Skip to main content

Articles

3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 65 of 79

  1. Additive/adjuvant chemotherapy as concept after local treatment of colorectal metastases has not been proven to be successful by phase III trials. Accordingly, a standard of care to improve relapse rates and l...

    Authors: Nathanael Raschzok, Sebastian Stintzing, Volker Heinemann, Geraldine Rauch, Jens Ricke, Matthias Guckenberger, Annika Kurreck, Annabel H. S. Alig, Arndt Stahler, Lars Bullinger, Moritz Schmelzle, Wenzel Schöning, Georg Lurje, Felix Krenzien, Oliver Haase, Beate Rau…
    Citation: BMC Cancer 2022 22:359
    Content type: Study protocol Published on:

  2. In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have increased significantly. The screening and identification of rel...

    Authors: Aiqin Zhao, Yunzhi Pan, Yingyin Gao, Zheng Zhi, Haiying Lu, Bei Dong, Xuan Zhang, Meiying Wu, Fenxia Zhu, Sufang Zhou and Sai Ma
    Citation: BMC Cancer 2024 24:559
    Content type: Research Published on:

  3. Cancers of the head and neck region are often characterized by locally advanced, non-metastatic disease. Standard treatments for advanced cervico-facial cancers of the skin or primary head and neck squamous ce...

    Authors: Justin Lee, Nhu Tram Nguyen, James Wright, Ka-Kit David Yeung, Stephen Sagar, Do-Hoon Kim, Orest Ostapiak, Lilian Doerwald-Munoz and Timothy Whelan
    Citation: BMC Cancer 2023 23:379
    Content type: Study protocol Published on:

  4. AMP-activated protein kinase (AMPK) has recently been considered as a potential target for cancer therapy. However, the expression status of various subunits of the heterotrimeric AMPK in human cancers is rarely...

    Authors: Cuilan Li, Vincent WS Liu, Pui M Chiu, David W Chan and Hextan YS Ngan
    Citation: BMC Cancer 2012 12:357
    Content type: Research article Published on:

  5. The role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular carcinoma (HCC) remains uncertain. The aim of this study was to assess th...

    Authors: Kaiquan Huang, Tao Qian, Wen Chen, Mengyi Lao, Huiliang Li, Wei-Chiao Lin, Bryan Wei Chen, Xueli Bai, Shunliang Gao, Tao Ma and Tingbo Liang
    Citation: BMC Cancer 2024 24:620
    Content type: Research Published on:

  6. FOLFOX second-line treatment seems to be a validated option for patients with pancreatic cancer (PC) progressing after gemcitabine chemotherapy. However, other therapeutics strategy has developed in first-line...

    Authors: Aziz Zaanan, Isabelle Trouilloud, Theofano Markoutsaki, Mélanie Gauthier, Anne-Claire Dupont-Gossart, Thierry Lecomte, Thomas Aparicio, Pascal Artru, Anne Thirot-Bidault, Fanny Joubert, Daniella Fanica and Julien Taieb
    Citation: BMC Cancer 2014 14:441
    Content type: Research article Published on:

  7. Activation of the protein kinase B/mammalian target of rapamycin (AKT/mTOR) pathway has been demonstrated to be involved in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated tumorigenesis in anaplast...

    Authors: Ju Gao, Minzhi Yin, Yiping Zhu, Ling Gu, Yanle Zhang, Qiang Li, Cangsong Jia and Zhigui Ma
    Citation: BMC Cancer 2013 13:471
    Content type: Research article Published on:

  8. P-cadherin (P-cad) is a transmembrane molecule involved in the cell-cell adhesion and similar to E-cadherin (E-cad), but less investigated in oncology, especially in in vivo studies. Aims of the present study wer...

