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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 63 of 79

  1. Primary small cell carcinoma of the esophagus (PSCCE) is a rare and aggressive tumor with poor prognosis. The aim of this study was to investigate the existence of EGFR, KRAS, PIK3CA and PTEN mutations in PSCCE.

    Authors: Zhimin Zhang, Hualiang Xiao, Fei Xie, Hui Zhang, Chuan Chen, He Xiao, Zhenzhou Yang, Dong Wang, Zengpeng Li and Ge Wang
    Citation: BMC Cancer 2014 14:19
    Content type: Research article Published on:

  2. Regions within solid tumours often experience oxygen deprivation, which is associated with resistance to chemotherapy and irradiation. The aim of this study was to evaluate the radiosensitising effect of gemci...

    Authors: An Wouters, Bea Pauwels, Natalie Burrows, Marc Baay, Vanessa Deschoolmeester, Trung Nghia Vu, Kris Laukens, Paul Meijnders, Dirk Van Gestel, Kaye J Williams, Danielle Van den Weyngaert, Jan B Vermorken, Patrick Pauwels, Marc Peeters and Filip Lardon
    Citation: BMC Cancer 2014 14:594
    Content type: Research article Published on:

  4. Paraneoplastic neurological syndromes (PNS) have frequently been described in patients with lung or breast cancer. However, some reports also described a correlation to carcinoid tumors, probably triggered via...

    Authors: Michael Boch, Anja Rinke, Peter Rexin, Maria Seipelt, Dörte Brödje, Marvin Schober, Thomas M Gress, Patrick Michl and Sebastian Krug
    Citation: BMC Cancer 2014 14:691
    Content type: Case report Published on:

  5. Angiosarcomas (AS) have poor prognosis and often metastasize to distant sites. The potential predictors of metastatic angiosarcomas (MAS) have not been extensively investigated. The main objective of this stud...

    Authors: Shihong Ren, Yucheng Wang, Zhan Wang, Jinxiang Shao and Zhaoming Ye
    Citation: BMC Cancer 2020 20:778
    Content type: Research article Published on:

  7. Mortality rates for cancer are decreasing in patients under 60 and increasing in those over 60 years of age. The reasons for these differences in mortality rates remain poorly understood. One explanation may b...

    Authors: Janine K Cataldo, Steven Paul, Bruce Cooper, Helen Skerman, Kimberly Alexander, Bradley Aouizerat, Virginia Blackman, John Merriman, Laura Dunn, Christine Ritchie, Patsy Yates and Christine Miaskowski
    Citation: BMC Cancer 2013 13:6
    Content type: Research article Published on:

  8. Novel biomarkers are required to discern between breast tumors that should be targeted for treatment from those that would never become clinically apparent and/or life threatening for patients. Moreover, thera...

    Authors: Catharina Hagerling, Mark Owyong, Vaishnavi Sitarama, Chih-Yang Wang, Charlene Lin, Renske J. E. van den Bijgaart, Charlotte D. Koopman, Audrey Brenot, Ankitha Nanjaraj, Fredrik Wärnberg, Karin Jirström, Ophir D. Klein, Zena Werb and Vicki Plaks
    Citation: BMC Cancer 2020 20:542
    Content type: Research article Published on:

  9. This study was designed to investigate the efficacy and safety of the epidermal growth factor receptor (EGFR) inhibitor cetuximab combined with irinotecan, folinic acid (FA) and two different doses of infusion...

    Authors: Jean-Luc Raoul, Jean-Luc Van Laethem, Marc Peeters, Catherine Brezault, Fares Husseini, Laurent Cals, Johannes Nippgen, Anja-Helena Loos and Philippe Rougier
    Citation: BMC Cancer 2009 9:112
    Content type: Research article Published on:

  10. The incidence of recurrent laryngeal nerve (RLN) injury has increased due to RLN lymph node dissection. The aim of this study was to evaluate the ability of intraoperative ultrasonography (IU) to detect RLN no...

    Authors: Jianwei Wang, Min Liu, Jingxian Shen, Haichao Ouyang, Xiuying Xie, Ting Lin, Anhua Li and Hong Yang
    Citation: BMC Cancer 2018 18:737
    Content type: Research article Published on:

  11. The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-...

    Authors: Tone Hoel Lende, Marie Austdal, Tone Frost Bathen, Anne Elin Varhaugvik, Ivar Skaland, Einar Gudlaugsson, Nina G. Egeland, Siri Lunde, Lars A. Akslen, Kristin Jonsdottir, Emiel A. M. Janssen, Håvard Søiland and Jan P. A. Baak
    Citation: BMC Cancer 2019 19:1183
    Content type: Research article Published on:

  12. Virtually all metastatic patients with metastatic melanoma who progress after initial treatment with PD-1 or CTLA-4 directed antibodies will die of their disease. Salvage options are urgently needed. It is the...

