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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 54 of 79

  1. The incidence of Cholangiocellular Carcinoma (CCA) is increasing in the western world. The tumour has a high proportion of desmoplastic stroma and is correlated with a worse prognosis when cancer associated my...

    Authors: Nils Heits, Tillmann Heinze, Alexander Bernsmeier, Jannik Kerber, Charlotte Hauser, Thomas Becker, Holger Kalthoff, Jan-Hendrik Egberts and Felix Braun
    Citation: BMC Cancer 2016 16:322
    Content type: Research article Published on:

  2. The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with current...

    Authors: Qing-Bai She, Sofia K. Gruvberger-Saal, Matthew Maurer, Yilun Chen, Mervi Jumppanen, Tao Su, Meaghan Dendy, Ying-Ka Ingar Lau, Lorenzo Memeo, Hugo M. Horlings, Marc J. van de Vijver, Jorma Isola, Hanina Hibshoosh, Neal Rosen, Ramon Parsons and Lao H. Saal
    Citation: BMC Cancer 2016 16:587
    Content type: Research article Published on:

  3. CD26 is an ectoenzyme with dipeptidyl peptidase 4 (DPP4) activity expressed on a variety of cell types. Considering that serum CD26 levels have been previously associated with different cancers, we examined th...

    Authors: Virginia Boccardi, Luigi Marano, Rosaria Rita Amalia Rossetti, Maria Rosaria Rizzo, Natale di Martino and Giuseppe Paolisso
    Citation: BMC Cancer 2015 15:703
    Content type: Research article Published on:

  4. Small hepatocellular carcinoma (sHCC) is a special subtype of HCC with the maximum tumor diameter ≤ 3 cm and excellent long-term outcomes. Surgical resection or radiofrequency ablation provides the greatest ch...

    Authors: Yi-hong Ling, Jie-wei Chen, Shi-hong Wen, Chao-yun Huang, Peng Li, Liang-he Lu, Jie Mei, Shao-hua Li, Wei Wei, Mu-yan Cai and Rong-ping Guo
    Citation: BMC Cancer 2020 20:607
    Content type: Research article Published on:

  6. Brain metastases from gastric cancer are difficult to treat and their prognosis is poor. Despite various possible treatments, the survival rate of such patients is still unsatisfactory; therefore, new treatmen...

    Authors: Min-joo Ahn, Kanghan Lee, Kyung Hwa Lee, Jin Woong Kim, In-Young Kim and Woo Kyun Bae
    Citation: BMC Cancer 2018 18:173
    Content type: Case report Published on:

  7. In this study, we examined the differential associations of various proinflammatory and anti-inflammatory cytokines with depression severity from the development of breast cancer to subsequent chemotherapy tre...

    Authors: Bor-Show Tzang, Vincent Chin-Hung Chen, Ching-Chuan Hsieh, Wen-Ke Wang, Yi-Ping Weng, Hsing-Ying Ho, Ya-Ting Hsu, Han-Pin Hsaio, Jun-Cheng Weng and Yi-Lung Chen
    Citation: BMC Cancer 2020 20:686
    Content type: Research article Published on:

  8. Primary bone cancers are among the deadliest cancer types in adolescents, with osteosarcomas being the most prevalent form. Osteosarcomas are commonly treated with multi-drug neoadjuvant chemotherapy and thera...

    Authors: Bernhard Robl, Chantal Pauli, Sander Martijn Botter, Beata Bode-Lesniewska and Bruno Fuchs
    Citation: BMC Cancer 2015 15:379
    Content type: Research article Published on:

  9. Signaling through VEGF/VEGFR induces cancer angiogenesis and affects immune cells. An increasing number of studies have recently focused on combining anti-VEGF/VEGFR agents and immune checkpoint inhibitors (IC...

    Authors: Liting Xue, Xingyuan Gao, Haoyu Zhang, Jianxing Tang, Qian Wang, Feng Li, Xinxin Li, Xiaohong Yu, Zhihong Lu, Yue Huang, Renhong Tang and Wenqing Yang
    Citation: BMC Cancer 2021 21:1134
    Content type: Research Published on:

  10. Pancreatic ductal adenocarcinoma (PDAC) is a ‘difficult-to-treat’ entity. To forecast its prognosis, we introduced a new biomarker, SARIFA (stroma areactive invasion front areas), which are areas at the tumour...