    Authors: Lorenzo Lo Muzio, Giuseppina Campisi, Antonio Farina, Corrado Rubini, Giuseppe Pannone, Rosario Serpico, Gregorio Laino, Alfredo De Lillo and Francesco Carinci
    Citation: BMC Cancer 2005 5:63
    Content type: Research article Published on:

  9. In menopausal women, one of the critical risk factors for breast cancer is obesity/adiposity. It is evident from various studies that leptin, a 16 kDa protein hormone overproduced in obese people, plays the cr...

    Authors: Inamul Haque, Arnab Ghosh, Seth Acup, Snigdha Banerjee, Kakali Dhar, Amitabha Ray, Sandipto Sarkar, Suman Kambhampati and Sushanta K. Banerjee
    Citation: BMC Cancer 2018 18:99
    Content type: Research article Published on:

  10. Aspiration pneumonia is one of the most important side effects of chemoradiotherapy (CRT) and bio-radiotherapy (BRT) in patients with head and neck cancer (HNC). Aspiration pneumonia can lead to cancer-related...

    Authors: Hiromichi Shirasu, Tomoya Yokota, Satoshi Hamauchi, Yusuke Onozawa, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Keita Mori and Hirofumi Yasui
    Citation: BMC Cancer 2020 20:182
    Content type: Research article Published on:

  11. The E-selectin ligands expressed by cancer cells mediate adhesion of circulating cancer cells to endothelial cells, as well as within tissue microenvironments important for tumor progression and metastasis. Th...

    Authors: Mylène A. Carrascal, Catarina Talina, Paula Borralho, A. Gonçalo Mineiro, Ana Raquel Henriques, Cláudia Pen, Manuela Martins, Sofia Braga, Robert Sackstein and Paula A. Videira
    Citation: BMC Cancer 2018 18:495
    Content type: Technical advance Published on:

  12. The malignant pleural mesothelioma (MPM) response rate to chemotherapy is low. The identification of imaging biomarkers that could help guide the most effective therapy approach for individual patients is high...

    Authors: Martina Vivoda Tomšič, Peter Korošec, Viljem Kovač, Sotirios Bisdas and Katarina Šurlan Popovič
    Citation: BMC Cancer 2022 22:191
    Content type: Research article Published on:

  13. The search of useful serum biomarkers for the early detection of cervical cancers has been of a high priority. The activation of Macrophage-Colony Stimulating Factor (M-CSF) and Vascular Endothelial Growth Fac...

    Authors: Iwona Sidorkiewicz, Monika Zbucka-Krętowska, Kamil Zaręba, Emilia Lubowicka, Monika Zajkowska, Maciej Szmitkowski, Ewa Gacuta and Sławomir Ławicki
    Citation: BMC Cancer 2019 19:398
    Content type: Research article Published on:

  14. The Screening Inventory of Psychosocial Problems (SIPP) is a short, validated self-reported questionnaire to identify psychosocial problems in Dutch cancer patients. The one-page 24-item questionnaire assesses...

    Authors: Anna PBM Braeken, Lilian Lechner, Francis CJM van Gils, Ruud MA Houben, Daniëlle Eekers, Ton Ambergen and Gertrudis IJM Kempen
    Citation: BMC Cancer 2009 9:177
    Content type: Study protocol Published on:

  15. There is limited epidemiologic data on patients with acute myelogenous (myeloid) leukemia (AML) requiring life-sustaining therapies in the intensive care unit (ICU). Our objectives were to describe the clinica...

    Authors: Amanda L Roze des Ordons, Kris Chan, Imran Mirza, Derek R Townsend and Sean M Bagshaw
    Citation: BMC Cancer 2010 10:516
    Content type: Research article Published on:

  16. Neuroendocrine tumors (NETs) are heterogeneous, widely distributed tumors arising from neuroendocrine cells. Gastrointestinal (GI)-NETs are the most common and NETs of the rectum represent 15, 2% of gastrointe...

    Authors: Gemma Bruera, Antonio Giuliani, Lucia Romano, Alessandro Chiominto, Alessandra Di Sibio, Stefania Mastropietro, Pierluigi Cosenza, Enrico Ricevuto, Mario Schietroma and Francesco Carlei
    Citation: BMC Cancer 2019 19:960
    Content type: Case report Published on:

  17. Glucose regulated protein 78 (Grp78) is involved in the invasion and metastasis in many human cancers including gastric cancer, breast cancer, prostate cancer. But the role of Grp78 in the invasion of human he...

