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Articles

906 result(s) within Volume 17 of BMC Cancer

Page 7 of 19

  1. Due to the presence of both classical estrogen receptor (ERα) and another ER subtype (ERβ) in ovarian cancer, hormonal treatment is an attractive option. However, response to tamoxifen in ovarian cancer is mod...

    Authors: Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Yan Wang, Thomas H. Y. Leung, Stephanie S. Liu, Annie N. Y. Cheung and Hextan Y. S. Ngan
    Citation: BMC Cancer 2017 17:606
    Content type: Research article Published on:

  2. N-acetyltransferase 10 (NAT10) is a histone acetyltransferase which is involved in a wide range of cellular processes. Recent evidences indicate that NAT10 is involved in the development of human cancers. Prev...

    Authors: Qijiong Li, Xiaofeng Liu, Kemin Jin, Min Lu, Chunfeng Zhang, Xiaojuan Du and Baocai Xing
    Citation: BMC Cancer 2017 17:605
    Content type: Research article Published on:

  3. The recently developed reagent, eribulin mesylate (eribulin), is a microtubule dynamics inhibitor with a mechanism of action that differs from those of taxanes and vinca alkaloids. This drug is considered to b...

    Authors: Shinichiro Kashiwagi, Wakaba Fukushima, Yuka Asano, Wataru Goto, Koji Takada, Satoru Noda, Tsutomu Takashima, Naoyoshi Onoda, Masahiko Ohsawa, Kosei Hirakawa and Masaichi Ohira
    Citation: BMC Cancer 2017 17:604
    Content type: Research article Published on:

  4. Large gap exists between clinical practice and recommended care and large room exists for the improvement of care quality for non-small cell lung cancer (NSCLC) in China. Results of some studies have shown tha...

    Authors: Xinyu Wang, Shaofei Su, Shouyi Li, Han Bao, Meiqi Zhang, Dan Liu, Hao Jiang, Jiaying Wang and Meina Liu
    Citation: BMC Cancer 2017 17:603
    Content type: Research article Published on:

  5. Describe a single-center real-world experience with comprehensive genomic profiling (CGP) to identify genotype directed therapy (GDT) options for patients with malignancies refractory to standard treatment opt...

    Authors: Talal Hilal, Mary Nakazawa, Jacob Hodskins, John L. Villano, Aju Mathew, Guarav Goel, Lars Wagner, Susanne M. Arnold, Philip DeSimone, Lowell B. Anthony and Peter J. Hosein
    Citation: BMC Cancer 2017 17:602
    Content type: Research article Published on:

  6. Long Interspersed Nuclear Elements-1 (LINEs-1) methylation from white blood cells (WBCs) DNA has been proposed as biomarker associated with different types of cancer. The aim of the present study was to invest...

    Authors: Martina Barchitta, Annalisa Quattrocchi, Andrea Maugeri, Carolina Canto, Nadia La Rosa, Maria Antonietta Cantarella, Giuseppa Spampinato, Aurora Scalisi and Antonella Agodi
    Citation: BMC Cancer 2017 17:601
    Content type: Research article Published on:

  7. Lung cancer survivors are more likely to develop colorectal and stomach cancer than the general population. However, little is known about the current status of gastrointestinal cancer screening practices and ...

    Authors: Sang Min Park, Jongmog Lee, Young Ae Kim, Yoon Jung Chang, Moon Soo Kim, Young Mog Shim, Jae Ill Zo and Young Ho Yun
    Citation: BMC Cancer 2017 17:600
    Content type: Research article Published on:

  8. Cancer survivorship is of increasing importance in post-treatment care. Sexual health (SH) and femininity can be crucial issues for women surviving cancer. We aimed to determine a more complete understanding o...

    Authors: Anne Oberguggenberger, Caroline Martini, Nathalie Huber, Lesley Fallowfield, Michael Hubalek, Martin Daniaux, Barbara Sperner-Unterweger, Bernhard Holzner, Monika Sztankay, Eva Gamper and Verena Meraner
    Citation: BMC Cancer 2017 17:599
    Content type: Research article Published on:

  9. Treatment of tonsil cancer, a subset of oropahryngeal cancer, varies between surgery and radiotherapy. Well-designed studies in tonsil cancer have been rare and it is still controversial which treatment is opt...

