Skip to main content

Articles

Page 250 of 284

  1. Tumor-specific cytotoxic T cells and infiltrating lymphocytes are frequently found in tumor tissues in patients with nasopharyngeal carcinoma (NPC). Most patients with NPC, however, especially those with advan...

    Authors: Peng Liu, Bai-Lu Xie, Shao-Hui Cai, Yun-Wen He, Ge Zhang, Yan-Mei Yi and Jun Du
    Citation: BMC Cancer 2009 9:416
  2. Broccoli is a Brassica vegetable that is believed to possess chemopreventive properties. Selenium also shows promise as an anticancer agent. Thus, selenium enrichment of broccoli has the potential to enhance t...

    Authors: Rizky Abdulah, Ahmad Faried, Kenji Kobayashi, Chiho Yamazaki, Eka W Suradji, Kazuto Ito, Kazuhiro Suzuki, Masami Murakami, Hiroyuki Kuwano and Hiroshi Koyama
    Citation: BMC Cancer 2009 9:414
  3. Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in KIT or PDGFRA of the type III receptor tyrosine kinase fami...

    Authors: Jerzy Ostrowski, Marcin Polkowski, Agnieszka Paziewska, Magdalena Skrzypczak, Krzysztof Goryca, Tymon Rubel, Katarzyna Kokoszyñska, Piotr Rutkowski, Zbigniew I Nowecki, Anna Jerzak Vel Dobosz, Dorota Jarosz, Wlodzimierz Ruka and Lucjan S Wyrwicz
    Citation: BMC Cancer 2009 9:413
  4. Pancreatic cancer is an extremely aggressive malignancy. Subjects are afflicted with a variety of disconcerting symptoms, including profound cachexia. Recent data indicate that the outcome of oncological patie...

    Authors: Angela Märten, Moritz N Wente, Jennifer Ose, Markus W Büchler, Ingeborg Rötzer, Christiane Decker-Baumann, Irini Karapanagiotou-Schenkel, Sabine Harig, Jan Schmidt and Dirk Jäger
    Citation: BMC Cancer 2009 9:412
  5. c-Met is a tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF), and both c-Met and its ligand are expressed in a variety of tissues. C-Met/HGF/SF signaling is essential for normal emb...

    Authors: Hal E Crosswell, Anindya Dasgupta, Carlos S Alvarado, Tanya Watt, James G Christensen, Pradip De, Donald L Durden and Harry W Findley
    Citation: BMC Cancer 2009 9:411
  6. Y-box binding protein-1 (YB-1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus YB-1 protein orchestrates transcription of proliferation-relat...

    Authors: Edgar Dahl, Abdelaziz En-Nia, Frank Wiesmann, Renate Krings, Sonja Djudjaj, Elisabeth Breuer, Thomas Fuchs, Peter J Wild, Arndt Hartmann, Sandra E Dunn and Peter R Mertens
    Citation: BMC Cancer 2009 9:410
  7. Protracted low-dose concurrent chemotherapy combined with radiation has been proposed for enhanced treatment results for esophageal cancer. We evaluated the efficacy and the toxicity of a novel regimen of dail...

    Authors: Satoshi Osawa, Takahisa Furuta, Ken Sugimoto, Takashi Kosugi, Tomohiro Terai, Mihoko Yamade, Yasuhiro Takayanagi, Masafumi Nishino, Yasushi Hamaya, Chise Kodaira, Takanori Yamada, Moriya Iwaizumi, Kosuke Takagaki, Ken-ichi Yoshida, Shigeru Kanaoka and Mutsuhiro Ikuma
    Citation: BMC Cancer 2009 9:408
  8. The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of various carcinogens, including heterocyclic amines (HCA) an...

