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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. The cytoskeletal organizer ezrin is a member of the ezrin-radixin-moesin (ERM) family and plays important roles in not only cell motility, cell adhesion, and apoptosis, but also in various cell signaling pathw...

    Authors: Tiefeng Jin, Jingchun Jin, Xiangyu Li, Songnan Zhang, Yun Ho Choi, Yingshi Piao, Xionghu Shen and Zhenhua Lin
    Citation: BMC Cancer 2014 14:191
    Content type: Research article Published on:

  2. DTL has been found to be related with multiple cancers. However, comprehensive analyses, which identify the prediction value of DTL in diagnosis, prognosis, immune infiltration and treatment, have rarely been ...

    Authors: Yumei Tang, Ye Lei, Peng Gao, Junting Jia, Huijun Du, Qitong Wang, Zhixin Yan, Chen Zhang, Guojun Liang, Yanfeng Wang, Weijun Ma, Nianzeng Xing, Le Cheng and Laifeng Ren
    Citation: BMC Cancer 2023 23:328
    Content type: Research Published on:

  3. Cancer research has devoted most of its energy over the past decades on unraveling the control mechanisms within tumor cells that govern its behavior. From this we know that the onset of cancer is the result o...

    Authors: Marlies E Heuvers, Joachim G Aerts, Robin Cornelissen, Harry Groen, Henk C Hoogsteden and Joost P Hegmans
    Citation: BMC Cancer 2012 12:580
    Content type: Review Published on:

  4. To investigate the prognostic significance of patient characteristics and clinical laboratory test results in locally advanced non-small cell lung cancer (NSCLC), and in particular the impact of diabetes melli...

    Authors: Hisao Imai, Kyoichi Kaira, Keita Mori, Akira Ono, Hiroaki Akamatsu, Shunichi Matsumoto, Tetsuhiko Taira, Hirotsugu Kenmotsu, Hideyuki Harada, Tateaki Naito, Haruyasu Murakami, Masahiro Endo, Takashi Nakajima, Masanobu Yamada and Toshiaki Takahashi
    Citation: BMC Cancer 2015 15:989
    Content type: Research article Published on:

  5. The addition of anti-angiogenesis drugs to epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor (TKI) or chemotherapy in patients with EGFR-mutant non–small cell lung cancer (NSCLC) can improve di...

    Authors: Chieh-Lung Chen, Sing-Ting Wang, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu, Hung-Jen Chen, Te-Chun Hsia and Wen-Chien Cheng
    Citation: BMC Cancer 2022 22:571
    Content type: Research Published on:

  6. The SNCA gene is a critical gene in Parkinson’s disease (PD) pathology. Accumulating evidence indicates that SNCA is involved in tumorigenesis; however, the role of SNCA in lung adenocarcinoma (LUAD) remains uncl...

    Authors: Xiuao Zhang, Zhengcun Wu and Kaili Ma
    Citation: BMC Cancer 2022 22:406
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2022 22:485

  7. Lung cancer is the most important cause of cancer-related deaths worldwide and the overall survival of patients with non-small cell lung cancer has not improved. Transforming growth factor beta or TGF-β is a p...

    Authors: Jue Li, Cheng Shen, Xin Wang, Yutian Lai, Kun Zhou, Pengfei Li, Lunxu Liu and Guowei Che
    Citation: BMC Cancer 2019 19:691
    Content type: Research article Published on:

  8. Previous studies have shown that the cell polarity protein partitioning defective 3 (Par3) plays an essential role in the formation of tight junctions and definition of apical-basal polarity. Aberrant function...