    Authors: Wolfram Samlowski and Camille Adajar
    Citation: BMC Cancer 2021 21:1187
    Content type: Research article Published on:

  13. The recommended cumulative doxorubicin dose in soft tissue sarcoma (STS) treatment was based on cardiotoxicity data from retrospective studies of breast cancer patients. However, the treatment and prognosis of...

    Authors: Zhichao Tian, Yang Yang, Yonghao Yang, Fan Zhang, Po Li, Jiaqiang Wang, Jinpo Yang, Peng Zhang, Weitao Yao and Xin Wang
    Citation: BMC Cancer 2020 20:1139
    Content type: Research article Published on:

  14. Despite our growing knowledge about the pathomechanisms of cancer cachexia, a whole clinical picture of the cachectic patient is still missing. Our objective was to evaluate the clinical characteristics in can...

    Authors: S. Schwarz, O. Prokopchuk, K. Esefeld, S. Gröschel, J. Bachmann, S. Lorenzen, H. Friess, M. Halle and M. E. Martignoni
    Citation: BMC Cancer 2017 17:130
    Content type: Research article Published on:

  15. MNAT1 (menage a trois 1, MAT1), a cyclin-dependent kinase-activating kinase (CAK) complex, highly expressed in diverse cancers and was involved in cancer molecular pathogenesis. However, its deliverance profil...

    Authors: Chensheng Qiu, Weiliang Su, Nana Shen, Xiaoying Qi, Xiaolin Wu, Kai Wang, Lin Li, Zhu Guo, Hao Tao, Guanrong Wang, Bohua Chen and Hongfei Xiang
    Citation: BMC Cancer 2020 20:1187
    Content type: Research article Published on:

  17. SLIT-ROBO families of proteins mediate axon pathfinding and their expression is not solely confined to nervous system. Aberrant expression of SLIT-ROBO genes was repeatedly shown in a wide variety of cancers, yet...

    Authors: Mehmet Ender Avci, Ozlen Konu and Tamer Yagci
    Citation: BMC Cancer 2008 8:392
    Content type: Research article Published on:

  18. Helicobacter pylori infection is recognized as the main risk factor for gastric cancer (GC), the fifth most common neoplasia worldwide. H. pylori interacts with the immune system, disrupting the cytokine network ...

    Authors: Cecilia Martínez-Campos, Kirvis Torres-Poveda, Margarita Camorlinga-Ponce, Lourdes Flores-Luna, Carmen Maldonado-Bernal, Vicente Madrid-Marina and Javier Torres
    Citation: BMC Cancer 2019 19:453
    Content type: Research article Published on:

  19. The biological effects of CD24 (FL-80) cross-linking on breast cancer cells have not yet been established. We examined the impact of CD24 cross-linking on human breast cancer cell line MCF-7.

    Authors: Jong Bin Kim, Eunyoung Ko, Wonshik Han, Jeong Eon Lee, Kyung-Min Lee, Incheol Shin, Sangmin Kim, Jong Won Lee, Jihyoung Cho, Ji-Yeon Bae, Hyeon-Gun Jee and Dong-Young Noh
    Citation: BMC Cancer 2008 8:118
    Content type: Research article Published on:

  20. Tumor necrosis (TN) correlates with adverse outcomes in numerous solid tumors. However, its prognostic value in renal cell carcinoma (RCC) remains unclear. In this study, we performed a meta-analysis to evaluate ...

    Authors: Lijin Zhang, Zhenlei Zha, Wei Qu, Hu Zhao, Jun Yuan, Yejun Feng and Bin Wu
    Citation: BMC Cancer 2018 18:870
    Content type: Research article Published on:

  21. Osteosarcoma (OS) is one of the most common primary bone malignant tumors. Osteoclasts have been shown to have a valuable role in OS. In the present study, we analyzed the differentiation states of osteoclasts...

    Authors: Haiyu Shao, Meng Ge, Jun Zhang, Tingxiao Zhao and Shuijun Zhang
    Citation: BMC Cancer 2022 22:288
    Content type: Research Published on:

  22. Ovarian cancer (OC) is the second most frequent gynecological cancer and is associated with a poor prognosis because OC progression is often asymptoma-tic and is detected at a late stage. There remains an urge...

