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  1. Brain metastasis is a common outcome in non-small cell lung cancer, and despite aggressive treatment, its clinical outcome is still frustrating. In recent years, immunotherapy has been developing rapidly, howe...

    Authors: Jin-Sheng Liu, Yu-Xiang Cai, Yong-Ze He, Jian Xu, Su-Fang Tian and Zhi-Qiang Li
    Citation: BMC Cancer 2024 24:123
    Content type: Research Published on:

  4. Observational studies have explored the association of psychiatric disorders and the risk of brain cancers. However, the causal effect of specific mental illness on glioma remains elusive due to the lack of so...

    Authors: Wenzhuo Yang, Yu Han, Changjia He, Sheng Zhong, Fei Ren, Zhongping Chen, Yonggao Mou and Ke Sai
    Citation: BMC Cancer 2024 24:118
    Content type: Research Published on:

  5. For brain metastases (BMs) from EGFR/ALK-positive non-small cell lung cancer (NSCLC), the best time to administer tyrosine kinase inhibitors (TKIs) and brain radiotherapy (RT) has not been identified. This analys...

    Authors: Jing Qian, Zelai He, Ying Wu, Hongwei Li, Qun Zhang and Xianming Li
    Citation: BMC Cancer 2024 24:117
    Content type: Research Published on:

  6. Pancreatic adenocarcinoma (PDAC) ranks as the fourth leading cause for cancer-related deaths worldwide. N6-methyladenosine (m6A) and long non-coding RNAs (lncRNAs) are closely related with poor prognosis and i...

    Authors: Xia-Qing Li, Shi-Qi Yin, Lin Chen, Aziguli Tulamaiti, Shu-Yu Xiao, Xue-Li Zhang, Lei Shi, Xiao-Cao Miao, Yan Yang and Xin Xing
    Citation: BMC Cancer 2024 24:116
    Content type: Research Published on:

  7. Selective lateral pelvic lymph node (LPN) dissection (LPND) following neoadjuvant chemoradiotherapy (nCRT) for rectal cancer is widely recognized. This study aimed to determine the effects of nCRT before LPND ...

    Authors: Zhongshi Xie, Qichen Chen, Bo Feng, Yujuan Jiang, Xin Wang, Wei Xing and Qian Liu
    Citation: BMC Cancer 2024 24:115
    Content type: Research Published on:

  8. Authors: Elif Şenocak Taşçı, Başak Oyan, Özlem Sönmez, Arda Ulaş Mutlu, Muhammed Mustafa Atcı, Abdullah Sakin, İrem Öner, Havva Yeşil Çınkır, Melek Karakurt Eryılmaz, Dilek Çağlayan, Onur Yazdan Balçık, Nail Paksoy, Senem Karabulut, Derya Kıvrak Salim, Cemil Bilir, Miraç Özen…
    Citation: BMC Cancer 2024 24:114
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:16

  9. Extracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its supporting role in lymph node metastases is under continuous investigatio...

    Authors: Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong, Binbin Shuai, Yingkun Luo, Tingting Guo, Wentao Huang and Shenyingjie Zhang
    Citation: BMC Cancer 2024 24:113
    Content type: Research Published on:

  10. Since the Z0011 trial, the assessment of axillary lymph node status has been redirected from the previous assessment of the occurrence of lymph node metastasis alone to the assessment of the degree of lymph no...

    Authors: Hua Shao, Yixin Sun, Ziyue Na, Hui Jing, Bo Li, Qiucheng Wang, Cui Zhang and Wen Cheng
    Citation: BMC Cancer 2024 24:112
    Content type: Research Published on:

  11. Myelodysplastic syndrome (MDS) is known to arise through the pathogenic bone marrow mesenchymal stem cells (MSC) by interacting with hematopoietic stem cells (HSC). However, due to the strong heterogeneity of ...

    Authors: Chunlai Yin, Yanqi Li, Cheng Zhang, Shizhu Zang, Zilong Wang, Xue Yan, Tonghui Ma, Xia Li and Weiping Li
    Citation: BMC Cancer 2024 24:111
    Content type: Research Published on:

  12. Lymphoplasmacyte-rich meningioma(LPM) is a rare subtype of meningioma with a low degree of malignancy and an overall preferable prognosis. The purpose of this article is to increase the understanding of the di...

    Authors: Xiaoxi Zhu, Yanhua Liu, Weiwei Guo, Qi Liang, Chengliang Pan, Bin Tan and Ying Yu
    Citation: BMC Cancer 2024 24:110
    Content type: Research Published on:

  13. There is an aberrant expression of NBAT-1 in various human cancers, which was proven to limit the proliferation, invasion, and metastasis of tumour cells via multiple approaches. Most existing research focuses...