    Authors: Sanghyuk Song, Hong-Gyun Wu, Chang Geol Lee, Ki Chang Keum, Mi Sun Kim, Yong Chan Ahn, Dongryul Oh, Hyo Jung Park, Sang-Wook Lee, Geumju Park, Sung Ho Moon, Kwan Ho Cho, Yeon-Sil Kim, Yongkyun Won, Young-Taek Oh, Won-Taek Kim…
    Citation: BMC Cancer 2017 17:598
    Content type: Research article Published on:

  10. Racial disparities in the incidence of major cancers may be attributed to differences in the prevalence of established, modifiable risk factors such as obesity, smoking, physical activity and diet.

    Authors: Tomi Akinyemiju, Howard Wiener and Maria Pisu
    Citation: BMC Cancer 2017 17:597
    Content type: Research article Published on:

  11. Lung cancer (LC) is the leading cause of cancer deaths in men and the second most frequent cause of cancer deaths in women in Estonia. The study aimed to analyze time trends in LC incidence and mortality in Es...

    Authors: Tiiu Aareleid, Mari-Liis Zimmermann, Aleksei Baburin and Kaire Innos
    Citation: BMC Cancer 2017 17:596
    Content type: Research article Published on:

  12. Central venous access device (CVAD) associated complications are a preventable source of patient harm, frequently resulting in morbidity and delays to vital treatment. Dressing and securement products are used...

    Authors: Amanda J. Ullman, Tricia Kleidon, Victoria Gibson, Craig A. McBride, Gabor Mihala, Marie Cooke and Claire M. Rickard
    Citation: BMC Cancer 2017 17:595
    Content type: Research article Published on:

  13. Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies. Herein, we investigated the efficacy of an emerging oncolytic, Maraba...

    Authors: Jessica G. Tong, Yudith Ramos Valdes, Milani Sivapragasam, John W. Barrett, John C. Bell, David Stojdl, Gabriel E. DiMattia and Trevor G. Shepherd
    Citation: BMC Cancer 2017 17:594
    Content type: Research article Published on:

  15. The EGFR and downstream signaling pathways play an important role in tumorigenesis in oral squamous cell carcinoma (OSCC). Gene copy number alteration is one mechanism for overexpressing the EGFR protein and w...

    Authors: Shiang-Fu Huang, Huei-Tzu Chien, Sou-De Cheng, Wen-Yu Chuang, Chun-Ta Liao and Hung-Ming Wang
    Citation: BMC Cancer 2017 17:592
    Content type: Research article Published on:

  17. Neuron-Specific enolase (NSE) has been used as a typical tumor marker and shows a potential to diagnose malignant pleural effusion (MPE). The ability of NSE in diagnosing MPE has been investigated in many stud...

    Authors: Jing Zhu, Mei Feng, Liqun Liang, Ni Zeng, Chun Wan, Ting Yang, Yongchun Shen and Fuqiang Wen
    Citation: BMC Cancer 2017 17:590
    Content type: Research article Published on:

  18. Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study i...

    Authors: Yuji Yamashita, Shin Nishiumi, Seishi Kono, Shintaro Takao, Takeshi Azuma and Masaru Yoshida
    Citation: BMC Cancer 2017 17:589
    Content type: Research article Published on:

  19. DNA methylation changes occurring in cancer cells are featured with both promoter CpG island hypermethylation and diffuse genomic hypomethylation. Long interspersed element-1 (LINE-1) is repeated in an intersp...

    Authors: Seorin Jeong, Kyoungbun Lee, Xianyu Wen, Younghoon Kim, Nam-Yun Cho, Ja-June Jang and Gyeong Hoon Kang
    Citation: BMC Cancer 2017 17:588
    Content type: Research article Published on:

  20. Cancer is one of the major health problems worldwide. In this article, we present for the first time the cancer incidence trends, the distribution and the socioeconomic profile of incident cancer cases in East...

    Authors: Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, Meryem Ouarzane, Redouane Boulouiz and Mohammed Bellaoui
    Citation: BMC Cancer 2017 17:587
    Content type: Research article Published on:

  21. The FOLFOX regimen, i.e., folinic acid (FOL), fluorouracil (F) and oxaliplatin (OX), is a drug cocktail that is used to treat gastric and colorectal cancers. Despite the concomitant improvements in response ra...