    Authors: Rongjian Su, Zhen Li, Hongdan Li, Huijuan Song, Cuifen Bao, Jia Wei and Liufang Cheng
    Citation: BMC Cancer 2010 10:20
    Content type: Research article Published on:

  18. CDCP1, a transmembrane protein with tumor pro-metastatic activity, was recently identified as a prognostic marker in TNBC, the most aggressive breast cancer subtype still lacking an effective molecular targete...

    Authors: Luca Forte, Federica Turdo, Cristina Ghirelli, Piera Aiello, Patrizia Casalini, Marilena Valeria Iorio, Elvira D’Ippolito, Patrizia Gasparini, Roberto Agresti, Beatrice Belmonte, Gabriella Sozzi, Lucia Sfondrini, Elda Tagliabue, Manuela Campiglio and Francesca Bianchi
    Citation: BMC Cancer 2018 18:586
    Content type: Research article Published on:

  19. Using propensity score matching method (PSM) to evaluate the feasibility and clinical outcomes of simultaneous modulated accelerated radiation therapy (SMART) using helical tomotherapy (HT) in patients with na...

    Authors: Lei Du, Xin-Xin Zhang, Lin-Chun Feng, Bao-Lin Qu, Jing Chen, Jun Yang, Hai-Xia Liu, Shou-Ping Xu, Chuan-Bin Xie and Lin Ma
    Citation: BMC Cancer 2017 17:582
    Content type: Research article Published on:

  21. Papillary and follicular thyroid carcinomas can be treated surgically and with radioiodine therapy, whereas therapeutic options for advanced stage IV medullary and for anaplastic tumours are limited. Recently,...

    Authors: Max Czajkowski, Daniel Kaemmerer, Jörg Sänger, Guido Sauter, Ralph M. Wirtz, Stefan Schulz and Amelie Lupp
    Citation: BMC Cancer 2022 22:740
    Content type: Research Published on:

  22. Recent randomized controlled trials comparing neoadjuvant chemoradiation plus surgery or perioperative chemotherapy plus surgery with surgery alone showed significant survival benefits for combined modality tr...

    Authors: Jens Hoeppner, Florian Lordick, Thomas Brunner, Torben Glatz, Peter Bronsert, Nadine Röthling, Claudia Schmoor, Dietmar Lorenz, Christian Ell, Ulrich T. Hopt and J. Rüdiger Siewert
    Citation: BMC Cancer 2016 16:503
    Content type: Study protocol Published on:

  23. Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adi...

    Authors: Genevra Kuziel, Brittney N. Moore, Grace P. Haugstad, Yue Xiong, Abbey E. Williams and Lisa M. Arendt
    Citation: BMC Cancer 2023 23:1183
    Content type: Research Published on:

  24. Caveolin-1 (CAV1) has been implicated both in tumor suppression and progression, whereby the specific role appears to be context dependent. Endometrial cancer is one of the most common malignancies of the fema...

    Authors: Natalia Diaz-Valdivia, Denisse Bravo, Hernán Huerta, Soledad Henriquez, Fernando Gabler, Margarita Vega, Carmen Romero, Claudia Calderon, Gareth I. Owen, Lisette Leyton and Andrew F. G. Quest
    Citation: BMC Cancer 2015 15:463
    Content type: Research article Published on:

  25. A number of studies have reported hyperprogressive disease (HPD) in non-small cell lung cancer (NSCLC) after treatment with immune checkpoint inhibitor (ICI). This study aimed to summarize the incidence and su...

    Authors: Yan Chen, Junjie Hu, Fangfang Bu, Haiping Zhang, Ke Fei and Peng Zhang
    Citation: BMC Cancer 2020 20:707
    Content type: Research article Published on:

  26. Colorectal cancer is a heterogeneous group of malignancies with complex molecular subtypes. While colon cancer has been widely investigated, studies on rectal cancer are very limited. Here, we performed multi-...