    Authors: Yang Yu, Kedi Fan, Tingting Ni, Xun Lei Zhang, Xiaoqin Su and Lei Yang
    Citation: BMC Cancer 2024 24:109
    Content type: Research Published on:

  14. In neuro-oncology, the inclusion of tumor patients in the molecular tumor board has only become increasingly widespread in recent years, but so far there are no standards for indication, procedure, evaluation,...

    Authors: Lisa S. Hönikl, Sebastian Lange, Vicki M. Butenschoen, Claire Delbridge, Bernhard Meyer, Stephanie E. Combs, Anna Lena Illert and Friederike Schmidt-Graf
    Citation: BMC Cancer 2024 24:108
    Content type: Research Published on:

  15. Paclitaxel liposome (Lipusu) is known to be effective in non-small cell lung cancer (NSCLC) as first-line treatment. This study aimed to evaluate the effectiveness and safety of paclitaxel liposome based chemo...

    Authors: Ran Li, Hongge Liang, Jun Li, Zhenyu Shao, Donghong Yang, Jing Bao, Keqiang Wang, Wen Xi, Zhancheng Gao, Renhua Guo and Xinlin Mu
    Citation: BMC Cancer 2024 24:107
    Content type: Research Published on:

  17. Colibactin, a genotoxin produced by polyketide synthase harboring (pks+) bacteria, induces double-strand breaks and chromosome aberrations. Consequently, enrichment of pks+Escherichia coli in colorectal cancer an...

    Authors: Diantha Terlouw, Arnoud Boot, Quinten R. Ducarmon, Sam Nooij, Manon Suerink, Monique E. van Leerdam, Demi van Egmond, Carli M. Tops, Romy D. Zwittink, Dina Ruano, Alexandra M. J. Langers, Maartje Nielsen, Tom van Wezel and Hans Morreau
    Citation: BMC Cancer 2024 24:104
    Content type: Research Published on:

  18. Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a specific protein is a foundation of precision medicine and treatment. High expression of the pr...

    Authors: Karunakar Saamarthy, Kristofer Ahlqvist, Renée Daams, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis, Julhash U. Kazi, Wondossen Sime and Ramin Massoumi
    Citation: BMC Cancer 2024 24:103
    Content type: Research Published on:

  19. Recent studies have demonstrated that accelerated enhanced recovery after colorectal surgery is feasible for specific patient populations. The accelerated enhanced recovery protocols (ERP) tend to vary, and th...

    Authors: Misha A. T. Sier, Anke H. C. Gielen, Thaís T. T. Tweed, Noémi C. van Nie, Tim Lubbers and Jan H. M. B. Stoot
    Citation: BMC Cancer 2024 24:102
    Content type: Research Published on:

  20. Vulvar and vaginal melanoma (VuM & VaM) is a rare gynecologic malignancy with high mortality but low effectiveness to checkpoint immunotherapy compared to cutaneous melanoma. This article aims to elucidate the...

    Authors: Xinqi Wang, Jiahui Li, Yifei Li, Mingyi Lv, Xue Dong, Zhenxin Fan and Tao Guo
    Citation: BMC Cancer 2024 24:101
    Content type: Research Published on:

  21. Immunotherapy targeting PD-1/PD-L1 has revolutionized the treatment of extensive-stage small cell lung cancer (ES-SCLC). However, clinical trials suggest differential efficacy of anti-PD-1 agents and anti-PD-L...

    Authors: Boyu Qin, Lingli Xin, Chen Liang, Lingling Li, Qi Song, Yaping Long, Xiaoling Zhang, Dan Wang, Weiwei Shi, Jing Zhang, Yi Hu, Bo Yang and Qi Xiong
    Citation: BMC Cancer 2024 24:100
    Content type: Research Published on:

  22. Pure uterine serous carcinoma (p-USC) and mixed tumors with serous component (m-USC) are aggressive subtypes of endometrial cancer associated with high mortality rates. This retrospective study aimed to compar...

    Authors: Xuewu You, Yangyang Dong, Jiaqi Wang, Yuan Cheng, Yuanyuan Jia, Xiaobo Zhang and Jianliu Wang
    Citation: BMC Cancer 2024 24:99
    Content type: Research Published on:

  24. The outcomes of immune checkpoint blockade for colorectal cancer (CRC) treatment are unsatisfactory. Furthermore, the efficacy of immune checkpoint blockade for liver metastasis of various cancer is poor. Here...