    Authors: Hiroe Nakamura, Kazunori Nagasaka, Kei Kawana, Ayumi Taguchi, Yuriko Uehara, Mitsuyo Yoshida, Masakazu Sato, Haruka Nishida, Asaha Fujimoto, Tomoko Inoue, Katsuyuki Adachi, Takeshi Nagamatsu, Takahide Arimoto, Katsutoshi Oda, Yutaka Osuga and Tomoyuki Fujii
    Citation: BMC Cancer 2016 16:897
    Content type: Research article Published on:

  9. In human pulmonary malignancies, the SRY-box containing gene 30 (SOX30) is a known cancer-suppressing gene. Nevertheless, its molecular role and clinical effects remains unknown in bladder cancer.

    Authors: Yang Liu, Han Wang, Jianhua Zhong, Chenglong Wu, Gang Yang, Yuantang Zhong, Jinghua Zhang and Aifa Tang
    Citation: BMC Cancer 2018 18:642
    Content type: Research article Published on:

  10. Several studies have shown, that circulating tumor cells (CTC) have a negative prognostic value in colorectal cancer patients. Aim of this study was to evaluate the role of CTC in specifically rectal cancer pa...

    Authors: Sebastian Hinz, Christian Röder, Jürgen Tepel, Alexander Hendricks, Clemens Schafmayer, Thomas Becker and Holger Kalthoff
    Citation: BMC Cancer 2015 15:953
    Content type: Research article Published on:

  11. Cervical cancer (CC) is one of the most common gynaecological cancers. The gene signature is believed to be reliable for predicting cancer patient survival. However, there is no relevant study on the relations...

    Authors: Luya Cai, Chuan Hu, Shanshan Yu, Lixiao Liu, Xiaobo Yu, Jiahua Chen, Xuan Liu, Fan Lin, Cheng Zhang, Wenfeng Li and Xiaojian Yan
    Citation: BMC Cancer 2020 20:1133
    Content type: Research article Published on:

  12. Cytological fluid from a needle aspiration biopsy (NAB) is obtained directly from tumor tissue, therefore many biomarker candidates will be present in high concentrations. The aim of this study was to prospect...

    Authors: Jin Hur, Hye-Jeong Lee, Ji Eun Nam, Young Jin Kim, Yoo Jin Hong, Hee Yeong Kim, Se Kyu Kim, Joon Chang, Joo-Hang Kim, Kyung Young Chung, Hye Sun Lee and Byoung Wook Choi
    Citation: BMC Cancer 2012 12:392
    Content type: Research article Published on:

  13. Central nervous system is a common site of metastasis in NSCLC and confers worse prognosis and quality of life. The aim of this prospective study was to evaluate the prognostic significance of clinical-patholo...

    Authors: Oscar Arrieta, David Saavedra-Perez, Roberto Kuri, Alejandro Aviles-Salas, Luis Martinez, Daniel Mendoza-Posada, Patricia Castillo, Alma Astorga, Enrique Guzman and Jaime De la Garza
    Citation: BMC Cancer 2009 9:119
    Content type: Research article Published on:

  14. Lung cancer is one of the most lethal and most prevalent malignant tumors worldwide, and lung squamous cell carcinoma (LUSC) is one of the major histological subtypes. Although numerous biomarkers have been fo...

    Authors: Guichuan Huang, Jing Zhang, Ling Gong, Yi Huang and Daishun Liu
    Citation: BMC Cancer 2021 21:626
    Content type: Research article Published on:

  16. Five-year survival for lung cancer has remained at 16% over last several decades largely due to the fact that over 50% of patients are diagnosed with locally-advanced or metastatic disease. Diagnosis at an ear...

    Authors: Elena Kupert, Marshall Anderson, Yin Liu, Paul Succop, Linda Levin, Jiang Wang, Kathryn Wikenheiser-brokamp, Pingping Chen, Susan M Pinney, Trudy Macdonald, Zhongyun Dong, Sandra Starnes and Shan Lu
    Citation: BMC Cancer 2011 11:513
    Content type: Research article Published on:

  17. Tumor immune escape and angiogenesis contribute to tumor progression, and gangliosides and activation of signal transducer and activator of transcription (STAT)-3 are implicated in these processes. As both are...