    Authors: Vibeke Andersen, Mette Østergaard, Jane Christensen, Kim Overvad, Anne Tjønneland and Ulla Vogel
    Citation: BMC Cancer 2009 9:407
  9. The Int7G24A variant of transforming growth factor-beta receptor type I (TGFBR1) has been shown to increase the risk for kidney, ovarian, bladder, lung and breast cancers. Its role in colorectal cancer (CRC) has ...

    Authors: Adela Castillejo, Trinidad Mata-Balaguer, Carla Guarinos, María-Isabel Castillejo, Ana Martínez-Cantó, Víctor-Manuel Barberá, Paola Montenegro, Enrique Ochoa, Rafael Lázaro, Carmen Guillén-Ponce, Alfredo Carrato and José-Luís Soto
    Citation: BMC Cancer 2009 9:406
  10. Depending on the population studied, large genomic rearrangements (LGRs) of the mismatch repair (MMR) genes constitute various proportions of the germline mutations that predispose to hereditary non-polyposis col...

    Authors: Katarina Zavodna, Tomas Krivulcik, Maria Gerykova Bujalkova, Tomas Slamka, David Martinicky, Denisa Ilencikova and Zdena Bartosova
    Citation: BMC Cancer 2009 9:405
  11. It has been speculated that the biostimulatory effect of Low Level Laser Therapy could cause undesirable enhancement of tumor growth in neoplastic diseases. The aim of the present study is to analyze the behav...

    Authors: Lúcio Frigo, Juliana SS Luppi, Giovani M Favero, Durnavei A Maria, Sócrates C Penna, Jan M Bjordal, Rene J Bensadoun and Rodrigo AB Lopes-Martins
    Citation: BMC Cancer 2009 9:404
  12. The seroprevalence of IgG antibodies of Streptococcus gallolyticus subspecies gallolyticus, CIP 105428, was evaluated to investigate the controversial association of S. gallolyticus with colorectal carcinoma and ...

    Authors: Ahmed S Abdulamir, Rand R Hafidh, Layla K Mahdi, Tarik Al-jeboori and Fatimah Abubaker
    Citation: BMC Cancer 2009 9:403
  13. Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is frequently over-expressed in simple epithelia, progenitors, embryonic and tissue stem cells, carcinoma and cancer-initiating ce...

    Authors: Sabine Denzel, Dorothea Maetzel, Brigitte Mack, Carola Eggert, Gabriele Bärr and Olivier Gires
    Citation: BMC Cancer 2009 9:402
  14. Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate ...

    Authors: Aaron L Sarver, Amy J French, Pedro M Borralho, Venugopal Thayanithy, Ann L Oberg, Kevin AT Silverstein, Bruce W Morlan, Shaun M Riska, Lisa A Boardman, Julie M Cunningham, Subbaya Subramanian, Liang Wang, Tom C Smyrk, Cecilia MP Rodrigues, Stephen N Thibodeau and Clifford J Steer
    Citation: BMC Cancer 2009 9:401
  15. Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of hepatocellular carcinoma (HCC) related to the exposure of aflatoxin B1 ...

    Authors: Xi Dai Long, Yun Ma, Yun Feng Zhou, Jin Guang Yao, Fu Zhi Ban, Yong Zhi Huang and Bing Cheng Huang
    Citation: BMC Cancer 2009 9:400
  16. Drug resistance is a primary hindrance for the efficiency of chemotherapy against osteosarcoma. Although chemotherapy has improved the prognosis of osteosarcoma patients dramatically after introduction of neo-...

    Authors: Michiro Susa, Arun K Iyer, Keinosuke Ryu, Francis J Hornicek, Henry Mankin, Mansoor M Amiji and Zhenfeng Duan
    Citation: BMC Cancer 2009 9:399
  17. Etoposide is currently one of the most commonly used antitumor drugs. The mechanisms of action proposed for its antitumor activity are based mainly on its interaction with topoisomerase II. Etoposide effects i...