    Authors: Przemyslaw Grochowski, Bianca Grosser, Florian Sommer, Andreas Probst, Johanna Waidhauser, Gerhard Schenkirsch, Nic G. Reitsam and Bruno Märkl
    Citation: BMC Cancer 2024 24:768
    Content type: Research Published on:

  11. Transcripts with alternative 5′-untranslated regions (UTRs) result from the activity of alternative promoters and they can determine gene expression by influencing its stability and translational efficiency, t...

    Authors: Tamara Babic, Sandra Dragicevic, Marko Miladinov, Zoran Krivokapic and Aleksandra Nikolic
    Citation: BMC Cancer 2022 22:72
    Content type: Research Published on:

  12. Though sepsis is common in patients with cancer, there are limited studies that evaluated sepsis and septic shock in this patient population. The objective of this study was to evaluate the outcomes and to ide...

    Authors: Wedad B. Awad, Lama Nazer, Salam Elfarr, Maha Abdullah and Feras Hawari
    Citation: BMC Cancer 2021 21:709
    Content type: Research Published on:

  13. As a consequence of effective treatment procedures, the number of long-term survivors of colorectal cancer is ever increasing. Adopting the method of a previous study on breast cancer patients, the goal of the...

    Authors: Vinzenz Völkel, Brunhilde Steinger, Michael Koller, Monika Klinkhammer-Schalke and Patricia Lindberg-Scharf
    Citation: BMC Cancer 2023 23:149
    Content type: Research Published on:

  14. The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that informs clinical decisions regarding recurrence and overall survival in most epithelial cancers. Radiotherapy for head and nec...

    Authors: Yumiko Kawashita, Masayasu Kitamura, Sakiko Soutome, Takashi Ukai, Masahiro Umeda and Thoshiyuki Saito
    Citation: BMC Cancer 2021 21:1064
    Content type: Research Published on:

  15. The functional and clinical significance of 14-3-3 proteins in human cancers remain largely undetermined. Earlier, we have reported differential expression of 14-3-3ζ mRNA in oral squamous cell carcinoma (OSCC...

    Authors: Ajay Matta, Sudhir Bahadur, Ritu Duggal, Siddhartha D Gupta and Ranju Ralhan
    Citation: BMC Cancer 2007 7:169
    Content type: Research article Published on:

  16. Recognizing resistance or susceptibility to the current standard cisplatin and paclitaxel treatment could improve therapeutic outcomes of metastatic or recurrent cervical cancer.

    Authors: Sofia Karageorgopoulou, Ioannis D. Kostakis, Maria Gazouli, Sonia Markaki, Marios Papadimitriou, Evangelos Bournakis, Meletios-Athanassios Dimopoulos and Christos A Papadimitriou
    Citation: BMC Cancer 2017 17:451
    Content type: Research article Published on:

  17. The incidence of oral and pharyngeal (including oral cavity, oropharynx and hypopharynx) carcinoma increases rapidly in Asia and South Pacific because of betel quid chewing. Thus far, large-scale epidemiologic...

    Authors: Kuan-Der Lee, Chang-Hsien Lu, Ping-Tsung Chen, Chunghuang Hubert Chan, Jen-Tsun Lin, Cih-En Huang, Chih-Cheng Chen and Min-Chi Chen
    Citation: BMC Cancer 2009 9:373
    Content type: Research article Published on:

  18. Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop bett...

    Authors: Chiara Giacomelli, Janine Jung, Astrid Wachter, Susanne Ibing, Rainer Will, Stefan Uhlmann, Heiko Mannsperger, Özgür Sahin, Yosef Yarden, Tim Beißbarth, Ulrike Korf, Cindy Körner and Stefan Wiemann
    Citation: BMC Cancer 2021 21:1296
    Content type: Research article Published on:

  19. Breast cancer is highly heterogeneous, suggesting that small but relevant subsets have been under-recognized. Rare and mainly triple-negative breast cancers (TNBCs) were recently found to exhibit tuft cell-lik...

    Authors: Yosuke Yamada, Ronald Simon, Kosuke Iwane, Yuki Nakanishi, Yasuhide Takeuchi, Akihiko Yoshizawa, Masahiro Takada, Masakazu Toi, Hironori Haga, Alexander Marx and Guido Sauter
    Citation: BMC Cancer 2023 23:438
    Content type: Research Published on:

  20. Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds target...