    Authors: Chie Takasu, Yuji Morine, Kozo Yoshikawa, Toshihiro Nakao, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Yuma Wada, Toshiaki Yoshimoto and Mitsuo Shimada
    Citation: BMC Cancer 2024 24:97
    Content type: Research Published on:

  25. Breast cancer rates and the number of breast cancer survivors have been increasing among women in Iran. Effective responses from healthcare depend on appropriately identifying survivors’ needs. This study inve...

    Authors: Rahimeh Khajoei, Payam Azadeh, Sima ZohariAnboohi, Mahnaz Ilkhani and Fatemah Heshmati Nabavi
    Citation: BMC Cancer 2024 24:96
    Content type: Research Published on:

  26. Sarcopenia has received increasing attention in non-small cell lung cancer (NSCLC). Red blood cell distribution width (RDW) is a significant component of the complete blood count and indicates the heterogeneit...

    Authors: Qing-chun Jia, Ling Qin, Ye Niu, Le Liu, Ping-ping Liu, Shi-di Miao, Ming-ming Cui and Rui-tao Wang
    Citation: BMC Cancer 2024 24:95
    Content type: Research Published on:

  27. Mitochondria, which serve as the fundamental organelle for cellular energy and metabolism, are closely linked to the growth and survival of cancer cells. This study aims to identify and assess Sideroflexin1 (S...

    Authors: Wenting Liu, Qingwu Du, Ting Mei, Jingya Wang, Dingzhi Huang and Tingting Qin
    Citation: BMC Cancer 2024 24:94
    Content type: Research Published on:

  28. Several publications suggest that UTP11 may be a promising gene engaged for involvement of hepatocellular carcinoma (HCC) pathology. However, there are extremely limited biological, mechanistic and clinical st...

    Authors: Yan Chen, Xiaowei Zhang, Mingcheng Zhang, Wenting Fan, Yueyue Lin and Guodong Li
    Citation: BMC Cancer 2024 24:93
    Content type: Research Published on:

  29. The efficacy and safety of subxiphoid thoracoscopic thymectomy (SVATS) for early thymoma are unknown. The purposes of this meta-analysis were to evaluate the effectiveness and safety of SVATS for early thymoma...

    Authors: Jincheng Wang, Ti Tong, Kun Zhang, Haiping Guo, Yang Liu, Jindong Li, Haiyang Zhang, Quanqing Li, Zhenxiao Zhang and Yinghao Zhao
    Citation: BMC Cancer 2024 24:92
    Content type: Research Published on:

  30. The current standard of care in the neoadjuvant setting for high-risk HER2-positive (HER2 +) breast cancer is to combine systemic chemotherapy with dual HER2 blockade, trastuzumab and pertuzumab. Targeted ther...

    Authors: Gavin P. Dowling, Sinead Toomey, Philip Bredin, Imelda Parker, Eibhlin Mulroe, Jacinta Marron, Olivia McLoughlin, Ausra Teiserskiene, Colm Power, Anne Marie O’Shea, Megan Greally, Patrick G. Morris, Deirdre Duke, Arnold D. K. Hill and Bryan T. Hennessy
    Citation: BMC Cancer 2024 24:91
    Content type: Study Protocol Published on:

  31. CRC with liver metastases is a major contributor to cancer-related mortality. Despite advancements in liver resection techniques, patient survival remains a concern due to high recurrence rates. This study see...

    Authors: Mathieu Pecqueux, Frederik Brückner, Florian Oehme, Sebastian Hempel, Franziska Baenke, Carina Riediger, Marius Distler, Jürgen Weitz and Christoph Kahlert
    Citation: BMC Cancer 2024 24:90
    Content type: Research Published on:

  32. Glioblastoma (GBM) is the most aggressive malignant central nervous system tumor with a poor prognosis.The malignant transformation of glioma cells via epithelial-mesenchymal transition (EMT) has been observed...

    Authors: Li Li, Siyu Xia, Zitong Zhao, Lili Deng, Hanbing Wang, Dongbo Yang, Yizhou Hu, Jingjing Ji, Dayong Huang and Tao Xin
    Citation: BMC Cancer 2024 24:89
    Content type: Research Published on:

  33. Recently, with the advancement of medical technology, the postoperative morbidity of pelvic exenteration (PE) has gradually decreased, and it has become a curative treatment option for some patients with recur...