    Authors: Emilio Rojas, Patricia Mussali, Efrain Tovar and Mahara Valverde
    Citation: BMC Cancer 2009 9:398
  18. Polymorphisms in glutathione S-transferase (GST) genes may influence response to oxidative stress and modify prostate cancer (PCA) susceptibility. These enzymes generally detoxify endogenous and exogenous agents,...

    Authors: Nicole A Lavender, Marnita L Benford, Tiva T VanCleave, Guy N Brock, Rick A Kittles, Jason H Moore, David W Hein and La Creis R Kidd
    Citation: BMC Cancer 2009 9:397
  19. The Specialized Program of Research Excellence (SPORE) in Head and Neck Cancer neoplasm virtual biorepository is a bioinformatics-supported system to incorporate data from various clinical, pathological, and m...

    Authors: Waqas Amin, Hyunseok P Kang, Ann Marie Egloff, Harpreet Singh, Kerry Trent, Jennifer Ridge-Hetrick, Raja R Seethala, Jennifer Grandis and Anil V Parwani
    Citation: BMC Cancer 2009 9:396
  20. The strong association between aberrant HDAC activity and the occurrence of cancer has led to the development of a variety of HDAC inhibitors (HDIs), which emerge as promising new targeted anticancer therapeut...

    Authors: Annika Lehmann, Carsten Denkert, Jan Budczies, Ann-Christin Buckendahl, Silvia Darb-Esfahani, Aurelia Noske, Berit Maria Müller, Marcus Bahra, Peter Neuhaus, Manfred Dietel, Glen Kristiansen and Wilko Weichert
    Citation: BMC Cancer 2009 9:395
  21. B7-H4, a co-inhibitory molecule of the B7 family, can restrain T cell proliferation, cytokine secretion and the development of cytotoxicity. B7-H4 is expressed in tumor tissues at a higher level than in normal...

    Authors: Jie Zhang, Mingyan Zhang, Wei Jiang, Lihong Wang, Zhenkun Fu, Dalin Li, Da Pang and Dianjun Li
    Citation: BMC Cancer 2009 9:394
  22. Chondroblastoma is a benign cartilaginous tumour of bone that predominantly affects the epiphysis of long bones in young males. No recurrent chromosomal re-arrangements have so far been observed. Methods: We i...

    Authors: Salvatore Romeo, Karoly Szuhai, Isao Nishimori, Marije Ijszenga, Pauline Wijers-Koster, Antonie HM Taminiau and Pancras CW Hogendoorn
    Citation: BMC Cancer 2009 9:393
  23. Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising agent for human cancer therapy, prostate cancer still remains resistant to TRAIL. Both X-linked inhibitor of apoptosis (X...

    Authors: Yao Dai, Meilan Liu, Wenhua Tang, Yongming Li, Jiqin Lian, Theodore S Lawrence and Liang Xu
    Citation: BMC Cancer 2009 9:392
  24. Information on the biology of metastasis development in salivary gland tumors is scarce. Since angiogenesis seems associated with this phenomenon in other tumors, we sought to compare salivary gland tumors wit...

    Authors: Sergio V Cardoso, Kelen Christine N Souza, Paulo R Faria, Ana Lucia A Eisenberg, Fernando L Dias and Adriano M Loyola
    Citation: BMC Cancer 2009 9:391
  25. Recent evidence suggests that neutrophil gelatinase-associated lipocalin (NGAL) expression is induced in many types of human cancer, while detection of its complex with matrix metalloproteinase-9 (MMP-9) is co...

    Authors: Xeni Provatopoulou, Antonia Gounaris, Eleni Kalogera, Flora Zagouri, Ioannis Flessas, Evgenios Goussetis, Afroditi Nonni, Ioannis Papassotiriou and George Zografos
    Citation: BMC Cancer 2009 9:390
  26. Surgical resection is one important curative treatment for hepatocellular carcinoma (HCC), but the prognosis following surgery differs substantially and such large variation is mainly unexplained. A review of ...

