746_T751del, I ins | KIT-Y553_Q556del |
ABL1-H396R | EGFR-L747_T751del | KIT-Y553_Q556del |
AKT1-rs11555435 | EGFR-L747_T751del | KRAS-G12V/A/D/C/S/R/F |
AKT1-rs11555431 | EGFR-E746_A750del, V ins | KRAS-G13C/S/V/D |
AKT1-rs11555432 | EGFR-E746_A750del, V ins | KRAS-A59T |
AKT1-rs12881616 | EGFR-S752_I759del | KRAS-Q61E/K/L/R/P/H |
AKT1-rs11555433 | ERBB2-L755P | MET-R970C |
AKT1-rs11555436 | ERBB2-G776S/G776LC | MET-T992I |
AKT1-rs34409589 | ERBB2-G776VC | MET-Y1230C |
AKT2-S302G | ERBB2-G776VC/G776VC | MET-Y1235D |
AKT2-R371H | ERBB2-M774_A775insYVMA | MET-M1250T |
BRAF-G464R | ERBB2-A775_G776insYVMA | NRAS-G12V/G12A/G12D |
BRAF-G464V/G464E | ERBB2-P780_Y781insGSP | NRAS-G12C/G12R/G12S |
BRAF-G466V/G466G/G466E | ERBB2-P780_Y781insGSP | NRAS-G13V/G13A/G13D |
BRAF-G466R | ERBB2-S779_P780insVGS | NRAS-G13C/G13R/G13S |
BRAF-F468C | FGFR1-S125L | NRAS-A18T |
BRAF-G469S/E/A/V/R | FGFR1-P252T | NRAS-Q61L/Q61R/Q61P |
BRAF-D594V| G | FGFR3-R248C | NRAS-Q61H |
BRAF-F595L | FGFR3-S249C | NRAS-Q61E/Q61K |
BRAF-G596R | FGFR3-G370C | PDGFRA-V561D |
BRAF-L597S/R/Q/V | FGFR3-Y373C | PDGFRA-T674I |
BRAF-T599I | FGFR3-A391E | PDGFRA-F808L |
BRAF-V600E/K/R/L | FGFR3-K650Q/E | PDGFRA-D846Y |
BRAF-K601N/E | FGFR3-K650T/M | PDGFRA-N870S |
CDK-R24C/H | FLT3-I836del | PDGFRA-D1071N |
EGFR-R108K | FLT3_2 | PDGFRA-D842_H845del |
EGFR-T263P | FLT3_3 | PDGFRA-I843_D846del |
EGFR-A289V | FLT3-D835H/D835Y | PDGFRA-S566_E571>K |
EGFR-G598V | HRAS-G12V/D | PDGFRA-I843_S847>T |
EGFR-E709K/E709H | HRAS-G13C/R/S | PDGFRA-D842V |
EGFR-E709A/E709G/E709V | HRAS-G13V/D | PIK3CA-R88Q |
EGFR-G719S/G719C | HRAS-Q61H | PIK3CA-N345K |
EGFR-G719A | HRAS-Q61H/L/R/P/K | PIK3CA-C420R |
EGFR-M766_A767insAI | JAK2-V617F | PIK3CA-P539R |
EGFR-S768I | KIT-D52N | PIK3CA-E542K |
EGFR-V769_D770insASV | KIT-Y503_F504insAY | PIK3CA-E545K |
EGFR-V769_D770insCV | KIT-W557R/W557R/W557G | PIK3CA-Q546K |
EGFR-D770_N771>AGG/V769_D770insASV/V769_D770insASV | KIT-V559D/V559A/V559G | PIK3CA-H701P |
EGFR-D770_N771insG | KIT-V559I | PIK3CA-H1047R/H1047L |
EGFR-N771_P772>SVDNR | KIT-V560D/V560G | PIK3CA-H1047Y |
EGFR-P772_H773insV | KIT-K550_K558del | PIK3CA-G1049R |
EGFR-H773>NPY | KIT-K558_V560del | PIK3CA-R38H |
EGFR-H773_V774insNPH/H773_V774insPH/H773_V774insH | KIT-K558_E562del | PIK3CA-C901F |
EGFR-V774_C775insHV | KIT-V559del | PIK3CA-M1043I/M1043I |
EGFR-T790 M | KIT-V559_V560del | RET-C634R |
EGFR-L858R | KIT-V560del | RET-C634W/Y |
EGFR-L861Q | KIT-Y570_L576del | RET-E632_L633del |
EGFR-L747_T750del, P ins/E746_A750del, T751A | KIT-E561K | RET-M918T |
EGFR-E746_T751del, I ins/S752_I759del | KIT-L576P | RET-A664D |