    Authors: Hester van Cruijsen, Mariëlle Gallegos Ruiz, Paul van der Valk, Tanja D de Gruijl and Giuseppe Giaccone
    Citation: BMC Cancer 2009 9:180
    Content type: Research article Published on:

  18. This study aims to investigate the predictive value of the combined index smni(skeletal muscle index (SMI)-prognostic nutrition index(PNI)) for the postoperative survival of patients with advanced gastric canc...

    Authors: Yubo Han, Ju Wu, Rui Ji, Hao Tan, Simiao Tian, Jiajun Yin, Jian Xu, Xi Chen, Wenfei Liu and Hongzhang Cui
    Citation: BMC Cancer 2023 23:751
    Content type: Research Published on:

  19. Immune checkpoint inhibitors (ICIs) has shown remarkable benefit in the treatment of a range of cancer types, although it may initiate immune related adverse events (irAEs) in patients. Some studies have shown...

    Authors: Xiaoyun Zhang, Shuo Xu, Jiaqi Wang, Yalei Lv, Na Wang, Ruixue Lai, Ziyue Sha, Qun Zhao and Zhanjun Guo
    Citation: BMC Cancer 2022 22:1136
    Content type: Research Published on:

  20. Triple-negative breast cancer (TNBC) patients have relatively poor clinical outcomes. A marker predicting the prognosis of patients with TNBC could help guide treatment. Extensive evidence demonstrates that an...

    Authors: Yu-Chen Cai, Hang Yang, Ke-Feng Wang, Tan-Huan Chen, Wen-Qi Jiang and Yan-Xia Shi
    Citation: BMC Cancer 2020 20:878
    Content type: Research article Published on:

  21. Medical oncologists continue to use performance status as a proxy for quality of life (QOL) measures, as completion of QOL instruments is perceived as time consuming, may measure aspects of QOL not affected by...

    Authors: Sandro J Martins, Nelson Ho, Sueli O Cavamura, Cecilia M Harada, Crystina A Yamamoto and Teresa Y Takagaki
    Citation: BMC Cancer 2005 5:72
    Content type: Research article Published on:

  22. Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving in carcinogenesis, including lung cancer. We hypothesized that VEGF polymorphisms may affect survival outcomes among locally...

    Authors: Xiaoxiang Guan, Ming Yin, Qingyi Wei, Hui Zhao, Zhensheng Liu, Li-E Wang, Xianglin Yuan, Michael S O'Reilly, Ritsuko Komaki and Zhongxing Liao
    Citation: BMC Cancer 2010 10:431
    Content type: Research article Published on:

  23. Advanced non-small cell lung cancer (NSCLC) patients often develop thromboembolic events, including cerebral infarction (CI). However, the relationship between advanced NSCLC and CI has not been thoroughly inv...

    Authors: Motoyasu Kato, Takehito Shukuya, Keita Mori, Ryota Kanemaru, Yuichiro Honma, Yuta Nanjo, Keiko Muraki, Rina Shibayama, Ryo Koyama, Naoko Shimada, Fumiyuki Takahashi and Kazuhisa Takahashi
    Citation: BMC Cancer 2016 16:203
    Content type: Research article Published on:

  24. SOX genes play an important role in a number of developmental processes. Potential roles of SOXs have been demonstrated in various neoplastic tissues as tumor suppressors or promoters depending on tumor status...

    Authors: Wei-de Zhong, Guo-qiang Qin, Qi-shan Dai, Zhao-dong Han, Shan-ming Chen, Xiao-hui Ling, Xin Fu, Chao Cai, Jia-hong Chen, Xi-bin Chen, Zhuo-yuan Lin, Ye-han Deng, Shu-lin Wu, Hui-chan He and Chin-lee Wu
    Citation: BMC Cancer 2012 12:248
    Content type: Research article Published on:

  25. Glucose and glutamine are the main energy sources for tumor cells. Whether glycolysis and glutaminolysis play a critical role in driving the molecular subtypes of lung adenocarcinoma (LUAD) is unknown. This st...