    Authors: Ke Hao, John M Luk, Nikki PY Lee, Mao Mao, Chunsheng Zhang, Mark D Ferguson, John Lamb, Hongyue Dai, Irene O Ng, Pak C Sham and Ronnie TP Poon
    Citation: BMC Cancer 2009 9:389
  27. Well-differentiated neuroendocrine carcinomas are highly vascularized and may be sensitive to drugs administered on a metronomic schedule that has shown antiangiogenic properties. A phase II study was designed...

    Authors: Maria P Brizzi, Alfredo Berruti, Anna Ferrero, Enrica Milanesi, Marco Volante, Federico Castiglione, Nadia Birocco, Sebastiano Bombaci, Davide Perroni, Benedetta Ferretti, Oscar Alabiso, Libero Ciuffreda, Oscar Bertetto, Mauro Papotti and Luigi Dogliotti
    Citation: BMC Cancer 2009 9:388
  28. Thyroid carcinomas show a high prevalence of mutations in the oncogene BRAF which are inversely associated with RAS or RET/PTC oncogenic activation. The possibility of using inhibitors on the BRAF pathway as b...

    Authors: Ana Preto, Joana Gonçalves, Ana P Rebocho, Joana Figueiredo, Ana M Meireles, Ana S Rocha, Helena M Vasconcelos, Hugo Seca, Raquel Seruca, Paula Soares and Manuel Sobrinho-Simões
    Citation: BMC Cancer 2009 9:387
  29. Her2/neu is overexpressed in various human cancers of epithelial origin and is associated with increased metastatic potential and poor prognosis. Several attempts have been made using the extracellular domain ...

    Authors: Alexios Dimitriadis, Chrysanthi Gontinou, Constantin N Baxevanis and Avgi Mamalaki
    Citation: BMC Cancer 2009 9:386
  30. Egr-1 (early growth response-1 transcription factor) has been proposed to be involved in invasion and metastasis processes of human bladder cancer, but Egr-1 protein expression levels in human bladder cancer h...

    Authors: Frederikke Lihme Egerod, Annette Bartels, Niels Fristrup, Michael Borre, Torben F Ørntoft, Martin B Oleksiewicz, Nils Brünner and Lars Dyrskjøt
    Citation: BMC Cancer 2009 9:385
  31. Decay-accelerating factor (DAF) and membrane cofactor protein (MCP) are the key molecules involved in cell protection against autologus complement, which restricts the action of complement at critical stages o...

    Authors: Ling-Juan Gao, Shu-Yu Guo, You-Qun Cai, Ping-Qing Gu, Ya-Juan Su, Hui Gong, Yun Liu and Chen Chen
    Citation: BMC Cancer 2009 9:384
  32. Testicular germ cell tumors (TGCTs) are classified as seminonas or non-seminomas of which a major subset is embryonal carcinoma (EC) that can differentiate into diverse tissues. The pluripotent nature of human...

    Authors: Grace E Snow, Allison C Kasper, Alexander M Busch, Elisabeth Schwarz, Katherine E Ewings, Thomas Bee, Michael J Spinella, Ethan Dmitrovsky and Sarah J Freemantle
    Citation: BMC Cancer 2009 9:383
  33. Loss of DNA mismatch repair (MMR) in humans, mainly due to mutations in the hMLH1 gene, is linked to hereditary nonpolyposis colorectal cancer (HNPCC). Because not all MLH1 alterations result in loss of MMR funct...

    Authors: Matjaz Vogelsang, Aleksandra Comino, Neja Zupanec, Petra Hudler and Radovan Komel
    Citation: BMC Cancer 2009 9:382
  34. Patterns in survival can provide information about the burden and severity of cancer, help uncover gaps in systemic policy and program delivery, and support the planning of enhanced cancer control systems. The...

