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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. With the development of sequencing technologies, there may be some disputes on sequencing analysis. The aim of this study was to investigate different allele frequency thresholds of mutations in targeted genes...

    Authors: Jie Ma, Yong Fu, Yao-yao Tu, Ying Liu, Yi-ran Tan, Wu-tong Ju, Curtis R. Pickering, Jeffrey N. Myers, Zhi-yuan Zhang and Lai-ping Zhong
    Citation: BMC Cancer 2018 18:758
    Content type: Research article Published on:

  2. Upper tract urothelial carcinoma (UTUC) is a tumor with sizable metastases and local recurrence. It has a worse prognosis than bladder cancer. This study was designed to investigate the urinary potential tumor...

    Authors: Chih-Ming Lu, Jen-Jie Lin, Han-Hsiang Huang, Ying-Chin Ko, Jue-Liang Hsu, Jiing-Chuan Chen, Zhong-Hao Din and Yu-Jen Wu
    Citation: BMC Cancer 2014 14:363
    Content type: Research article Published on:

  3. Nasal NK/T cell lymphoma is an aggressive disease and has a poor prognosis. Nasal NK/T cell lymphoma is refractory to conventional chemotherapy and has strong tendency of widespread relapse or dissemination in...

    Authors: Koh-ichi Sakata, Masanori Someya, Mutsuko Omatsu, Hiroko Asanuma, Tadashi Hasegawa, Masato Hareyama and Tetsuo Himi
    Citation: BMC Cancer 2007 7:229
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2008 8:45

  4. The efficacy of immunotherapy targeting the PD-1/PD-L1 pathway has previously been demonstrated in metastatic head and neck squamous cell carcinoma (HNSCC). Stereotactic Body Radiotherapy (SBRT) aims at ablati...

    Authors: Houda Bahig, Francine Aubin, John Stagg, Olguta Gologan, Olivier Ballivy, Eric Bissada, Felix-Phuc Nguyen-Tan, Denis Soulières, Louis Guertin, Edith Filion, Apostolos Christopoulos, Louise Lambert, Mustapha Tehfe, Tareck Ayad, Danielle Charpentier, Rahima Jamal…
    Citation: BMC Cancer 2019 19:68
    Content type: Study protocol Published on:

  5. As an H3K27me3 demethylase and counteracts polycomb-mediated transcription repression, KDM6B has been implicated in the development and malignant progression in various types of cancers. However, its potential...

    Authors: Mei Qin, Fei Han, Jian Wu, Feng-xia Gao, Yuan Li, De-xin Yan, Xue-mei He, Yang Long, Xiao-ping Tang, De-lian Ren, Yan Gao and Tian-yang Dai
    Citation: BMC Cancer 2021 21:559
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2021 21:893

  7. Exosomes are a new way of the communication between the tumor cell and macrophage in the micro-environment. The macrophage can be induced to different phenotypes according to the different tumors. In the prese...

    Authors: Jingting Wang, Nan Wang, Zeyu Zheng, Yanlu Che, Masanobu Suzuki, Satoshi Kano, Jianguang Lu, Peng Wang, Yanan Sun and Akihiro Homma
    Citation: BMC Cancer 2022 22:1208
    Content type: Research Published on:

  8. S100A1 expression is deregulated in a variety of human malignancies, but its role in normal and malignant endometrial cells is unclear.

    Authors: Mayu Nakagawa, Shyoma Higuchi, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Ako Yokoi, Yu Ishibashi, Takashi Ito and Makoto Saegusa
    Citation: BMC Cancer 2022 22:184
    Content type: Research Published on:

  9. Are twofold: 1) to estimate the relationship between obesity (BMI ≥30) and the prevalence of melanoma in different US states and 2) to examine the possibility of defining a new risk group. This might enhance t...

    Authors: Yuval Arbel, Yifat Arbel, Amichai Kerner and Miryam Kerner
    Citation: BMC Cancer 2023 23:178
    Content type: Research Published on:

  10. Neoadjuvant chemoradiation is not recommended as an approach for treatment of esophageal squamous cell carcinoma due to its significant postoperative mortality. However, it is assumed the combination of neoadj...

    Authors: Han Tang, Lijie Tan, Yaxing Shen, Hao Wang, Miao Lin, Mingxiang Feng, Songtao Xu, Weigang Guo, Cheng Qian, Tianshu Liu, Zhaochong Zeng, Yingyong Hou, Zhentao Yu, Hongjing Jiang, Zhigang Li, Chun Chen…
    Citation: BMC Cancer 2017 17:450
    Content type: Study protocol Published on:

  11. The platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) level are markers that have been reported to predict the histological type of various tumors, and here, we evaluated their utility in predict...