    Authors: Bin Liu, Xiaojie Huang, Yifang Li, Weiguo Liao, Mingyi Li, Yi Liu, Rongrong He, Du Feng, Runzhi Zhu and Hiroshi Kurihara
    Citation: BMC Cancer 2019 19:645
    Content type: Research article Published on:

  24. Oral squamous cell carcinoma (OSCC) represents the most common oral malignancy. Despite recent advances in therapy, up to 50% of the cases have relapse and/or metastasis. There is therefore a strong need for t...

    Authors: Roberta Bacchiocchi, Corrado Rubini, Elisa Pierpaoli, Giulia Borghetti, Pasquale Procacci, Pier Francesco Nocini, Andrea Santarelli, Romina Rocchetti, Domenico Ciavarella, Lorenzo Lo Muzio and Francesca Fazioli
    Citation: BMC Cancer 2008 8:220
    Content type: Research article Published on:

  25. Renal cell carcinoma (RCC) is a tumor with immunogenic properties. Soluble interleukin-2 receptor (sIL-2R) has a role in T cell activation and may be important for immune regulation in various conditions, incl...

    Authors: Akinori Nukui, Akinori Masuda, Hideyuki Abe, Kyoko Arai, Ken-Ichiro Yoshida and Takao Kamai
    Citation: BMC Cancer 2017 17:372
    Content type: Research article Published on:

  26. Clear cell carcinomas are aggressive tumors with a distinct biologic behaviour. In a genome-wide screening for genes involved in chemo-resistance, NAPA was over-expressed in cisplatin-resistant cells. The NAPA...

    Authors: Ingiridur Skirnisdottir, Kathrine Bjersand, Helena Ã…kerud and Tomas Seidal
    Citation: BMC Cancer 2013 13:524
    Content type: Research article Published on:

  27. To identify the spatial patterns of regional lymph node failure of locally advanced hypopharyngeal squamous cell carcinoma (SCC) after first-line treatment with surgery and/or intensity-modulated radiotherapy ...

    Authors: Dongqing Wang, Shui Yu, Limin Zhai, Jin Xu and Baosheng Li
    Citation: BMC Cancer 2020 20:283
    Content type: Research article Published on:

  29. The purpose of this observational study was to evaluate feasibility, efficacy results and toxicity observations of capecitabine in routine first line treatment of patients with metastatic colorectal cancer, wi...

    Authors: Alexander Stein, Julia Quidde, Jan Klaus Schröder, Thomas Göhler, Barbara Tschechne, Annette-Rosel Valdix, Heinz-Gert Höffkes, Silke Schirrmacher-Memmel, Tim Wohlfarth, Axel Hinke, Andreas Engelen and Dirk Arnold
    Citation: BMC Cancer 2016 16:82
    Content type: Research article Published on:

  30. There is an unmet clinical need for better prognostic and diagnostic tools for renal cell carcinoma (RCC).

    Authors: Gabriela Gremel, Dijana Djureinovic, Marjut Niinivirta, Alexander Laird, Oscar Ljungqvist, Henrik Johannesson, Julia Bergman, Per-Henrik Edqvist, Sanjay Navani, Naila Khan, Tushar Patil, Ã…sa Sivertsson, Mathias Uhlén, David J. Harrison, Gustav J. Ullenhag, Grant D. Stewart…
    Citation: BMC Cancer 2017 17:9
    Content type: Research article Published on:

  31. Although the significance of preoperative nutritional status has been investigated, there is no report regarding the relationship of their postoperative changes on outcomes in patients who underwent radical cy...

    Authors: Makito Miyake, Yosuke Morizawa, Shunta Hori, Nagaaki Marugami, Keiji Shimada, Daisuke Gotoh, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Nobumichi Tanaka and Kiyohide Fujimoto
    Citation: BMC Cancer 2017 17:237
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2017 17:353

  32. To investigate the long-term efficacy of the minimally invasive Ivor Lewis esophagectomy (MIILE) in esophageal squamous cell carcinoma (ESCC) patients, a retrospective comparison of the quality of life (QOL) a...

    Authors: Qi Wang, Zixiang Wu, Tianwei Zhan, Shuai Fang, Sai Zhang, Gang Shen and Ming Wu
    Citation: BMC Cancer 2019 19:500
    Content type: Research article Published on:

  33. Although several single-nucleotide polymorphisms in microRNA (miRNA) genes have been associated with primary hepatocellular carcinoma, published findings regarding this relationship are inconsistent and inconc...