    Authors: Alireza Sadjadi, T Gregory Hislop, Chris Bajdik, Morteza Bashash, Anahita Ghorbani, Mehdi Nouraie, Masoud Babaei, Reza Malekzadeh and Parvin Yavari
    Citation: BMC Cancer 2009 9:381
  35. The transient receptor potential, subfamily V, member 6 (TRPV6) is a Ca2+ selective cation channel. Several studies have shown that TRPV6 transcripts are expressed in locally advanced prostatic adenocarcinoma, me...

    Authors: Thorsten Kessler, Ulrich Wissenbach, Rainer Grobholz and Veit Flockerzi
    Citation: BMC Cancer 2009 9:380
  36. A genome-wide association study (GWAS), which assessed multiple ethnicities, reported an association between single nucleotide polymorphisms in the 8q24 region and colorectal cancer risk. Although the associat...

    Authors: Keitaro Matsuo, Takeshi Suzuki, Hidemi Ito, Satoyo Hosono, Takakazu Kawase, Miki Watanabe, Kohei Shitara, Koji Komori, Yukihide Kanemitsu, Takashi Hirai, Yasushi Yatabe, Hideo Tanaka and Kazuo Tajima
    Citation: BMC Cancer 2009 9:379
  37. The malignant potential of serous ovarian tumors, the most common ovarian tumor subtype, varies from benign to low malignant potential (LMP) tumors to frankly invasive cancers. Given the uncertainty about the ...

    Authors: Melissa A Merritt, Peter G Parsons, Tanya R Newton, Adam C Martyn, Penelope M Webb, Adèle C Green, David J Papadimos and Glen M Boyle
    Citation: BMC Cancer 2009 9:378
  38. The glycosylphosphatidylinositol (GPI)-anchored epithelial extracellular membrane serine protease prostasin (PRSS8) is expressed abundantly in normal epithelia and essential for terminal epithelial differentia...

    Authors: Li-Mei Chen, Nicole J Verity and Karl X Chai
    Citation: BMC Cancer 2009 9:377
  39. Colorectal cancer (CRC) is one of the leading causes of malignant death worldwide. Because young age of onset is often considered a poor prognostic factor for CRC, it is important to identify the poor outcomes...

    Authors: Chun-Chao Chang, Shung-Haur Yang, Chih-Cheng Chien, Shu-Hung Chen, Shiann Pan, Chia-Long Lee, Chih-Ming Lin, Hsiao-Lun Sun, Chi-Cheng Huang, Yih-Yiing Wu, Ruey-Neng Yang and Chi-Jung Huang
    Citation: BMC Cancer 2009 9:376
  40. This study is a retrospective evaluation of the efficacy of neoadjuvant chemotherapy (NC) with a vinorelbine (V) and epirubicin (E) intravenous combination regimen and is aimed at identification of predictive ...

    Authors: Ou Huang, CanMing Chen, JiaYi Wu, ShuJie Chen, XiaoSong Chen, GuangYu Liu, Zhen Hu, JingSong Lu, Jiong Wu, ZhiMin Shao, ZhenZhou Shen and KunWei Shen
    Citation: BMC Cancer 2009 9:375
  41. MicroRNAs (MiRNAs) are short non-coding RNAs that control protein expression through various mechanisms. Their altered expression has been shown to be associated with various cancers. The aim of this study was...

    Authors: Greg M Arndt, Lesley Dossey, Lara M Cullen, Angela Lai, Riki Druker, Michael Eisbacher, Chunyan Zhang, Nham Tran, Hongtao Fan, Kathy Retzlaff, Anton Bittner and Mitch Raponi
    Citation: BMC Cancer 2009 9:374
  42. The incidence of oral and pharyngeal (including oral cavity, oropharynx and hypopharynx) carcinoma increases rapidly in Asia and South Pacific because of betel quid chewing. Thus far, large-scale epidemiologic...