    Authors: Annick De Weerdt, Amélie Dendooven, Annemie Snoeckx, Jan Pen, Martin Lammens and Philippe G. Jorens
    Citation: BMC Cancer 2017 17:586
    Content type: Case report Published on:

  22. Venous thromboembolic events (VTE) are common in cancer patients and associated with higher mortality. In vivo thrombosis and anticoagulation might be involved in tumor growth and progression. We studied the a...

    Authors: Pete T. T. Kinnunen, Teemu J. Murtola, Kirsi Talala, Kimmo Taari, Teuvo L. J. Tammela and Anssi Auvinen
    Citation: BMC Cancer 2017 17:585
    Content type: Research article Published on:

  23. The variable prognosis in stage III cutaneous melanoma is partially due to unknown prognostic factors. Improved prognostic tools are required to define patients with an increased risk of developing metastatic ...

    Authors: Johan Falkenius, Hemming Johansson, Rainer Tuominen, Marianne Frostvik Stolt, Johan Hansson and Suzanne Egyhazi Brage
    Citation: BMC Cancer 2017 17:584
    Content type: Research article Published on:

  24. Epithelial-mesenchymal transition (EMT), principally involving an E-cadherin to N-cadherin shift, linked to tumor invasion or metastasis, and therapeutic resistance in various human cancer. A growing body of r...

    Authors: Myung-Giun Noh, Se-Jeong Oh, Eun-Jung Ahn, Yeong-Jin Kim, Tae-Young Jung, Shin Jung, Kyung-Keun Kim, Jae-Hyuk Lee, Kyung-Hwa Lee and Kyung-Sub Moon
    Citation: BMC Cancer 2017 17:583
    Content type: Research article Published on:

  25. Using propensity score matching method (PSM) to evaluate the feasibility and clinical outcomes of simultaneous modulated accelerated radiation therapy (SMART) using helical tomotherapy (HT) in patients with na...

    Authors: Lei Du, Xin-Xin Zhang, Lin-Chun Feng, Bao-Lin Qu, Jing Chen, Jun Yang, Hai-Xia Liu, Shou-Ping Xu, Chuan-Bin Xie and Lin Ma
    Citation: BMC Cancer 2017 17:582
    Content type: Research article Published on:

  26. We conducted a multicenter randomized study of adjuvant S-1 administration schedules for surgically treated pathological stage IB-IIIA non-small cell lung cancer patients.

    Authors: Yoshinobu Hata, Takaharu Kiribayashi, Kazuma Kishi, Makoto Nagashima, Takefumi Nakayama, Shingo Ikeda, Mitsutaka Kadokura, Yuichi Ozeki, Hajime Otsuka, Yoshitaka Murakami, Keigo Takagi and Akira Iyoda
    Citation: BMC Cancer 2017 17:581
    Content type: Research article Published on:

  27. The Cancer Genome Atlas Research Network reported that high-grade serous carcinoma (HGSC) can be classified based on gene expression profiles into four subtypes, termed “immunoreactive,” “differentiated,” “pro...

    Authors: Takuma Ohsuga, Ken Yamaguchi, Aki Kido, Ryusuke Murakami, Kaoru Abiko, Junzo Hamanishi, Eiji Kondoh, Tsukasa Baba, Ikuo Konishi and Noriomi Matsumura
    Citation: BMC Cancer 2017 17:580
    Content type: Research article Published on:

  28. Neurofibromatosis type 1 is a relatively common inherited disorder. Patients with neurofibromatosis type 1 are at high risk of developing neurogenic, neuroendocrine and mesenchymal intra-abdominal tumors. Alth...

    Authors: Nihed Abdessayed, Rahul Gupta, Sarra Mestiri, Ahlem Bdioui, Mounir Trimech and Moncef Mokni
    Citation: BMC Cancer 2017 17:579
    Content type: Case report Published on:

  29. The effect of endocrine therapy with tamoxifen (TMX) on weight gain has been reported in the literature, but the outcomes are still controversial. Moreover, previous treatment options, such as chemotherapy (CT...

    Authors: Mariana Tavares Miranda Lima, Kamila Pires de Carvalho, Fernanda Silva Mazzutti, Marcelo de Almeida Maia, Paula Philbert Lajolo Canto, Carlos Eduardo Paiva and Yara Cristina de Paiva Maia
    Citation: BMC Cancer 2017 17:578
    Content type: Research article Published on:

  30. The Basque Colorectal Cancer Screening Programme has both high participation rate and high compliance rate of colonoscopy after a positive faecal occult blood test (FIT). Although, colorectal cancer (CRC) scre...