    Authors: Jia-Hui Qi, Jin Wang, Jinyun Chen, Fan Shen, Jing-Tao Huang, Subrata Sen, Xin Zhou and Song-Mei Liu
    Citation: BMC Cancer 2014 14:643
    Content type: Research article Published on:

  34. In the existing next generation sequencing (NGS) system, epidermal growth factor receptor (EGFR) exon 19 deletion-insertion (19delins) is still interpreted into the category of EGFR exon 19 deletion (19del). H...

    Authors: Yurong Wang, Ruipan Zheng, Peizhu Hu, Ziheng Zhang, Shujing Shen and Xingya Li
    Citation: BMC Cancer 2021 21:1215
    Content type: Research article Published on:

  35. Uterine serous carcinoma (USC) is a rare but aggressive subtype of endometrial carcinoma. Large-scale comprehensive efforts have resulted in an improved molecular understanding of its pathogenesis, and the p53...

    Authors: Katharina Bischof, Stian Knappskog, Ingunn Stefansson, Emmet Martin McCormack, Jone Trovik, Henrica Maria Johanna Werner, Kathrine Woie, Bjorn Tore Gjertsen and Line Bjorge
    Citation: BMC Cancer 2018 18:684
    Content type: Research article Published on:

  36. Lymphovascular invasion (LVI) is a crucial predictor of lymph node metastasis (LNM). However, few studies have investigated the LVI positivity rate and its clinical significance in pT1b esophageal squamous cel...

    Authors: Linxiu Liu, Hua Lin, Guihua Shen, Yong Liu, Xiumin Qin, Yanling Yuan, Bingzhi Wang and Liyan Xue
    Citation: BMC Cancer 2023 23:370
    Content type: Research Published on:

  37. Serum tartrate-resistant acid phosphatase 5b (TRACP 5b) activity is a marker of osteoclast number and is elevated in breast cancer (BC) patients with extensive bone metastasis, which might in turn reflect the ...

    Authors: Yi-Ying Wu, Anthony J Janckila, Chih-Hung Ku, Cheng-Ping Yu, Jyh-Cherng Yu, Su-Hui Lee, Hsin-Yi Liu, Lung T Yam and Tsu-Yi Chao
    Citation: BMC Cancer 2010 10:158
    Content type: Research article Published on:

  38. Head and neck mucosal melanoma (HNMM) is a rare type of malignant tumor that frequently exhibits postoperative recurrence and distant metastasis. Many clinicians administer postoperative adjuvant radiotherapy ...

    Authors: Wei Li, Yalian Yu, Hailong Wang, Aihui Yan and Xuejun Jiang
    Citation: BMC Cancer 2015 15:758
    Content type: Research article Published on:

  39. Pulmonary neuroendocrine tumors (Pulmonary NETs) include a wide spectrum of tumors, from the low-grade typical carcinoid (TC) and the intermediate-grade atypical carcinoid (AC), to the high-grade large-cell ne...

    Authors: Jose A Galván, Aurora Astudillo, Aitana Vallina, Guillermo Crespo, Maria Victoria Folgueras and Maria Victoria González
    Citation: BMC Cancer 2014 14:855
    Content type: Research article Published on:

  40. To compare the efficacy of sorafenib and sunitinib with regard to overall survival (OS) and progression free survival (PFS) in Chinese patients with metastatic renal cell carcinoma (mRCC).

    Authors: Hai-Liang Zhang, Xi-Nan Sheng, Xue-Song Li, Hong-Kai Wang, Zhi-Hong Chi, Zhi-Song He, Ding-Wei Ye and Jun Guo
    Citation: BMC Cancer 2017 17:16
    Content type: Research article Published on:

  41. Tumor immune-escape has been related to the ability of cancer cells to inhibit T cell activation and dendritic cell (DC) differentiation. We previously identified a tumor initiating population, expressing the ...

    Authors: Cristina Grange, Marta Tapparo, Stefania Tritta, Maria Chiara Deregibus, Antonino Battaglia, Paolo Gontero, Bruno Frea and Giovanni Camussi
    Citation: BMC Cancer 2015 15:1009
    Content type: Research article Published on:

  42. This study aimed to determine whether synchrotron radiation (SR)-based X-ray in-line phase-contrast imaging (IL-PCI) can be used to investigate the morphological characteristics of tumor neovascularization in ...