    Authors: Jie-Hai Yu, Chong-Jie Tong, Qi-Dan Huang, Yun-Lin Ye, Gong Chen, Hao Li, Yong-Shan Wen, Fan Yang, Nan-Bin Luo, Guang-Yu Xu and Ying Xiong
    Citation: BMC Cancer 2024 24:88
    Content type: Research Published on:

  34. Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, and its molecular mechanisms are unclear. Nucleolar and spindle-associated protein 1 (NUSAP1), an indispensable mitotic regulator, has been reporte...

    Authors: Yuan Liu, Rong Tang, Qing-Cai Meng, Si Shi, Jin Xu, Xian-Jun Yu, Bo Zhang and Wei Wang
    Citation: BMC Cancer 2024 24:87
    Content type: Research Published on:

  35. Surgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However, SLNB may be associated with postoperative arm morbidities. For most pat...

    Authors: Ida Skarping, Julia Ellbrant, Looket Dihge, Mattias Ohlsson, Linnea Huss, Pär-Ola Bendahl and Lisa Rydén
    Citation: BMC Cancer 2024 24:86
    Content type: Research Published on:

  36. The aim of this study was to investigate genetic alterations within breast cancer in the setting of recurrent or de novo stage IV disease.

    Authors: Mirai Ido, Kimihito Fujii, Hideyuki Mishima, Akihito Kubo, Masayuki Saito, Hirona Banno, Yukie Ito, Manami Goto, Takahito Ando, Yukako Mouri, Junko Kousaka, Tsuneo Imai and Shogo Nakano
    Citation: BMC Cancer 2024 24:85
    Content type: Research Published on:

  37. Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–40 years, with increasing incidence worldwide. About 33 ~ 50% of the patients present with metastatic disease at diagnosis. TG...

    Authors: Hwayoung Noh, Amélie Anota, Rodolf Mongondry, Renaud Meyrand, Carmen Dupuis, Camille Schiffler, Philippe Marijnen, Sabina Rinaldi, Joel Lachuer, Pekka Keski-Rahkonen, Marc J Gunter, Aude Fléchon, Béatrice Fervers and Olivia Pérol
    Citation: BMC Cancer 2024 24:84
    Content type: Study Protocol Published on:

  38. Glioblastoma (GBM) is the most common adult malignant brain tumour, with an incidence of 5 per 100,000 per year in England. Patients with tumours showing O6-methylguanine-DNA methyltransferase (MGMT) promoter met...

    Authors: Divyalakshmi Bhaskaran, Joshua Savage, Amit Patel, Fiona Collinson, Rhys Mant, Florien Boele, Lucy Brazil, Sara Meade, Peter Buckle, Siân Lax, Lucinda Billingham and Susan C. Short
    Citation: BMC Cancer 2024 24:83
    Content type: Study Protocol Published on:

  39. Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epi...

    Authors: Maximilian Mastall, Patrick Roth, Andrea Bink, Angela Fischer Maranta, Heinz Läubli, Andreas Felix Hottinger, Thomas Hundsberger, Denis Migliorini, Adrian Ochsenbein, Katharina Seystahl, Lukas Imbach, Tibor Hortobagyi, Leonhard Held, Michael Weller and Hans-Georg Wirsching
    Citation: BMC Cancer 2024 24:82
    Content type: Study Protocol Published on:

  40. Breast cancer is the most common cancer in terms of incidence and mortality among women worldwide, including in Africa, and a rapid increase in the number of new cases of breast cancer has recently been observ...

    Authors: Clémence Schantz, Abdourahmane Coulibaly, Alassane Traoré, Bakary Abou Traoré, Kadiatou Faye, Julie Robin, Luis Teixeira and Valéry Ridde
    Citation: BMC Cancer 2024 24:81
    Content type: Research Published on:

  41. For chronic pain after thoracic surgery, optimal timing of its diagnosis and effective treatment remains unresolved, although several treatment options are currently available. We examined the efficacy and saf...

    Authors: Takuro Miyazaki, Keitaro Matsumoto, Toshihiko Sato, Isao Sano, Katsuro Furukawa, Koichiro Shimoyama, Ryotaro Kamohara, Makoto Suzuki, Masamichi Kondou, Norihiko Ikeda, Shunsuke Tabata, Kazuhito Shiosakai and Takeshi Nagayasu
    Citation: BMC Cancer 2024 24:80
    Content type: Research Published on:

  42. GEFT is a key regulator of tumorigenesis in rhabdomyosarcoma (RMS), and overexpression of GEFT is significantly correlated with distant metastasis, lymph node metastasis, and a poor prognosis, yet the underlyi...

