Skip to main content

Articles

Page 270 of 287

  1. LIM and SH3 protein 1 (LASP-1), initially identified from human breast cancer, is a specific focal adhesion protein involved in cell proliferation and migration, which was reported to be overexpressed in 8–12 ...

    Authors: Thomas GP Grunewald, Ulrike Kammerer, Michaela Kapp, Matthias Eck, Johannes Dietl, Elke Butt and Arnd Honig
    Citation: BMC Cancer 2007 7:198
  2. Despite the fact that morphological and physiological observations suggest that the tight junction (TJ)-based permeability barrier is modified/disrupted in tumorigenesis, the role of members of the Claudin (Cl...

    Authors: Azadeh Arabzadeh, Tammy-Claire Troy and Kursad Turksen
    Citation: BMC Cancer 2007 7:196
  3. The telomeric region of mouse chromosome 12 has previously shown frequent allelic loss in murine lymphoma. The Bcl11b gene has been identified and suggested as a candidate tumor suppressor gene within this region...

    Authors: Anneli Karlsson, Amanda Nordigården, Jan-Ingvar Jönsson and Peter Söderkvist
    Citation: BMC Cancer 2007 7:195
  4. Nasopharyngeal carcinoma is endemic in Southern China, displays a strong relationship with genetic susceptibility and associates with Epstein-Barr virus infection. Toll-like receptor 3 (TLR3) plays an importan...

    Authors: Jun-Fang He, Wei-Hua Jia, Qin Fan, Xin-Xi Zhou, Hai-De Qin, Yin Yao Shugart and Yi-Xin Zeng
    Citation: BMC Cancer 2007 7:194
  5. Colorectal cancer, if detected early, has greater than 90% 5-year survival. However, survival has been shown to vary across racial/ethnic groups in the United States, despite the availability of early detectio...

    Authors: Scarlett Lin Gomez, Cynthia D O'Malley, Antoinette Stroup, Sarah J Shema and William A Satariano
    Citation: BMC Cancer 2007 7:193
  6. It has recently been shown that NDRG2 mRNA is down-regulated or undetectable in several human cancers and cancer cell-lines. Although the function of NDRG2 is unknown, high NDRG2 expression correlates with improv...

    Authors: Anders Lorentzen, Lotte K Vogel, Rikke H Lewinsky, Mona Sæbø, Camilla F Skjelbred, Sine Godiksen, Geir Hoff, Kjell M Tveit, Inger Marie Bowitz Lothe, Tone Ikdahl, Elin H Kure and Cathy Mitchelmore
    Citation: BMC Cancer 2007 7:192
  7. A verifiable consequence of the mutator hypothesis is that even low grade neoplasms would accumulate a large number of mutations that do not influence the tumor phenotype (clonal mutations). In this study, we ...

    Authors: Anjan Misra, Parthaprasad Chattopadhyay, Kunzang Chosdol, Chitra Sarkar, Ashok K Mahapatra and Subrata Sinha
    Citation: BMC Cancer 2007 7:190
  8. Matrix metalloproteinase (MMP) is known to be involved in the initial and progressive stages of cancer development, and in the aggressive phenotypes of cancer. This study examines the association of single nucleo...

    Authors: Rishiho Nishizawa, Masaki Nagata, Arhab A Noman, Nobutaka Kitamura, Hajime Fujita, Hideyuki Hoshina, Takehiko Kubota, Manami Itagaki, Susumu Shingaki, Makoto Ohnishi, Hiroshi Kurita, Kouji Katsura, Chikara Saito, Hiromasa Yoshie and Ritsuo Takagi
    Citation: BMC Cancer 2007 7:187
  9. A set of consistent, standardized definitions of intervals and populations on which to report across provinces is needed to inform the Provincial/Territorial Deputy Ministries of Health on progress of the Ten-...

    Authors: Marcy Winget, Donna Turner, Jon Tonita, Charlotte King, Zoann Nugent, Riaz Alvi and Richard Barss
    Citation: BMC Cancer 2007 7:186
  10. Lymphomatous meningitis (LM) represents a severe complication of malignant lymphomas. While clinical suspicion is raised by symptoms ranging from mild disturbances of sensation to severe pain or impaired consc...