    Authors: Mingshan Liu, Yang Liu, Jiabo Di, Zhe Su, Hong Yang, Beihai Jiang, Zaozao Wang, Meng Zhuang, Fan Bai and Xiangqian Su
    Citation: BMC Cancer 2017 17:787
    Content type: Research article Published on:

  27. Zinc-finger E-box binding homeobox 1 (ZEB-1) plays crucial roles in epithelial-to-mesenchymal transition during tumor carcinogenesis. Published studies have examined the potential value of ZEB-1 as a biomarker...

    Authors: Borong Chen, Baisheng Chen, Zhipeng Zhu, Weipeng Ye, Junjie Zeng, Gang Liu, Shengjie Wang, Jin Gao, Guoxing Xu and Zhengjie Huang
    Citation: BMC Cancer 2019 19:635
    Content type: Research article Published on:

  28. c-Met is the receptor tyrosine kinase for hepatocyte growth factor (HGF) encoded by the MET proto-oncogene. Aberrant activation of c-Met resulting from MET amplification and c-Met overexpression is associated wit...

    Authors: Jieyi Wang, Liliane Goetsch, Lora Tucker, Qian Zhang, Alexandra Gonzalez, Kedar S. Vaidya, Anatol Oleksijew, Erwin Boghaert, Minghao Song, Irina Sokolova, Ekaterina Pestova, Mark Anderson, William N. Pappano, Peter Ansell, Anahita Bhathena, Louie Naumovski…
    Citation: BMC Cancer 2016 16:105
    Content type: Research article Published on:

  29. Preoperative chemoradiotherapy (pre-CRT) followed by total mesorectal excision (TME) is currently a standard therapy for locally advanced mid-to-low rectal cancer. Less aggressive, organ-preserving option such...

    Authors: Jong Lyul Lee, Seok-Byung Lim, Chang Sik Yu, In Ja Park, Yong Sik Yoon, Chan Wook Kim, Seong Ho Park, Jong Seok Lee, Yong Sang Hong, Sun Young Kim, Jeong Eun Kim, Jong Hoon Kim, Jin-hong Park, Jihun Kim and Minkyu Han
    Citation: BMC Cancer 2019 19:404
    Content type: Study protocol Published on:

  30. Recently, we introduced Stroma-AReactive-Invasion-Front-Areas (SARIFA) as a novel hematoxylin–eosin (H&E)-based histopathologic prognostic biomarker for various gastrointestinal cancers, closely related to lip...

    Authors: Johanna S. Enke, Matthias Groß, Bianca Grosser, Eva Sipos, Julie Steinestel, Phillip Löhr, Johanna Waidhauser, Constantin Lapa, Bruno Märkl and Nic G. Reitsam
    Citation: BMC Cancer 2024 24:65
    Content type: Research Published on:

  31. In Europe, gastric cancer remains diagnosed at advanced stage (serosal and/or lymph node involvement). Despite curative management combining perioperative systemic chemotherapy and gastrectomy with D1-D2 lymph...

    Authors: Olivier Glehen, Guillaume Passot, Laurent Villeneuve, Delphine Vaudoyer, Sylvie Bin-Dorel, Gilles Boschetti, Eric Piaton and Alfredo Garofalo
    Citation: BMC Cancer 2014 14:183
    Content type: Study protocol Published on:

  33. The objective of this study was to discover and to validate novel noninvasive biomarkers that distinguish between benign prostate hyperplasia (BPH) and localized prostate cancer (PCa), thereby helping to solve...

    Authors: Andrej Jedinak, Adam Curatolo, David Zurakowski, Simon Dillon, Manoj K Bhasin, Towia A Libermann, Roopali Roy, Monisha Sachdev, Kevin R Loughlin and Marsha A Moses
    Citation: BMC Cancer 2015 15:259
    Content type: Research article Published on:

  34. Synchronous multiple primary malignant tumors (sMPMTs) are sometimes diagnosed in patients with malignant lymphoma. We herein investigated the prognostic impact of sMPMT in lymphoma patients and the optimal tr...