    Authors: Maria Rosaria Ambrosio, Elisa Magli, Giuseppe Caliendo, Rosa Sparaco, Paola Massarelli, Vittoria D’Esposito, Teresa Migliaccio, Giusy Mosca, Ferdinando Fiorino and Pietro Formisano
    Citation: BMC Cancer 2022 22:171
    Content type: Research Published on:

  21. Liver metastasis is a poor prognostic factor for treatment of advanced cutaneous melanoma with either immunotherapy or targeted therapies. In this study we focused on NRAS mutated melanoma, a cohort with high unm...

    Authors: Bianca Dietsch, Céline Weller, Carsten Sticht, Carolina de la Torre, Martin Kramer, Sergij Goerdt, Cyrill Géraud and Sebastian A. Wohlfeil
    Citation: BMC Cancer 2023 23:436
    Content type: Research Published on:

  22. Aberrant expression and activation of the IGF-IR have been reported in a variety of human cancers and have been associated with resistance to HER targeted therapy. In this study, we investigated the effect of ...

    Authors: Nikolaos Ioannou, Alan M Seddon, Angus Dalgleish, David Mackintosh and Helmout Modjtahedi
    Citation: BMC Cancer 2013 13:41
    Content type: Research article Published on:

  24. Dermatomyositis is an autoimmune myopathy characterized by proximal muscle weakness, muscle inflammation, and typical skin findings. It is a rare disease with an incidence of ~1/100 000. About 15–30 % of adult...

    Authors: Ondřej Kubeček, Tomáš Soukup, Adam Paulík and Jindřich Kopecký
    Citation: BMC Cancer 2016 16:684
    Content type: Case report Published on:

  25. Recent evidence suggests an emerging role for S100 protein in breast cancer and tumor progression. These ubiquitous proteins are involved in numerous normal and pathological cell functions including inflammato...

    Authors: Jodie M Fleming, Erika Ginsburg, Shannon D Oliver, Paul Goldsmith and Barbara K Vonderhaar
    Citation: BMC Cancer 2012 12:266
    Content type: Research article Published on:

  26. The present study compared the effectiveness and toxicity of two treatment modalities, namely radiotherapy combined with nimotuzumab (N) and chemoradiotherapy (CRT) in patients with locally recurrent nasophary...

    Authors: Jing-Feng Zong, Qian-Dong Liang, Qiong-Jiao Lu, Yu-Hong Liu, Han-Chuan Xu, Bi-Juan Chen, Qiao-Juan Guo, Yun Xu, Cai-Rong Hu, Jian-Ji Pan and Shao-Jun Lin
    Citation: BMC Cancer 2021 21:1274
    Content type: Research Published on:

  27. The occurrence of skeletal muscle metastases is a very rare event. Only two cases of late skeletal muscle recurrence from cervical cancer have been documented until now.

    Authors: Gabriella Ferrandina, Vanda Salutari, Antonia Testa, Gian Franco Zannoni, Marco Petrillo and Giovanni Scambia
    Citation: BMC Cancer 2006 6:169
    Content type: Case report Published on:

  30. Radiomics is an emerging field in oncological research. In this study, we aimed at developing a radiomics score (rad-score) to estimate postoperative recurrence and survival in patients with solitary hepatocel...

    Authors: Bo-Hao Zheng, Long-Zi Liu, Zhi-Zhi Zhang, Jie-Yi Shi, Liang-Qing Dong, Ling-Yu Tian, Zhen-bin Ding, Yuan Ji, Sheng-Xiang Rao, Jian Zhou, Jia Fan, Xiao-Ying Wang and Qiang Gao
    Citation: BMC Cancer 2018 18:1148
    Content type: Research article Published on:

  33. Galectin-1 (gal-1) belongs to the family of β-galactoside-binding proteins which primarily recognizes the Galβ1-4GlcNAc sequences of oligosaccharides associated with several cell surface glycoconjugates. The l...

    Authors: Pamina Geiger, Barbara Mayer, Irmi Wiest, Sandra Schulze, Udo Jeschke and Tobias Weissenbacher
    Citation: BMC Cancer 2016 16:870
    Content type: Research article Published on:

  34. The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic changes that can eventually affect epithelial homeostasis, predisposing th...