    Authors: Kuan-Der Lee, Chang-Hsien Lu, Ping-Tsung Chen, Chunghuang Hubert Chan, Jen-Tsun Lin, Cih-En Huang, Chih-Cheng Chen and Min-Chi Chen
    Citation: BMC Cancer 2009 9:373
  43. Sulfasalazine, a NF-kappaB and x(c)-cystine/glutamate antiport inhibitor, has demonstrated a strong antitumoral potential in preclinical models of malignant gliomas. As it presents an excellent safety profile,...

    Authors: Pierre A Robe, Didier H Martin, Minh T Nguyen-Khac, Maria Artesi, Manuel Deprez, Adelin Albert, Sophie Vanbelle, Stephane Califice, Markus Bredel and Vincent Bours
    Citation: BMC Cancer 2009 9:372
  44. Homeodomain proteins control fundamental cellular processes in development and in cancer if deregulated. Three members of the NK-like subfamily of homeobox genes (NKLs), TLX1, TLX3 and NKX2-5, are implicated i...

    Authors: Stefan Nagel, Letizia Venturini, Grzegorz K Przybylski, Piotr Grabarczyk, Corinna Meyer, Maren Kaufmann, Karin Battmer, Christian A Schmidt, Hans G Drexler, Michaela Scherr and Roderick AF MacLeod
    Citation: BMC Cancer 2009 9:371
  45. Analysis of 23 published transcriptome studies allowed us to identify nine genes displaying frequent alterations in HNSCC (FN1, MMP1, PLAU, SPARC, IL1RN, KRT4, KRT13, MAL, and TGM3). We aimed to independently con...

    Authors: Benjamin Lallemant, Alexandre Evrard, Christophe Combescure, Heliette Chapuis, Guillaume Chambon, Caroline Raynal, Christophe Reynaud, Omar Sabra, Dominique Joubert, Frédéric Hollande, Jean-Gabriel Lallemant, Serge Lumbroso and Jean-Paul Brouillet
    Citation: BMC Cancer 2009 9:370
  46. Carcinoma of the thyroid gland is an uncommon cancer, but the most frequent malignancy of the endocrine system. Most thyroid cancers are derived from the follicular cell. Follicular carcinoma (FTC) is consider...

    Authors: Patricia J McLaughlin, Ian S Zagon, Sunny S Park, Andrea Conway, Renee N Donahue and David Goldenberg
    Citation: BMC Cancer 2009 9:369
  47. Chemotherapy resistance remains a major obstacle in the treatment of women with ovarian cancer. Establishing predictive markers of chemoresponse would help to individualize therapy and improve survival of ovar...

    Authors: Lovisa Österberg, Kristina Levan, Karolina Partheen, Ulla Delle, Björn Olsson, Karin Sundfeldt and György Horvath
    Citation: BMC Cancer 2009 9:368
  48. In Her2-positive advanced breast cancer, the upfront use of trastuzumab is well established. Upon progression on first-line therapy, patients may be switched to lapatinib. Others however remain candidates for ...

    Authors: Rupert Bartsch, Catharina De Vries, Ursula Pluschnig, Peter Dubsky, Zsuzsanna Bago-Horvath, Simon P Gampenrieder, Margaretha Rudas, Robert M Mader, Andrea Rottenfusser, Christoph Wiltschke, Michael Gnant, Christoph C Zielinski and Guenther G Steger
    Citation: BMC Cancer 2009 9:367
  49. Aberrant activity of tyrosine-phosphorylated proteins is commonly associated with HCC metastasis. Cell signaling events driven by these proteins are implicated in numerous processes that alter cancer cell beha...

    Authors: Haiyu Li, Zhenggang Ren, Xiaonan Kang, Lan Zhang, Xuefei Li, Yan Wang, Tongchun Xue, Yuefang Shen and Yinkun Liu
    Citation: BMC Cancer 2009 9:366

Featured videos

View featured videos from across the BMC-series journals