    Authors: Jinjin Zhang, Xiaopeng Wang, Congkuan Song and Qi Li
    Citation: BMC Cancer 2023 23:152
    Content type: Research Published on:

  27. Controversy exists regarding the relationship of the outcome of patients with colorectal cancer (CRC) with the time from symptom onset to diagnosis. The aim of this study is to investigate this association, wi...

    Authors: Magdalena Esteva, Alfonso Leiva, María Ramos-Monserrat, Alejandro Espí, Luis González-Luján, Francesc Macià, Cristiane Murta-Nascimento, María A. Sánchez-Calavera, Rosa Magallón, Vanesa Balboa-Barreiro, Teresa Seoane-Pillado and Sonia Pertega-Díaz
    Citation: BMC Cancer 2022 22:910
    Content type: Research Published on:

  28. Despite the recent progress in the development of anti-cancer drugs, the treatment of metastatic tumors is usually ineffective. The systemic inflammatory response performs key roles in different stages of the ...

    Authors: O. Abu-Shawer, M. Abu-Shawer, N. Hirmas, A. Alhouri, A. Massad, B. Alsibai, H. Sultan, H. Hammo, M. Souleiman, Y. Shebli and M. Al-Hussaini
    Citation: BMC Cancer 2019 19:141
    Content type: Research article Published on:

  29. Growing evidence indicates that inflammation contributes to cancer progression, and several inflammatory markers have been reported to be associated with the clinical outcomes in patients with various types of...

    Authors: Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Tatsunari Fukuoka, Shinji Matsutani, Kenjiro Kimura, Ryosuke Amano, Kosei Hirakawa and Masaichi Ohira
    Citation: BMC Cancer 2019 19:241
    Content type: Research article Published on:

  30. There is still a debate regarding whether regimens combining irinotecan with platinum could replace regimens combining etoposide with platinum, as first-line chemotherapy for extensive-stage small cell lung ca...

    Authors: Fei Xu, Xiaoli Ren, Yuan Chen, Qianxia Li, Ruichao Li, Yu Chen and Shu Xia
    Citation: BMC Cancer 2018 18:808
    Content type: Research article Published on:

  31. Knowledge on immunosuppressive factors in the pathogenesis of endometrial cancer is scarce. The aim of this study was to assess Glycodelin (Gd) and its immunosuppressive isoform Glycodelin A (GdA) in endometri...

    Authors: Miriam Lenhard, Sabine Heublein, Christiane Kunert-Keil, Thomas Vrekoussis, Isabel Lomba, Nina Ditsch, Doris Mayr, Klaus Friese and Udo Jeschke
    Citation: BMC Cancer 2013 13:616
    Content type: Research article Published on:

  32. Chemokines are well known inflammatory factors critical for tumor development in diverse tissues, including lung cancer. Chemokine (C-C motif) Ligand 2 (CCL2) was one of such chemokines important for both prim...

    Authors: Xu Li, Fangcai Lin and Hong Zhou
    Citation: BMC Cancer 2016 16:298
    Content type: Research article Published on:

  33. PD-L1 overexpression is commonly observed in various malignancies and is strongly correlated with poor prognoses for cancer patients. Moreover, PD-L1 has been shown to play a significant role in promoting angi...

    Authors: Wenjuan Li, Jiatao Wu, Qianhao Jia, Yuqi Shi, Fan Li, Linxiang Zhang, Fan Shi, Xiaojing Wang and Shiwu Wu
    Citation: BMC Cancer 2024 24:633
    Content type: Research Published on:

  34. The tumor microenvironment (TME) in breast cancer plays a vital role in occurrence, development, and therapeutic responses. However, immune and stroma constituents in the TME are major obstacles to understandi...