    Authors: Beilei Li, Yiqiu Zhang, Weizhong Wu, Guohao Du, Liang Cai, Hongcheng Shi and Shaoliang Chen
    Citation: BMC Cancer 2017 17:73
    Content type: Research article Published on:

  44. Endometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. We report a case in which a patient with a history of end...

    Authors: Ningning Li, Weixun Zhou, Lin Zhao and Jiaolin Zhou
    Citation: BMC Cancer 2018 18:905
    Content type: Case report Published on:

  45. Nurr1, a member of the orphan receptor family, plays an important role in several types of cancer. Our previous work demonstrated that increased expression of Nurr1 plays a significant role in the initiation a...

    Authors: Jian Wang, Zhi-Hong Yang, Hua Chen, Hua-Hui Li, Li-Yong Chen, Zhu Zhu, Ying Zou, Cong-Cong Ding, Jing Yang and Zhi-Wei He
    Citation: BMC Cancer 2016 16:257
    Content type: Research article Published on:

  46. Since targeting oxidative stress markers has been recently recognized as a novel therapeutic target in cancer, it is interesting to investigate whether genetic susceptibility may modify oxidative stress respon...

    Authors: Ewa Jablonska, Jolanta Gromadzinska, Beata Peplonska, Wojciech Fendler, Edyta Reszka, Magdalena B. Krol, Edyta Wieczorek, Agnieszka Bukowska, Peter Gresner, Michal Galicki, Oskar Zambrano Quispe, Zbigniew Morawiec and Wojciech Wasowicz
    Citation: BMC Cancer 2015 15:657
    Content type: Research article Published on:

  47. Renal cell carcinoma (RCC) is a seventh ranked malignancy with poor prognosis. RCC is lethal at metastatic stage as it does not respond to conventional systemic treatments, and there is an urgent need to find ...

    Authors: Sajjad Karim, Jaudah A. Al-Maghrabi, Hasan M. A. Farsi, Ahmad J. Al-Sayyad, Hans-Juergen Schulten, Abdelbaset Buhmeida, Zeenat Mirza, Alaa A. Al-boogmi, Fai T. Ashgan, Manal M. Shabaad, Hend F. NourEldin, Khalid B. M. Al-Ghamdi, Adel Abuzenadah, Adeel G. A. Chaudhary and Mohammed H. Al-Qahtani
    Citation: BMC Cancer 2016 16(Suppl 2):741
    Content type: Research article Published on:

    This article is part of a Supplement: Volume 16 Supplement 2

  48. Thymomas are typically slow-growing tumors and AB type thymomas are considered no/low risk tumors with a better prognosis. Extra-thoracic metastases are extremely rare. To the best of our knowledge, no patient...

    Authors: Yuichi Aoki, Atsushi Miki, Tomoyuki Nakano, Hideki Sasanuma, Yasunaru Sakuma, Hisanaga Horie, Yoshinori Hosoya, Noriyoshi Fukushima, Alan Kawarai Lefor and Naohiro Sata
    Citation: BMC Cancer 2018 18:1249
    Content type: Case report Published on:

  49. Recent advances in genomics, proteomics, and the increasing demands for biomarker validation studies have catalyzed changes in the landscape of cancer research, fueling the development of tissue banks for tran...

    Authors: Sambit K Mohanty, Amita T Mistry, Waqas Amin, Anil V Parwani, Andrew K Pople, Linda Schmandt, Sharon B Winters, Erin Milliken, Paula Kim, Nancy B Whelan, Ghada Farhat, Jonathan Melamed, Emanuela Taioli, Rajiv Dhir, Harvey I Pass and Michael J Becich
    Citation: BMC Cancer 2008 8:91
    Content type: Research article Published on:

  50. Malignant pleural mesothelioma (MPM) is a tumour arising from pleural cavities with poor prognosis. Multimodality treatment with pemetrexed combined with cisplatin shows unsatisfying response-rates of 40%. The...

    Authors: Sabrina Borchert, Michael Wessolly, Jan Schmeller, Elena Mairinger, Jens Kollmeier, Thomas Hager, Thomas Mairinger, Thomas Herold, Daniel C. Christoph, Robert F. H. Walter, Wilfried E. E. Eberhardt, Till Plönes, Jeremias Wohlschlaeger, Clemens Aigner, Kurt Werner Schmid and Fabian D. Mairinger
    Citation: BMC Cancer 2019 19:108
    Content type: Research article Published on:

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