    Authors: Eunate Arana-Arri, Isabel Idigoras, Begoña Uranga, Raquel Pérez, Ana Irurzun, Iñaki Gutiérrez-Ibarluzea, Callum G. Fraser and Isabel Portillo
    Citation: BMC Cancer 2017 17:577
    Content type: Research article Published on:

  31. Metastatic pancreatic cancer has a dismal prognosis, with a mean six-month progression-free survival of approximately 50% and a median survival of about 11 months. Despite intensive research, only slight impro...

    Authors: Jacek Hajda, Monika Lehmann, Ottheinz Krebs, Meinhard Kieser, Karsten Geletneky, Dirk Jäger, Michael Dahm, Bernard Huber, Tilman Schöning, Oliver Sedlaczek, Albrecht Stenzinger, Niels Halama, Volker Daniel, Barbara Leuchs, Assia Angelova, Jean Rommelaere…
    Citation: BMC Cancer 2017 17:576
    Content type: Study protocol Published on:

  32. Racial disparities exist in the care provided to advanced cancer patients. This article describes an investigation designed to advance the science of healthcare disparities by isolating the effects of patient ...

    Authors: Cezanne M. Elias, Cleveland G. Shields, Jennifer J. Griggs, Kevin Fiscella, Sharon L. Christ, Joseph Colbert, Stephen G. Henry, Beth G. Hoh, Haslyn E. R. Hunte, Mary Marshall, Supriya Gupta Mohile, Sandy Plumb, Mohamedtaki A. Tejani, Alison Venuti and Ronald M. Epstein
    Citation: BMC Cancer 2017 17:575
    Content type: Study protocol Published on:

  33. The squamous cell carcinoma of the anus (SCCA) is a rare disease, but its incidence is markedly increasing. About 15% of patients are diagnosed at metastatic stage, and more than 20% with a localized disease t...

    Authors: Stefano Kim, Marine Jary, Thierry André, Véronique Vendrely, Bruno Buecher, Eric François, François-Clément Bidard, Sarah Dumont, Emmanuelle Samalin, Didier Peiffert, Simon Pernot, Nabil Baba-Hamed, Farid El Hajbi, Olivier Bouché, Jérôme Desrame, Aurélie Parzy…
    Citation: BMC Cancer 2017 17:574
    Content type: Study protocol Published on:

  34. To compare the PSA value at the last follow-up of patients who underwent prostate low-dose rate brachytherapy (LDR-BT) with that of patients who underwent intensity-modulated radiation therapy (IMRT).

    Authors: Nobumichi Tanaka, Isao Asakawa, Yasushi Nakai, Makito Miyake, Satoshi Anai, Tomomi Fujii, Masatoshi Hasegawa, Noboru Konishi and Kiyohide Fujimoto
    Citation: BMC Cancer 2017 17:573
    Content type: Research article Published on:

  35. Tumor-specific biomarkers are a prerequisite for the development of targeted imaging and therapy in oral squamous cell carcinoma (OSCC). urokinase-type Plasminogen Activator Receptor (uPAR), Tissue Factor (TF)...

    Authors: Anders Christensen, Katalin Kiss, Giedrius Lelkaitis, Karina Juhl, Morten Persson, Birgitte Wittenborg Charabi, Jann Mortensen, Julie Lyng Forman, Anne Lyngholm Sørensen, David Hebbelstrup Jensen, Andreas Kjaer and Christian von Buchwald
    Citation: BMC Cancer 2017 17:572
    Content type: Research article Published on:

  36. Elderly patient with advanced cancer is one of the most vulnerable populations. Skeletal muscle depletion during chemotherapy may have substantial impact on their physical function. However, there is little in...

    Authors: Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori…
    Citation: BMC Cancer 2017 17:571
    Content type: Research article Published on:

  39. Studies have indicated a pervasive pattern of decreasing healthcare costs during elderly patients’ last year of life. The aim of this study was to explore the predictors of high healthcare costs (HC) in elderl...

    Authors: Jui-Kun Chiang and Yee-Hsin Kao
    Citation: BMC Cancer 2017 17:568
    Content type: Research article Published on:

  40. This study aimed to evaluate the long-term outcome and toxicities in patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated by concurrent chemoradiotherapy (CCRT) with/without adding cetu...