    Authors: Rui Chen, Liguang Wang, Qi Zhao, Zhen Li, Man Chen, Guodong Lian and Junyong Zhang
    Citation: BMC Cancer 2021 21:556
    Content type: Research article Published on:

  12. Tumor-infiltrating lymphocytes (TILs) are described as an important immune modulator in the tumor microenvironment and are associated with breast cancer (BC) outcome. The spatial analysis of TILs and TIL subty...

    Authors: Lisa König, Fabian D. Mairinger, Oliver Hoffmann, Ann-Kathrin Bittner, Kurt W. Schmid, Rainer Kimmig, Sabine Kasimir-Bauer and Agnes Bankfalvi
    Citation: BMC Cancer 2019 19:120
    Content type: Research article Published on:

  13. Overexpression of ubiquitin-conjugating enzyme 2C (UBE2C) has been detected in many types of human cancers, and is correlated with tumor malignancy. However, the role of UBE2C in human nasopharyngeal carcinoma...

    Authors: Zhihua Shen, Xiaofan Jiang, Chao Zeng, Shaojiang Zheng, Botao Luo, Yumei Zeng, Ranran Ding, Hanguo Jiang, Qiyi He, Junli Guo and Wei Jie
    Citation: BMC Cancer 2013 13:192
    Content type: Research article Published on:

  14. Poly (ADP-ribose) Polymerase (PARP) inhibitors are promising novel radiosensitisers. Pre-clinical models have demonstrated potent and tumour-specific radiosensitisation by PARP inhibitors. Olaparib is a PARP i...

    Authors: R. de Haan, E. van Werkhoven, M.M. van den Heuvel, H. M. U. Peulen, G. S. Sonke, P. Elkhuizen, M. W. M. van den Brekel, M. E. T. Tesselaar, C. Vens, J. H. M. Schellens, B. van Triest and M. Verheij
    Citation: BMC Cancer 2019 19:901
    Content type: Study protocol Published on:

  15. Numerous studies have highlighted that long non-coding RNAs (lncRNAs) can bind to microRNA (miRNA) sites as competing endogenous RNAs (ceRNAs), thereby affecting and regulating the expression of mRNAs and targ...

    Authors: Rui-Sheng Zhou, En-Xin Zhang, Qin-Feng Sun, Zeng-Jie Ye, Jian-Wei Liu, Dai-Han Zhou and Ying Tang
    Citation: BMC Cancer 2019 19:779
    Content type: Research article Published on:

  16. In the last decade many studies showed that the exhaled breath of subjects suffering from several pathological conditions has a peculiar volatile organic compound (VOC) profile. The objective of the present wo...

    Authors: Andrea Princivalle, Lorenzo Monasta, Giovanni Butturini, Claudio Bassi and Luigi Perbellini
    Citation: BMC Cancer 2018 18:529
    Content type: Research article Published on:

  17. Kallikreins have clinical value as prognostic markers in a subset of malignancies examined to date, including kallikrein 3 (prostate specific antigen) in prostate cancer. We previously demonstrated that kallik...

    Authors: Kristen L. Drucker, Caterina Gianinni, Paul A. Decker, Eleftherios P. Diamandis and Isobel A. Scarisbrick
    Citation: BMC Cancer 2015 15:565
    Content type: Research article Published on:

  18. Salivary gland cancer (SGC) is one of the common malignancies of the head and neck area. It develops in the minor and major salivary glands and sometimes metastasizes to other organs, particularly to the lungs...

    Authors: Tomoki Sumida, Ryuichi Murase, Akiko Onishi-Ishikawa, Sean D McAllister, Hiroyuki Hamakawa and Pierre-Yves Desprez
    Citation: BMC Cancer 2013 13:141
    Content type: Research article Published on:

  19. Osteosarcoma (OS) is the most common primary malignant bone tumors in children and adolescents. Large numbers of studies have focused on the long non-coding RNA (lncRNA) that plays essential roles in the progr...

    Authors: Zhen Wang, Yanting Wei, Hao Zhu, Lingfeng Yu, Jie Zhu, Qixiu Han, Ziying Liu, Jianhao Huang, Yan Zhu, Gentao Fan, Qikai Tang, Ji Qian, Xi Chen and Guangxin Zhou
    Citation: BMC Cancer 2022 22:728
    Content type: Research Published on:

  20. Primary systemic treatment for ovarian cancer is surgery, followed by platinum based chemotherapy. Platinum resistant cancers progress/recur in approximately 25% of cases within six months. We aimed to identif...