    Authors: Yu Yagi, Yusuke Kanemasa, Yuki Sasaki, An Ohigashi, Yuka Morita, Taichi Tamura, Shohei Nakamura, Akihiko Kageyama, Yasushi Omuro and Tatsu Shimoyama
    Citation: BMC Cancer 2022 22:640
    Content type: Research Published on:

  35. Metaplastic carcinoma, an uncommon subtype of breast cancer, is part of the spectrum of basal-like, triple receptor-negative breast carcinomas. The present study examined 20 surgical specimens of metaplastic b...

    Authors: Roberto Herrera-Goepfert, Teresa Vela-Chávez, Adela Carrillo-García, Marcela Lizano-Soberón, Alfredo Amador-Molina, Luis F Oñate-Ocaña and Rita Sotelo-Regil Hallmann
    Citation: BMC Cancer 2013 13:445
    Content type: Research article Published on:

  36. Esophageal squamous cell carcinoma (ESCC) remains one of the most lethal cancers worldwide accompany with an extremely poor prognosis. Therefore, this study aims to screen for new molecules affecting ESCC and ...

    Authors: Yanqun Liu, Rong Xiong, Ting Xiao, Li Xiong, Jialin Wu, Junfeng Li, Gang Feng, Guiqin Song and Kang Liu
    Citation: BMC Cancer 2022 22:1304
    Content type: Research Published on:

  37. Combination therapy of irinotecan, folinic acid (FA) and 5-fluorouracil (5-FU) has been proven to be highly effective for the treatment of metastatic colorectal cancer. However, in light of safety and efficacy...

    Authors: Andreas Teufel, Silke Steinmann, Jürgen Siebler, Christiane Zanke, Herbert Hohl, Bernd Adami, M Schroeder, O Klein, Thomas Höhler, Peter R Galle, Michael Heike and Markus Moehler
    Citation: BMC Cancer 2004 4:38
    Content type: Research article Published on:

  38. Integrator complex subunit 6 (INTS6) was found to play a tumour suppressing role in certain types of solid tumours. In this study, we wanted to determine the expression level of INTS6 in hepatocellular carcino...

    Authors: Ka Yin Lui, Hui Zhao, Chunhui Qiu, Chuo Li, Zhigang Zhang, Haoran Peng, Rongdang Fu, Hu-an Chen and Min-qiang Lu
    Citation: BMC Cancer 2017 17:644
    Content type: Research article Published on:

  40. Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The p...

    Authors: Akira Maekawa, Kenichi Kohashi, Masaaki Kuda, Kunio Iura, Takeaki Ishii, Makoto Endo, Tetsuya Nakatsura, Yukihide Iwamoto and Yoshinao Oda
    Citation: BMC Cancer 2016 16:511
    Content type: Research article Published on:

  41. The overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer is a poor prognosis. Trastuzumab improves overall survival but is associated with cardiotoxicity, especially a decline in ...

    Authors: Quentin Jacquinot, Nathalie Meneveau, Marion Chatot, Franck Bonnetain, Bruno Degano, Malika Bouhaddi, Gilles Dumoulin, Dewi Vernerey, Xavier Pivot and Fabienne Mougin
    Citation: BMC Cancer 2017 17:425
    Content type: Study protocol Published on:

  43. Chromosomal and genomic aberrations are common features of human cancers. However, chromosomal numerical and structural aberrations, breakpoints and disrupted genes have yet to be identified in esophageal squa...