    Authors: Camile B. Lopes, Leandro L. Magalhães, Carolina R. Teófilo, Ana Paula N. N. Alves, Raquel C. Montenegro, Massimo Negrini and Ândrea Ribeiro-dos-Santos
    Citation: BMC Cancer 2018 18:721
    Content type: Research article Published on:

  35. The microbiome has been shown to affect the response to Immune Checkpoint Inhibitors (ICIs) in a small number of cancers and in preclinical models. Here, we sought to broadly survey cancers to identify those i...

    Authors: Daniel Spakowicz, Rebecca Hoyd, Mitchell Muniak, Marium Husain, James S. Bassett, Lei Wang, Gabriel Tinoco, Sandip H. Patel, Jarred Burkart, Abdul Miah, Mingjia Li, Andrew Johns, Madison Grogan, David P. Carbone, Claire F. Verschraegen, Kari L. Kendra…
    Citation: BMC Cancer 2020 20:383
    Content type: Research article Published on:

  36. There are various recommendations for third-line treatment in mCRC, however, there is no consensus on who is more suitable for particular strategy. Chemotherapy re-use in third-line setting is a common option ...

    Authors: Jingjing Duan, Lila Zhu, Yinghui Shi, Weixue Wang, Tongtong Wang, Tao Ning, Le Zhang, Ming Bai, Hongli Li, Rui Liu, Shaohua Ge, Xia Wang, Yuchong Yang, Zhi Ji, Feixue Wang, Yansha Sun…
    Citation: BMC Cancer 2024 24:302
    Content type: Research Published on:

  37. Ewing’s sarcoma (ES) is the second most frequent primitive malignant bone tumor in adolescents with a very poor prognosis for high risk patients, mainly when lung metastases are detected (overall survival <15%...

    Authors: Guillaume Odri, Pui-Pui Kim, François Lamoureux, Céline Charrier, Séverine Battaglia, Jérôme Amiaud, Dominique Heymann, François Gouin and Françoise Redini
    Citation: BMC Cancer 2014 14:169
    Content type: Research article Published on:

  38. The advent of tyrosine kinase inhibitors (TKIs) has changed the treatment of RAI refractory, unresectable recurrent differentiated thyroid cancer (DTC), which was formerly treated with multidisciplinary remedies.

    Authors: Masayuki Tori and Toshirou Shimo
    Citation: BMC Cancer 2018 18:698
    Content type: Case report Published on:

  39. Colorectal cancer remains a major cause of cancer mortality in the Western world. A limited number of studies has been conducted in respect of Her-3 and Her-4 expression and their correlation with clinical par...

    Authors: Panteleimon Kountourakis, Kitty Pavlakis, Amanda Psyrri, Dimitra Rontogianni, Nikolaos Xiros, Efstratios Patsouris, Dimitrios Pectasides and Theofanis Economopoulos
    Citation: BMC Cancer 2006 6:46
    Content type: Research article Published on:

  40. We previously found that the low frequency magnetic fields (LF-MF) inhibited gastric and lung cancer cell growth. We suppose that exposure to LF-MF may modulate immune function so as to inhibit tumor. We here ...

    Authors: Yunzhong Nie, Leilei Du, Yongbin Mou, Zhenjun Xu, Leihua Weng, Youwei Du, Yanan Zhu, Yayi Hou and Tingting Wang
    Citation: BMC Cancer 2013 13:582
    Content type: Research article Published on:

  41. As cell-free circulating DNA exists predominantly as mono- and oligonucleosomes, the focus of the current study was to examine the interplay of circulating nucleosomes, DNA, proteases and caspases in blood of ...

    Authors: Carina Roth, Klaus Pantel, Volkmar Müller, Brigitte Rack, Sabine Kasimir-Bauer, Wolfgang Janni and Heidi Schwarzenbach
    Citation: BMC Cancer 2011 11:4
    Content type: Research article Published on:

  42. Pathologic complete response (pCR) after neoadjuvant chemotherapy for breast cancer is associated with improved prognosis in aggressive tumor subtypes, including ERBB2- positive tumors. Recent adoption of pCR ...