    Authors: Zsófia Pénzváltó, András Lánczky, Julianna Lénárt, Nóra Meggyesházi, Tibor Krenács, Norbert Szoboszlai, Carsten Denkert, Imre Pete and Balázs Győrffy
    Citation: BMC Cancer 2014 14:837
    Content type: Research article Published on:

  21. Esophageal squamous cell carcinoma (ESCC) is a global public health issue, as it is the eighth most common cancer worldwide. The mechanisms behind ESCC invasion and progression are still poorly understood, and...

    Authors: Holli A. Loomans, Shanna A. Arnold, Laura L. Quast and Claudia D. Andl
    Citation: BMC Cancer 2016 16:873
    Content type: Research article Published on:

  22. This systematic review and meta-analysis aimed to determine the potential value of neutrophil to lymphocyte ratio (NLR) as an assessment tool in the clinical distinction between uterine sarcoma and uterine lei...

    Authors: Fatemeh Tabatabaei, Saghar Babadi, Shima Nourigheimasi, Arshin Ghaedi, Monireh Khanzadeh, Aida Bazrgar, Morad Kohandel Gargari and Shokoufeh Khanzadeh
    Citation: BMC Cancer 2024 24:12
    Content type: Research Published on:

  23. Although anaplastic lymphoma kinase (ALK) is overexpressed in several primary solid tumor types, its role in endometrial carcinoma (Em Ca) remains unclear.

    Authors: Ako Yokoi, Yusaku Nakamura, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Mayu Nakagawa, Yu Ishibashi, Takashi Ito, Kensuke Ohhigata, Youhei Harada, Naomi Fukagawa and Makoto Saegusa
    Citation: BMC Cancer 2023 23:765
    Content type: Research Published on:

  24. Wolf-Hirschhorn syndrome candidate gene-1 (WHSC1), a histone methyltransferase, has been found to be upregulated and its expression to be correlated with expression of enhancer of zeste homolog 2 (EZH2) in sev...

    Authors: Machiko Kojima, Kenbun Sone, Katsutoshi Oda, Ryuji Hamamoto, Syuzo Kaneko, Shinya Oki, Asako Kukita, Hidenori Machino, Harunori Honjoh, Yoshiko Kawata, Tomoko Kashiyama, Kayo Asada, Michihiro Tanikawa, Mayuyo Mori-Uchino, Tetsushi Tsuruga, Kazunori Nagasaka…
    Citation: BMC Cancer 2019 19:455
    Content type: Research article Published on:

  25. Thymic carcinoma is a rare cancer with minimal evidence of a survival benefit following chemotherapy. An oral fluoropyrimidine of S-1, however, is the recommended active cytotoxic chemotherapy agent for refrac...

    Authors: Yusuke Okuma, Yukio Hosomi, Shingo Miyamoto, Masahiko Shibuya, Tatsuru Okamura and Tsunekazu Hishima
    Citation: BMC Cancer 2016 16:156
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2016 16:272

  26. The in vivo functions of SerpinB2 in tumor cells and tumor-associated macrophages (TAMs) during breast cancer development and metastasis remain elusive. SerpinB2-deficient MMTV-PyMT mice (PyMTSB2−/−) were previou...

    Authors: Yin Ji Piao, Hoe Suk Kim, Hyelim Kim, Jun Shen and Woo Kyung Moon
    Citation: BMC Cancer 2024 24:792
    Content type: Research Published on:

  27. The dysregulation of miR-663a is frequently observed in many human cancers. However, the functional role and precise mechanism of miR-663a have been controversial in hepatocellular carcinoma (HCC) and need to ...

    Authors: Chengshuo Zhang, Baomin Chen, Ao Jiao, Feng Li, Ning Sun, Guoqing Zhang and Jialin Zhang
    Citation: BMC Cancer 2018 18:1179
    Content type: Research article Published on:

  28. In view of the prominent role in cancer cell biology and alteration in substantial numbers of ESCC, defining EGFR molecular characteristics relevant to patient prognosis is of great importance. Therefore, we a...

    Authors: Dongxian Jiang, Xiaojing Li, Haixing Wang, Yuan Shi, Chen Xu, Shaohua Lu, Jie Huang, Yifan Xu, Haiying Zeng, Jieakesu Su, Yingyong Hou and Lijie Tan
    Citation: BMC Cancer 2015 15:377
    Content type: Research article Published on:

  30. In the era of cytokines, patients with brain metastases (BM) from renal cell carcinoma had a significantly shorter survival than patients without. Targeted agents (TA) have improved the outcome of patients wit...