    Authors: B Hildebrandt, C Müller, A Pezzutto, PT Daniel, B Dörken and C Scholz
    Citation: BMC Cancer 2007 7:185
  11. Despite significant advancement in breast cancer therapy, there is a great need for a better understanding of the mechanisms involved in breast carcinogenesis and progression, as well as of the role of epigene...

    Authors: Esteban N Gurzov, Sanaa M Nabha, Hamilto Yamamoto, Hong Meng, O Graciela Scharovsky and R Daniel Bonfil
    Citation: BMC Cancer 2007 7:184
  12. Dietary isothiocyanates (ITCs) are electrophilic compounds that have diverse biological activities including induction of apoptosis and effects on cell cycle. They protect against experimental carcinogenesis i...

    Authors: Janet V Cross, Frank W Foss, Joshua M Rady, Timothy L Macdonald and Dennis J Templeton
    Citation: BMC Cancer 2007 7:183
  13. Published prognostic gene signatures in breast cancer have few genes in common. Here we provide a rationale for this observation by studying the prognostic power and the underlying biological pathways of diffe...

    Authors: Jack X Yu, Anieta M Sieuwerts, Yi Zhang, John WM Martens, Marcel Smid, Jan GM Klijn, Yixin Wang and John A Foekens
    Citation: BMC Cancer 2007 7:182
  14. The sex hormone estrogen (E2) is pivotal to normal mammary gland growth and differentiation and in breast carcinogenesis. In this in silico study, we examined metabolic differences between ER(+)ve breast cancer c...

    Authors: Soma Mandal and James R Davie
    Citation: BMC Cancer 2007 7:181
  15. Feline mammary carcinoma has been proposed as a natural model of highly aggressive, hormone-independent human breast cancer. To further explore the utility of the model by adding new similarities between the t...

    Authors: Javier Ordás, Yolanda Millán, Rafaela Dios, Carlos Reymundo and Juana Martín de las Mulas
    Citation: BMC Cancer 2007 7:179
  16. For patients suffering of recurrent breast cancer within the irradiated breast, generally mastectomy is recommended. The normal tissue tolerance does not permit a second full-dose course of radiotherapy to the...

    Authors: Uta Kraus-Tiefenbacher, Lelia Bauer, Antonella Scheda, Carola Schoeber, Joerg Schaefer, Volker Steil and Frederik Wenz
    Citation: BMC Cancer 2007 7:178
  17. The present study evaluates the outcome of 19 children with rhabdomyosarcoma of the head-and-neck region treated with Intensity Modulated Radiotherapy (IMRT) or Fractionated Stereotactic Radiotherapy (FSRT) be...

    Authors: Stephanie E Combs, Wolfgang Behnisch, Andreas E Kulozik, Peter E Huber, Jürgen Debus and Daniela Schulz-Ertner
    Citation: BMC Cancer 2007 7:177
  18. Interleukin-8 (IL-8) is a cytokine that plays an important role in tumor progression in a variety of cancer types; however, its regulation is not well understood in oral cancer cells. In the present study, we ...

    Authors: Hwa-Jeong Lee, Jun Lee, Sun-Kyung Lee, Suk-Keun Lee and Eun-Cheol Kim
    Citation: BMC Cancer 2007 7:176
  19. Previously, 50% of patients with breast ductal carcinoma in situ (DCIS) had more than one nuclear grade, and neither worst nor predominant nuclear grade was significantly associated with development of invasive c...

    Authors: Judith-Anne W Chapman, Naomi A Miller, H Lavina A Lickley, Jin Qian, William A Christens-Barry, Yuejiao Fu, Yan Yuan and David E Axelrod
    Citation: BMC Cancer 2007 7:174
  20. The host immunogenetic background plays an important role in the development of breast cancer. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a molecule expressed predominantly on activated T cells and is import...