    Authors: Xiao Chen, Jianzhong Zhang, Xinhan Lei, Lei Yang, Wanwan Li, Lu Zheng, Shuai Zhang, Yihan Ding, Jianing Shi, Lei Zhang, Jia Li, Tong Tang and WenJun Jia
    Citation: BMC Cancer 2023 23:129
    Content type: Research Published on:

  35. To evaluate the outcome of patients treated with stereotactic ablative body radiotherapy (SABR) with curative intent for stage I non-small cell lung cancer (NSCLC) with regard to local, regional and distant tu...

    Authors: Emilie Dubaere, Mathilde Goffaux, Marie Wanet, Benoit Bihin, Céline Gheldof, Anne-Sophie Demoulin, Antoine Bolly, Frederique Bustin, Fabrice Duplaquet, Paul-Emile Baugnee, Michel Gustin, Vincent Hers, Fabienne Maisin, Eric Marchand, Sebahat Ocak, Lionel Pirard…
    Citation: BMC Cancer 2019 19:639
    Content type: Research article Published on:

  36. Cysteine-rich 61 (Cyr61), a member of the CCN protein family, possesses diverse functionality in cellular processes such as adhesion, migration, proliferation, and survival. Cyr61 can also function as an oncog...

    Authors: Dongjun Jeong, Suhak Heo, Tae Sung Ahn, Sookyoung Lee, Soyoung Park, Hyungjoo Kim, Doosan Park, Sang Byung Bae, Sung Soo Lee, Moon Soo Lee, Chang-Jin Kim and Moo Jun Baek
    Citation: BMC Cancer 2014 14:164
    Content type: Research article Published on:

  37. CCR8-expressing regulatory T cells (Tregs) are selectively localized within tumors and have gained attention as potent suppressors of anti-tumor immunity. This study focused on CCR8+ Tregs and their interaction w...

    Authors: Yoshinori Hayashi, Azumi Ueyama, Soichiro Funaki, Koichi Jinushi, Naoko Higuchi, Hitomi Morihara, Michinari Hirata, Yoji Nagira, Takuro Saito, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani and Hisashi Wada
    Citation: BMC Cancer 2024 24:627
    Content type: Research Published on:

  39. The aim of this study was to evaluate the clinical efficacy of postoperative radiotherapy (PORT), administered using three-dimensional conformal radiotherapy (3D-CRT) and our institutional standard clinical ta...

    Authors: Wen Feng, Qin Zhang, Xiao-Long Fu, Xu-Wei Cai, Zheng-Fei Zhu, Huan-Jun Yang, Jia-Qing Xiang, Ya-Wei Zhang and Hai-Quan Chen
    Citation: BMC Cancer 2015 15:348
    Content type: Research article Published on:

  40. Hepato-pulmonary metastasis of colorectal cancer (CRC) is a rare disease with poor prognosis. This study aims to establish a highly efficient nomogram model to predict overall survival (OS) and cancer-specific...

    Authors: Shenghe Deng, Zhenxing Jiang, Yinghao Cao, Junnan Gu, Fuwei Mao, Yifan Xue, Le Qin, Ke Liu, Jiliang Wang, Ke Wu and Kailin Cai
    Citation: BMC Cancer 2022 22:643
    Content type: Research Published on:

  41. All 10 patients with pathologically confirmed lung adenocarcinoma initially presented with neurological symptoms, including ... .5 years. Eight and two cases were stage III and IV, respectively, at the ... therap...

    Authors: Weiping Hong, Tongtong Zhang, Changguo Shan, Hainan Li, Tao Lin, Da Liu, Junjie Zhen, Juan Li, Mingyao Lai, Zhaoming Zhou, Cheng Zhou, Meijuan Zhou, Minghua Wang, Linbo Cai and Lei Wen
    Citation: BMC Cancer 2023 23:1096
    Content type: Research Published on:

  42. Patients with lung cancer (LC) have a poor quality of life (QoL) and easily suffer from psychological diseases. Previous studies focused less on the relationship between genetic factors and QoL, depression, an...