    Authors: Lian Meng, Hao Shang, Qianqian Liu, Zhenzhen Li, Xiaomeng Wang, Qianru Li, Feng Li, Zhenguo Zhao and Chunxia Liu
    Citation: BMC Cancer 2024 24:79
    Content type: Research Published on:

  43. Chemoradiotherapy is a critical treatment for patients with locally advanced and unresectable non-small cell lung cancer (NSCLC), and it is essential to identify high-risk patients as early as possible owing t...

    Authors: Jiaran Li, Li Li, Shanshan Tang, Qingxi Yu, Wenju Liu, Ning Liu, Fengchang Yang, Dexian Zhang and Shuanghu Yuan
    Citation: BMC Cancer 2024 24:78
    Content type: Research Published on:

  44. KRAS is the undisputed champion of oncogenes, and despite its prominent role in oncogenesis as mutated gene, KRAS mutation appears infrequent in gliomas. Nevertheless, gliomas are considered KRAS-driven cancers d...

    Authors: Candida Zuchegna, Stefano Leone, Antonella Romano, Antonio Porcellini and Samantha Messina
    Citation: BMC Cancer 2024 24:77
    Content type: Research Published on:

  45. Total laryngectomy (TL) is a surgical procedure commonly performed on patients with advanced laryngeal or hypopharyngeal carcinoma. One of the most common postoperative complications following TL is the develo...

    Authors: Maartje A. van Beers, Caroline M. Speksnijder, Carla H. van Gils, Geert W.J. Frederix, Jan Willem Dankbaar and Remco de Bree
    Citation: BMC Cancer 2024 24:76
    Content type: Study Protocol Published on:

  46. Obesity-induced abnormal bone marrow microenvironment is one of the important risk element for bone metastasis in prostate cancer (PCa). The present study aimed to determine whether obesity-induced elevation i...

    Authors: Jingzhou Wang, Jie Liu, Chenggang Yuan, Bingqi Yang, Huai Pang, Keru Chen, Jiale Feng, Yuchun Deng, Xueting Zhang, Wei Li, Cuizhe Wang, Jianxin Xie and Jun Zhang
    Citation: BMC Cancer 2024 24:75
    Content type: Research Published on:

  47. Poor oral health has been linked to various systemic diseases, including multiple cancer types, but studies of its association with lung cancer have been inconclusive.

    Authors: Yukiko Yano, Christian C. Abnet, Gholamreza Roshandel, Akua Graf, Hossein Poustchi, Masoud Khoshnia, Akram Pourshams, Farin Kamangar, Paolo Boffetta, Paul Brennan, Sanford M. Dawsey, Emily Vogtmann, Reza Malekzadeh and Arash Etemadi
    Citation: BMC Cancer 2024 24:74
    Content type: Research Published on:

  48. Several studies have proved that Polygenic Risk Score (PRS) is a potential candidate for realizing precision screening. The effectiveness of low-dose computed tomography (LDCT) screening for lung cancer has be...

    Authors: Zixuan Zhao, Shuyan Gu, Yi Yang, Weijia Wu, Lingbin Du, Gaoling Wang and Hengjin Dong
    Citation: BMC Cancer 2024 24:73
    Content type: Research Published on:

  49. Radiotherapy (RT) is an effective and available local treatment for patients with refractory or relapsed (R/R) aggressive B-cell lymphomas. However, the value of hypofractionated RT in this setting has not bee...

    Authors: Cheng Huang, Tian-Lan Tang, Yan-Yan Qiu, Yu-Ping Lin, Si-Lin Chen, Rui-Zhi Zhao, Gui-Qing Shi, Si-Qin Liao, Jin-Hua Chen, Hai-Ying Fu, Jian-Zhi Liu, Ben-Hua Xu, Ting-Bo Liu and Yong Yang
    Citation: BMC Cancer 2024 24:72
    Content type: Research Published on:

  50. The single-visit strategy, also known as the “screen-and-treat” approach, is widely used to screen for cervical cancer in low- and middle-income countries. The screen-and-treat approach leads to unnecessary or...

    Authors: Godfrey K. Kaizilege, Edgar Ndaboine, Clotilda Chuma, Fridolin Mujuni, Richard Kiritta, Dismas Matovelo, Oscar Ottoman, Edrick Elias, Nestory Masalu, Benson R. Kidenya and Humphrey D. Mazigo
    Citation: BMC Cancer 2024 24:66
    Content type: Research Published on:

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