    Authors: Yang Li, Qiu-Yan Chen, Lin-Quan Tang, Li-Ting Liu, Shan-Shan Guo, Ling Guo, Hao-Yuan Mo, Ming-Yuan Chen, Xiang Guo, Ka-Jia Cao, Chao-Nan Qian, Mu-Shen Zeng, Jin-Xin Bei, Jian-Yong Shao, Ying Sun, Jing Tan…
    Citation: BMC Cancer 2017 17:567
    Content type: Research article Published on:

  42. Maintenance therapy (MT) with pemetrexed has been shown to improve overall and progression-free survival of patients with non-squamous non-small cell lung cancer (NSCLC), without impairing patients’ health-rel...

    Authors: Monika Sztankay, Johannes Maria Giesinger, August Zabernigg, Elisabeth Krempler, Georg Pall, Wolfgang Hilbe, Otto Burghuber, Maximilian Hochmair, Gerhard Rumpold, Stephan Doering and Bernhard Holzner
    Citation: BMC Cancer 2017 17:565
    Content type: Research article Published on:

  43. The aim of this study was to assess the feasibility and potential benefit of a brief psychosocial intervention based on cognitive-behavioral therapy performed in addition to early palliative care (PC) in the r...

    Authors: Thamires Monteiro do Carmo, Bianca Sakamoto Ribeiro Paiva, Cleyton Zanardo de Oliveira, Maria Salete de Angelis Nascimento and Carlos Eduardo Paiva
    Citation: BMC Cancer 2017 17:564
    Content type: Research article Published on:

  45. Previous studies have investigated the protective effect of vitamin D serum levels, at diagnosis and during the follow-up period after treatment, on melanoma outcome. In the present study we assess whether vit...

    Authors: J. De Smedt, S. Van Kelst, V. Boecxstaens, M. Stas, K. Bogaerts, D. Vanderschueren, C. Aura, K. Vandenberghe, D. Lambrechts, P. Wolter, O. Bechter, A. Nikkels, T. Strobbe, G. Emri, V. Marasigan and M. Garmyn
    Citation: BMC Cancer 2017 17:562
    Content type: Study protocol Published on:

  47. The effect of early palliative care and rehabilitation on the quality of life of patients with advanced cancer has been only sparsely described and needs further investigation. In the present trial we combine ...

    Authors: Lise Nottelmann, Mogens Groenvold, Tove Bahn Vejlgaard, Morten Aagaard Petersen and Lars Henrik Jensen
    Citation: BMC Cancer 2017 17:560
    Content type: Study protocol Published on:

  48. The global burden of hematologic malignancy (HM) is rapidly rising with aging, exposure to polluted environments, and global and local climate variability all being well-established conditions of oxidative str...

    Authors: Mireille Solange Nganga Nkanga, Benjamin Longo-Mbenza, Oladele Vincent Adeniyi, Jacques Bikaula Ngwidiwo, Antoine Lufimbo Katawandja, Paul Roger Beia Kazadi and Alain Nganga Nzonzila
    Citation: BMC Cancer 2017 17:559
    Content type: Research article Published on:

  49. Various studies have reported that the neutrophil-to-lymphocyte ratio in the serum (sNLR) may serve as a cost-effective and useful prognostic factor in patients with various cancer types. However, no study has...

    Authors: Yong Seok Lee, Hae-Seong Nam, Jun Hyeok Lim, Jung Soo Kim, Yeonsook Moon, Jae Hwa Cho, Jeong-Seon Ryu, Seung Min Kwak and Hong Lyeol Lee
    Citation: BMC Cancer 2017 17:557
    Content type: Research article Published on:

  50. The Empty Spiracles Homeobox (EMX-) 2 gene has been associated with regulation of growth and differentiation in neuronal development. While recent studies provide evidence that EMX2 regulates tumorigenesis of ...

    Authors: Berk Aykut, Markus Ochs, Praveen Radhakrishnan, Adrian Brill, Hermine Höcker, Sandra Schwarz, Daniel Weissinger, Roland Kehm, Yakup Kulu, Alexis Ulrich and Martin Schneider
    Citation: BMC Cancer 2017 17:555
    Content type: Research article Published on:

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