    Authors: Yunxiang Tang, Ruike Zhang, Yinan Li, Shuyu Xu, Hao Wang, Jingzhou Xu, Lei Xiao, Yajing Wang, Jing Du, Yujia Huang and Tong Su
    Citation: BMC Cancer 2021 21:842
    Content type: Research Published on:

  43. Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrate...

    Authors: Anna Larsson, Marie Fridberg, Alexander Gaber, Björn Nodin, Per Levéen, Göran Jönsson, Mathias Uhlén, Helgi Birgisson and Karin Jirström
    Citation: BMC Cancer 2012 12:282
    Content type: Research article Published on:

  44. Emerging inflammatory response biomarkers are developed to predict the survival of patients with cancer, the aim of our study is to establish an inflammation-related nomogram based on the classical predictive ...

    Authors: Ying Wang, Xiao Qu, Ngar-Woon Kam, Kai Wang, Hongchang Shen, Qi Liu and Jiajun Du
    Citation: BMC Cancer 2018 18:692
    Content type: Research article Published on:

  45. Accumulating evidence has revealed that long non-coding RNAs (lncRNAs) play vital roles in the progression of non-small cell lung cancer (NSCLC). But the relationship between lncRNAs and survival outcome of NS...

    Authors: Yong Yu and Kaiming Ren
    Citation: BMC Cancer 2021 21:457
    Content type: Research article Published on:

  46. Research in treatment of non-small cell lung cancer (NSCLC) has shown promising results with stereotactic ablative radiotherapy (SABR) of oligometastatic disease, wherein distant disease may be limited to one ...

    Authors: Inderdeep Dhaliwal, Shayan Kassirian, Michael A. Mitchell, Mehdi Qiabi, Andrew Warner, Alexander V. Louie, Harvey H. Wong, Christine M. McDonald, Jason Rajchgot and David A. Palma
    Citation: BMC Cancer 2022 22:468
    Content type: Study protocol Published on:

  47. There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...

    Authors: Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun, Yang-Chun Meng, Jian-Xia Xu, Ting Jiang, Zhi-Xuan Zhang, Jin-Peng Sun and Wei Wang
    Citation: BMC Cancer 2017 17:267
    Content type: Research article Published on:

  48. Studies have shown that the Sec61 gamma subunit (SEC61G) is overexpressed in several tumors and could serve as a potential prognostic marker. However, the correlation between SEC61G and lung adenocarcinoma (LU...

    Authors: Qunhao Zheng, Zhiping Wang, Mengyan Zhang, Yilin Yu, Rui Chen, Tianzhu Lu, Lingyun Liu, Jiayu Ma, Tianxiu Liu, Hongying Zheng, Hui Li and Jiancheng Li
    Citation: BMC Cancer 2021 21:1216
    Content type: Research Published on:

  49. Fringe is a glycosyltransferase involved in tumor occurrence and metastasis. However, a comprehensive analysis of the Fringe family members lunatic fringe (LFNG), manic fringe (MFNG), radical fringe (RFNG) in ...

    Authors: Xun Gong, Chenglong Zheng, Haiying Jia, Yangruiyu Liu, Rui Yang, Zizhou Chen, Yihang Pan, Xiaowu Li and Yuchen Liu
    Citation: BMC Cancer 2023 23:1065
    Content type: Research Published on:

  50. Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties.

    Authors: Sören A. Weidemann, Charlotte Sauer, Andreas M. Luebke, Christina Möller-Koop, Stefan Steurer, Claudia Hube-Magg, Franziska Büscheck, Doris Höflmayer, Maria Christina Tsourlakis, Till S. Clauditz, Ronald Simon, Guido Sauter, Cosima Göbel, Patrick Lebok, David Dum, Christoph Fraune…
    Citation: BMC Cancer 2019 19:944
    Content type: Research article Published on:

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