    Authors: Ursula M Vogl, Marija Bojic, Wolfgang Lamm, Josa M Frischer, Oskar Pichelmayer, Gero Kramer, Andrea Haitel, Klaus Kitz, Kaan Harmankaya, Christoph C Zielinski and Manuela Schmidinger
    Citation: BMC Cancer 2010 10:480
    Content type: Research article Published on:

  31. NUT carcinoma (NC), previously known as NUT midline carcinoma, is a rare and very aggressive cancer that occurs in both children and adults. NC is largely chemoresistant, with an overall survival of less than ...

    Authors: Tina Carter, Maxine Crook, Ashleigh Murch, Alex H. Beesley, Nick de Klerk, Adrian Charles and Ursula R. Kees
    Citation: BMC Cancer 2021 21:740
    Content type: Research article Published on:

  32. Many patients diagnosed with oesophageal adenocarcinoma (OAC) present with advanced disease and approximately half present with metastatic disease. Patients with localised disease, who are managed with curativ...

    Authors: Becky A. S. Bibby, Cecelia S. Miranda, John V. Reynolds, Christopher J. Cawthorne and Stephen G. Maher
    Citation: BMC Cancer 2019 19:784
    Content type: Research article Published on:

  33. In a previous study utilizing mass spectrometry-based proteomics, we identified calcium-activated chloride channel regulator 1 (CLCA1) as a potential tumor suppressor in pancreatic cancer and the expression wa...

    Authors: Dingyuan Hu, Daniel Ansari, Qimin Zhou, Agata Sasor, Katarzyna Said Hilmersson, Monika Bauden, Yi Jiang and Roland Andersson
    Citation: BMC Cancer 2018 18:1096
    Content type: Research article Published on:

  34. Two ROS1 tyrosine kinase inhibitors have been approved for ROS1 fusion positive (ROS1+) non-small cell lung cancer (NSCLC) tumors. We performed a pan-tumor analysis of the incidence of ROS1 fusions to assess if m...

    Authors: Misako Nagasaka, Shannon S. Zhang, Yasmine Baca, Joanne Xiu, Jorge Nieva, Ari Vanderwalde, Jeffrey J. Swensen, David Spetzler, Wolfgang Michael Korn, Luis E. Raez, Stephen V. Liu and Sai-Hong Ignatius Ou
    Citation: BMC Cancer 2023 23:1000
    Content type: Research Published on:

  35. Pembrolizumab is effective as first-line therapy against advanced non-small cell lung cancer (NSCLC) in patients with programmed death ligand-1 (PD-L1) expression levels ≥50% [1]. However, it is not effective ...

    Authors: Mitsunori Morita, Motohiro Tamiya, Daichi Fujimoto, Akihiro Tamiya, Hidekazu Suzuki, Katsuya Hirano, Yasushi Fukuda, Toshihide Yokoyama, Ryota Kominami, Masaki Kanazu, Junji Uchida, Satoshi Hara, Shuji Yamashita and Hiromi Tomioka
    Citation: BMC Cancer 2020 20:93
    Content type: Research article Published on:

  36. Epidermal growth factor-like domain 7 (Egfl7), a recently identified secreted protein, was significantly increased in patients with HCC by our previous studies. However, its efficacy in the diagnosis of early ...

    Authors: Meng-Yuan Yang, Fan Wu, Feng Fang, Hao Yang, Jing-Fan Zhang, Guo-Dong Chen and Lian-Yue Yang
    Citation: BMC Cancer 2021 21:772
    Content type: Research Published on:

  37. Hürthle cell thyroid carcinoma (HCTC) is a rare disease. It is believed that it is more aggressive than follicular thyroid carcinoma. The aim of our study was to identify factors associated with disease-specif...

    Authors: Rok Petric, Barbara Gazic and Nikola Besic
    Citation: BMC Cancer 2014 14:777
    Content type: Research article Published on:

  39. Human Cripto-1, a member of the EGF-CFC family, is indispensable for early embryonic development. Cripto-1 plays an important oncogenic role during tumorigenesis and is overexpressed in a wide range of epithel...

    Authors: Zhengrong Wu, Gang Li, Lirong Wu, Desheng Weng, Xiangping Li and Kaitai Yao
    Citation: BMC Cancer 2009 9:315
    Content type: Research article Published on:

  40. Neuroendocrine tumors (NETs) of the esophagus are extremely rare, and few cases have been reported worldwide. Thus, a comprehensive nationwide study is needed to understand the characteristics of and treatment...