    Authors: Benjamin C. Calhoun, Bryce Portier, Zhen Wang, Eugen C. Minca, G. Thomas Budd, Christopher Lanigan, Raymond R. Tubbs and Larry E. Morrison
    Citation: BMC Cancer 2016 16:695
    Content type: Research article Published on:

  43. BRK is, a non-receptor tyrosine kinase, overexpressed in approximately 85% of human invasive ductal breast tumors. It is not clear whether BRK expression correlates with breast cancer subtypes, or the expressi...

    Authors: Sayem Miah, Edward Bagu, Raghuveera Goel, Yetunde Ogunbolude, Chenlu Dai, Alison Ward, Frederick S. Vizeacoumar, Gerald Davies, Franco J. Vizeacoumar, Deborah Anderson and Kiven Erique Lukong
    Citation: BMC Cancer 2019 19:78
    Content type: Research article Published on:

  44. Our recent studies suggested that the chromodomain helicase DNA binding protein 1-like (CHD1L) gene plays an oncogenic role in human hepatocellular carcinoma. However, the status of CHD1L protein expression in ov...

    Authors: Wei-Peng He, Juan Zhou, Mu-Yan Cai, Xiang-Shen Xiao, Yi-Ji Liao, Hsiang-Fu Kung, Xin-Yuan Guan, Dan Xie and Guo-Fen Yang
    Citation: BMC Cancer 2012 12:437
    Content type: Research article Published on:

  45. Inhibitors of mutant BRAF are emerging as standard of care in patients with metastatic melanoma who carry relevant oncogenic mutations. However, BRAF inhibitors are found to induce cutaneous squamous cell carc...

    Authors: Haojie Li, Lars Pedersen, Mette Nørgaard, Sinna P. Ulrichsen, Sandra K. Thygesen and Jeanenne J. Nelson
    Citation: BMC Cancer 2016 16:295
    Content type: Research article Published on:

  46. Treatment decisions in prostate cancer (PCa) rely on disease stratification between localised and metastatic stages, but current imaging staging technologies are not sensitive to micro-metastatic disease. Circ...

    Authors: Tarek Al-Hammouri, Ricardo Almeida-Magana, Rachel Lawrence, Tom Duffy, Laura White, Edwina Burke, Sakunthala Kudahetti, Justin Collins, Prabhakar Rajan, Daniel Berney, Rhian Gabe, Greg Shaw and Yong-Jie Lu
    Citation: BMC Cancer 2023 23:581
    Content type: Study Protocol Published on:

  47. The mechanisms of chemoresistance in ovarian cancer patients remain largely to be elucidated. Paclitaxel/cisplatin combination is the standard chemotherapeutic treatment for this disease, although some patient...

    Authors: Bárbara Mesquita, Isabel Veiga, Deolinda Pereira, Ana Tavares, Isabel M Pinto, Carla Pinto, Manuel R Teixeira and Sérgio Castedo
    Citation: BMC Cancer 2005 5:101
    Content type: Research article Published on:

  48. The primary aim was to test the hypothesis that deriving pre-treatment 3D magnetic resonance tumour volume (mrTV) quantification improves performance characteristics for the prediction of loco-regional failure...

    Authors: Hema Sekhar, Rohit Kochhar, Bernadette Carrington, Thomas Kaye, Damian Tolan, Mark P. Saunders, Matthew Sperrin, David Sebag-Montefiore, Marcel van Herk and Andrew G. Renehan
    Citation: BMC Cancer 2020 20:1165
    Content type: Research article Published on:

  49. The COVID-19 pandemic has caused a global health crisis. Numerous cancer patients from non-Western countries, including the United Arab Emirates (UAE), seek cancer care outside their home countries and many ar...

    Authors: Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Shabeeha K. Rana, Neil Nijhawan, Ahmed S. Abdulsamad, Sadir Alrawi, Mohamed Abuhaleeqa, Taleb M. Almansoori, Thamir Alkasab, Essa M. Aleassa and Martine C. McManus
    Citation: BMC Cancer 2020 20:641
    Content type: Review Published on:

  50. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers based on five-year survival rates. Genes contributing to chemoresistance represent novel therapeutic targets that can improve treatment r...

    Authors: Emily R. Gordon, Carter A. Wright, Mikayla James and Sara J. Cooper
    Citation: BMC Cancer 2023 23:524
    Content type: Research Published on:

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