    Authors: Lihong Wang, Dalin Li, Zhenkun Fu, Heng Li, Wei Jiang and Dianjun Li
    Citation: BMC Cancer 2007 7:173
  21. The prognosis of patients with hepatocellular carcinoma (HCC) still remains very dismal, which is mainly due to metastasis. In our previous studies, we found that chromosome 8p deletions might contribute to me...

    Authors: Ke-Feng Lei, Yan-Fang Wang, Xiao-Qun Zhu, Peng-Cheng Lu, Bing-Sheng Sun, Hu-Liang Jia, Ning Ren, Qing-Hai Ye, Hui-Chuan Sun, Lu Wang, Zhao-You Tang and Lun-Xiu Qin
    Citation: BMC Cancer 2007 7:172
  22. Contrast enhanced ultrasound (CEUS) is an imaging technique which appeared on the market around the year 2000 and proposed for the detection of liver metastases in gastrointestinal cancer patients, a setting i...

    Authors: Fabio Piscaglia, Francesco Corradi, Mikaela Mancini, Francesco Giangregorio, Stefano Tamberi, Giampaolo Ugolini, Bruno Cola, Alberto Bazzocchi, Roberto Righini, Patrizia Pini, Fabio Fornari and Luigi Bolondi
    Citation: BMC Cancer 2007 7:171
  23. Male breast cancer (MBC) is a rare disease and little is known about its aetiology. Germ-line mutations of BRCA2 and, at lower frequency, of BRCA1 are implicated in a relatively small proportion of MBC cases. Com...

    Authors: Domenico Palli, Mario Falchetti, Giovanna Masala, Ramona Lupi, Francesco Sera, Calogero Saieva, Cristina D'Amico, Marco Ceroti, Piera Rizzolo, Maria Adelaide Caligo, Ines Zanna and Laura Ottini
    Citation: BMC Cancer 2007 7:170
  24. The functional and clinical significance of 14-3-3 proteins in human cancers remain largely undetermined. Earlier, we have reported differential expression of 14-3-3ζ mRNA in oral squamous cell carcinoma (OSCC...

    Authors: Ajay Matta, Sudhir Bahadur, Ritu Duggal, Siddhartha D Gupta and Ranju Ralhan
    Citation: BMC Cancer 2007 7:169
  25. p53 is commonly inactivated by mutations in the DNA-binding domain in a wide range of cancers. As mutant p53 often influences response to therapy, effective and rapid methods to scan for mutations in TP53 are lik...

    Authors: Michael Krypuy, Ahmed Ashour Ahmed, Dariush Etemadmoghadam, Sarah J Hyland, Anna deFazio, Stephen B Fox, James D Brenton, David D Bowtell and Alexander Dobrovic
    Citation: BMC Cancer 2007 7:168
  26. Many patients suffer from severe shoulder complaints after breast cancer surgery and axillary lymph node dissection. Physiotherapy has been clinically observed to improve treatment of these patients. However, ...

    Authors: Carien HG Beurskens, Caro JT van Uden, Luc JA Strobbe, Rob AB Oostendorp and Theo Wobbes
    Citation: BMC Cancer 2007 7:166
  27. Inflammatory cells in the tumour stroma has gained increasing interest recently. Thus, we aimed to study the frequency and prognostic impact of stromal mast cells and tumour infiltrating eosinophils in invasiv...

    Authors: Rose-Marie Amini, Kirsimari Aaltonen, Heli Nevanlinna, Ricardo Carvalho, Laura Salonen, Päivi Heikkilä and Carl Blomqvist
    Citation: BMC Cancer 2007 7:165
  28. Polymorphisms in DNA repair genes have been associated to repair DNA lesions, and might contribute to the individual susceptibility to develop different types of cancer. Nucleotide excision repair (NER), base ...

    Authors: M Felicitas López-Cima, Patricia González-Arriaga, Laura García-Castro, Teresa Pascual, Manuel G Marrón, Xose S Puente and Adonina Tardón
    Citation: BMC Cancer 2007 7:162
  29. Induction of apoptosis is one strategy for treatment of prostate cancer. The Shb adapter protein has been found to regulate apoptosis in various cell types and consequently human prostate cancer 3 (PC3) cells ...