    Authors: Chang Geun Lee, Yun Jeong Lim, Seun Ja Park, Byung Ik Jang, Seok Reyol Choi, Jae Kwang Kim, Yong-Tae Kim, Joo Young Cho, Chang Hun Yang, Hoon Jai Chun and Si Young Song
    Citation: BMC Cancer 2014 14:569
    Content type: Research article Published on:

  41. To identify predictors of prolonged or shortened progression-free survival (PFS) and overall survival (OS) among patients with metastatic renal cell carcinoma (mRCC) who received first-line targeted therapies.

    Authors: Sung Han Kim, Sohee Kim, Jungnam Joo, Ho Kyung Seo, Jae Young Joung, Kang Hyun Lee and Jinsoo Chung
    Citation: BMC Cancer 2016 16:577
    Content type: Research article Published on:

  42. The aim of this study was to investigate the epidemiological characteristics and associated risk factors of recurrent lower-grade glioma [LGG] (WHO grades II and III) according to the 2016 updated WHO classifi...

    Authors: Ruolun Wei, Chao Zhao, Jianguo Li, Fengdong Yang, Yake Xue and Xinting Wei
    Citation: BMC Cancer 2022 22:114
    Content type: Research Published on:

  43. Mutations in the KRAS gene are one of the most frequent genetic abnormalities in ovarian carcinoma. They are of renewed interest as new epidermal growth factor receptor (EGFR)-targeted therapies are being investi...

    Authors: Veronika Auner, Gernot Kriegshäuser, Dan Tong, Reinhard Horvat, Alexander Reinthaller, Alexander Mustea and Robert Zeillinger
    Citation: BMC Cancer 2009 9:111
    Content type: Research article Published on:

  44. The discovery of new anti-melanoma drugs with low side effect is urgently required in the clinic. Recent studies showed that morusin, a flavonoid compound isolated from the root bark of Morus Alba, has the pot...

    Authors: Wei Liu, Yacong Ji, Feng Wang, Chongyang Li, Shaomin Shi, Ruochen Liu, Qian Li, Leiyang Guo, Yaling Liu and Hongjuan Cui
    Citation: BMC Cancer 2023 23:602
    Content type: Research Published on:

  45. To evaluate survival rates of hepatocellular carcinoma (HCC), the Chiang Mai Cancer Registry provided characteristics data of 6276 HCC patients diagnosed between 1998-2020 based on evolution of imaging diagnos...

    Authors: Nawapon Nakharutai, Imjai Chitapanarux, Patrinee Traisathit, Pimwarat Srikummoon, Suwalee Pojchamarnwiputh, Nakarin Inmutto and Wittanee Na Chiangmai
    Citation: BMC Cancer 2023 23:1063
    Content type: Research Published on:

  46. Pituitary tumor-transforming gene (PTTG) is an oncogene that is overexpressed in variety of tumors and exhibits characteristics of a transforming gene. Previous transgenic mouse models to access the tumorigeni...

    Authors: Miranda Y Fong, Hanan Farghaly and Sham S Kakar
    Citation: BMC Cancer 2012 12:532
    Content type: Research article Published on:

  47. The metabolism of cancer cells is often reprogrammed by dysregulation of metabolic enzymes. Transketolase-like 1 (TKTL1) is a homodimeric transketolase linking the pentose-phosphate pathway with the glycolytic...

    Authors: Aparna Jayachandran, Pu-Han Lo, Anderly C. Chueh, Prashanth Prithviraj, Ramyar Molania, Mercedes Davalos-Salas, Matthew Anaka, Marzena Walkiewicz, Jonathan Cebon and Andreas Behren
    Citation: BMC Cancer 2016 16:134
    Content type: Research article Published on:

  49. The deregulated alternative splicing of key glycolytic enzyme, Pyruvate Kinase muscle isoenzyme (PKM) is implicated in metabolic adaptation of cancer cells. The splicing switch from normal PKM1 to cancer-speci...

    Authors: Sandhya Yadav, Somnath D. Bhagat, Amit Gupta, Atul Samaiya, Aasheesh Srivastava and Sanjeev Shukla
    Citation: BMC Cancer 2019 19:1031
    Content type: Research article Published on:

  50. DNA damage repair genes JWA, XRCC1 and BRCA1 were associated with clinical outcomes and could convert the response to the cisplatin-based therapy in some carcinomas. The synergistic effects of JWA, XRCC1 and B...

    Authors: Bin Wei, Qin Han, Lijuan Xu, Xiaohui Zhang, Jing Zhu, Li Wan, Yan Jin, Zhaoye Qian, Jingjing Wu, Yong Gao, Jianwei Zhou and Xiaofei Chen
    Citation: BMC Cancer 2015 15:331
    Content type: Research article Published on:

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