    Authors: Jia-Jie Hao, Zhi-Zhou Shi, Zhi-Xin Zhao, Yu Zhang, Ting Gong, Chun-Xiang Li, Ting Zhan, Yan Cai, Jin-Tang Dong, Song-Bin Fu, Qi-Min Zhan and Ming-Rong Wang
    Citation: BMC Cancer 2012 12:367
    Content type: Research article Published on:

  44. Patients with primary cutaneous melanomas that are ulcerated and >2 mm in thickness, >4 mm in thickness and those with nodal micrometastases at diagnosis, have few options for adjuvant treatment. Recent studie...

    Authors: Robyn PM Saw, Bruce K Armstrong, Rebecca S Mason, Rachael L Morton, Kerwin F Shannon, Andrew J Spillane, Jonathan R Stretch and John F Thompson
    Citation: BMC Cancer 2014 14:780
    Content type: Study protocol Published on:

  45. Prognosis of esophageal cancer is poor despite curative surgery. The chemokine receptor CXCR4 has been proposed to distinctly contribute to tumor growth, dissemination and local immune escape in a limited numb...

    Authors: Ines Gockel, Carl C Schimanski, Christian Heinrich, T Wehler, K Frerichs, Daniel Drescher, Christian von Langsdorff, Mario Domeyer, Stefan Biesterfeld, Peter R Galle, Theodor Junginger and Markus Moehler
    Citation: BMC Cancer 2006 6:290
    Content type: Research article Published on:

  46. Epigenetic alterations contribute greatly to the development and progression of colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study aimed to discover miR-622 regulat...

    Authors: Yuehong Chen, Feng Liu, Xinhua Chen, Wenyi Li, Kejun Li, Hailang Cai, Shunyi Wang, Honglei Wang, Ke Xu, Chenxi Zhang, Shengzhi Ye, Yunhao Shen, Tingyu Mou, Shumin Cai, Jianwei Zhou and Jiang Yu
    Citation: BMC Cancer 2024 24:26
    Content type: Research Published on:

  47. This prospective, open-label phase II study assessed the impact of liver-directed therapy with selective internal radiation therapy (SIRT) and systemic chemotherapy on progression-free survival (PFS) in liver-...

    Authors: Peter Gibbs, Cuong Do, Lara Lipton, David N. Cade, Michael J. Tapner, David Price, Geoff D. Bower, Richard Dowling, Meir Lichtenstein and Guy A. van Hazel
    Citation: BMC Cancer 2015 15:802
    Content type: Research article Published on:

  48. Treatment options for patients with locally advanced pancreatic cancer include surgery, chemotherapy as well as radiotherapy. In many cases, surgical resection is not possible, and therefore treatment alternat...

    Authors: Stephanie E Combs, Daniel Habermehl, Meinhard Kieser, Constantin Dreher, Jens Werner, Renate Haselmann, Oliver Jäkel, Dirk Jäger, Markus W Büchler and Jürgen Debus
    Citation: BMC Cancer 2013 13:419
    Content type: Study protocol Published on:

  49. C-reactive protein (CRP) is considered a useful serum marker for patients with RCC. However, its clinical utility in advanced metastatic renal cell carcinoma (AM-RCC), particularly in deciding whether to perfo...

    Authors: Hiroki Ito, Koichi Shioi, Takayuki Murakami, Akitoshi Takizawa, Futoshi Sano, Takashi Kawahara, Nobuhiko Mizuno, Kazuhide Makiyama, Noboru Nakaigawa, Takeshi Kishida, Takeshi Miura, Yoshinobu Kubota and Masahiro Yao
    Citation: BMC Cancer 2012 12:337
    Content type: Research article Published on:

  50. Nasopharyngeal carcinoma (NPC) is a type of head-neck cancer with a distinguishable geographic and racial distribution worldwide. Increasing evidence supports that the accumulation of additional genetic and ep...

    Authors: Pei-Yu Huang, Ting-Ting Zeng, Xiaojiao Ban, Meng-Qing Li, Bao-Zhu Zhang, Ying-Hui Zhu, Wen-Feng Hua, Hai-Qiang Mai, Li Zhang, Xin-Yuan Guan and Yan Li
    Citation: BMC Cancer 2016 16:669
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us