    Authors: Padideh Davoodpour, Maréne Landström and Michael Welsh
    Citation: BMC Cancer 2007 7:161
  30. Young women presenting with breast cancer are more likely to have a genetic predisposition to the disease than breast cancer patients in general. A genetic predisposition is known to increase the risk of new p...

    Authors: Diana Eccles, Sue Gerty, Peter Simmonds, Victoria Hammond, Sarah Ennis and Douglas G Altman
    Citation: BMC Cancer 2007 7:160
  31. Interferon-α (IFN-α) is one of the central agents in immunotherapy for renal cell carcinoma (RCC) and binds to the IFN-α receptor (IFNAR). We investigated the role of IFNAR in RCC.

    Authors: Takao Kamai, Yoshiaki Yanai, Kyoko Arai, Hideyuki Abe, Tomonori Yamanishi, Masashi Kurimoto and Ken-Ichiro Yoshida
    Citation: BMC Cancer 2007 7:159
  32. Interferons are a group of proteins that trigger multiple responses including prevention of viral replication, inhibition of cell growth, and modulation of cell differentiation. In different mammary carcinoma ...

    Authors: Ignacio García-Tuñón, Mónica Ricote, Antonio Ruiz A, Benito Fraile, Ricardo Paniagua and Mar Royuela
    Citation: BMC Cancer 2007 7:158
  33. Adenoid Cystic Carcinoma (ACC) is a rare tumor entity and comprises about 1% of all malignant tumor of the oral and maxillofacial region. It is slow growing but a highly invasive cancer with a high recurrence ...

    Authors: Amal Abdul-Hussein, Pierre A Morris and Tsveti Markova
    Citation: BMC Cancer 2007 7:157
  34. Histological phenotype and clinical behaviour of malignant tumours are not only dependent on alterations in the epithelial cell compartment, but are affected by their interaction with inflammatory cells and tu...

    Authors: David Bacman, Susanne Merkel, Roland Croner, Thomas Papadopoulos, Wolfgang Brueckl and Arno Dimmler
    Citation: BMC Cancer 2007 7:156
  35. Combination of platinum derivatives with paclitaxel is currently the standard front line regimen for patients with epithelial ovarian carcinoma, and represents also an active regimen in patients with metastati...

    Authors: Bohuslav Melichar, Radomír Hyšpler, Emanuela Dragounová, Josef Dvořák, Hana Kalábová and Alena Tichá
    Citation: BMC Cancer 2007 7:155
  36. Colorectal cancer (CRC) diagnosis and the ensuing treatments can have a substantial impact on the physical and psychological health of survivors. As the number of CRC survivors increases, so too does the need ...

    Authors: Rosalind R Spence, Kristiann C Heesch, Elizabeth G Eakin and Wendy J Brown
    Citation: BMC Cancer 2007 7:154
  37. Breast cancer is the most common cancer in women in the U.S. and Western Europe. Amplification of the her-2/neu gene occurs in approximately 25% of invasive ductal carcinomas of the breast. The first HER-2/neu...

    Authors: Gustavo A Viani, Sergio L Afonso, Eduardo J Stefano, Ligia I De Fendi and Francisco V Soares
    Citation: BMC Cancer 2007 7:153
  38. Erlotinib is a Human Epidermal Growth Factor Receptor Type 1/tyrosine kinase (EGFR) inhibitor which is used for non-small-cell lung cancer treatment. Despite that erlotinib is considered to have a favorable sa...

    Authors: Demosthenes Makris, Arnaud Scherpereel, Marie Christine Copin, Guillaume Colin, Luc Brun, Jean Jacques Lafitte and Charles Hugo Marquette
    Citation: BMC Cancer 2007 7:150
  39. The use of combined positron emission tomography/computerised tomography (PET/CT) scanners in oncology has been shown to improve the staging of tumours and the detection of relapses. However, mis-registration ...

    Authors: Jayson Wang, Gary Cook, John Frank, Roberto Dina, Naomi Livni, John Lynn, William Fleming and Michael J Seckl
    Citation: BMC Cancer 2007 7:147

Featured videos

View featured videos from across the BMC-series journals